[{"data":1,"prerenderedAt":173},["ShallowReactive",2],{"drug-mmr-vaccine":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":22,"regimens":35,"contraindications":60,"warnings":77,"renal":78,"monitoring":79,"interactions":80,"review":81,"examples":84,"atc":89,"iran":91,"links":119,"populations":134,"usApproval":168},"mmr-vaccine",1,{"fa":7,"en":8},"واکسن سرخک، اوریون و سرخجه (MMR)","MMR vaccine (measles, mumps, rubella)","anti-infectives",{"fa":11,"en":12},"واکسن زنده ضعیف‌شده","Live attenuated vaccine",[14],{"name":15,"market":16},"M-M-R II","US",[18,19,20,21],"mmr","ام ام آر","واکسن سرخک","priorix",[23],{"id":24,"form":25,"route":26,"label":27,"concentration":28,"markets":30,"refs":31},"vial-05","injection","im","0.5 mL dose after reconstitution",{"amount":5,"unit":29,"perVolumeMl":5},"mL",[16],[32],{"source":33,"section":34},"fda-mmr","3",[36],{"id":37,"disease":38,"label":39,"population":42,"type":46,"unit":29,"dose":47,"refs":49,"durationDays":52,"notes":53},"std","immunization",{"fa":40,"en":41},"دو دوز ۰٫۵ mL — ۱۲ تا ۱۵ ماهگی و ۴ تا ۶ سالگی","Two 0.5 mL doses — at 12–15 months and 4–6 years",{"minAge":43},{"value":44,"unit":45},12,"month","fixed",{"perDose":48,"dosesPerDay":5},0.5,[50],{"source":33,"section":51},"2.1",{"min":5,"max":5},[54],{"text":55,"refs":58},{"fa":56,"en":57},"دوز دوم پیش از ۴ سالگی هم مجاز است اگر دست‌کم ۱ ماه فاصله باشد. پیشگیری پس از تماس با سرخک: یک دوز ظرف ۷۲ ساعت. عضلانی یا زیرجلدی.","The second dose may be given before 4 y if at least 1 month apart. Measles post-exposure: one dose within 72 h. IM or SC.",[59],{"source":33,"section":51},[61,70],{"id":62,"severity":63,"text":64,"refs":67},"live","block",{"fa":65,"en":66},"بارداری، نقص ایمنی، بیماری تب‌دار متوسط تا شدید، سل فعال درمان‌نشده (واکسن زنده).","Pregnancy, immunosuppression, moderate or severe febrile illness, active untreated tuberculosis (live vaccine).",[68],{"source":33,"section":69},"4",{"id":71,"severity":63,"text":72,"refs":75},"allergy",{"fa":73,"en":74},"واکنش آلرژیک شدید به اجزای واکسن (از جمله ژلاتین و نئومایسین) یا دوز قبلی.","Severe allergic reaction to a vaccine component (including gelatin and neomycin) or a previous dose.",[76],{"source":33,"section":69},[],[],[],[],{"status":82,"reviewer":83,"date":83},"unverified",null,[85],{"regimen":37,"formulation":24,"input":86,"expect":88},{"ageYears":5,"weightKg":87},10,{"perDose":48,"mlPerDose":48},[90],"J07BD52",{"status":92,"forms":93,"refs":114},"registered",[94,98,102,106,110],{"code":95,"en":96,"fa":97},"01578","VACCINE-MEASLES+MUMPS+RUBELLA VIRUS 10DOSE VIAL","ویال واکسن–سرخک + اوریون + سرخجه ویروس ۱۰ دوز",{"code":99,"en":100,"fa":101},"07629","VACCINE-MEASLES+MUMPS+RUBELLA VIRUS 1DOSE VIAL","ویال واکسن–سرخک + اوریون + سرخجه ویروس ۱ دوز",{"code":103,"en":104,"fa":105},"09575","VACCINE-MEASLES+MUMPS+RUBELLA VIRUS 2DOSE VIAL","ویال واکسن–سرخک + اوریون + سرخجه ویروس ۲ دوز",{"code":107,"en":108,"fa":109},"01990","VACCINE-MEASLES+RUBELLA (10 dose) VIAL","ویال واکسن–سرخک + سرخجه (۱۰ دوز)",{"code":111,"en":112,"fa":113},"50415","MEASLES \u002F MUMPS \u002F RUBELLA VACCINE INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION PARENTERAL 5 {dose} 2.5 mL","محلول تزریقی واکسن سرخک \u002F اوریون \u002F سرخجه ۵ { دوز } ۲٫۵ میلی‌لیتر",[115],{"source":116,"section":117,"url":118},"darooyab-generic","G-3486\u002FMeasles,-Mumps,-and-Rubella-Vaccines","https:\u002F\u002Fwww.darooyab.ir\u002FG-3486\u002FMeasles,-Mumps,-and-Rubella-Vaccines",[120,124,128,131],{"kind":121,"url":122,"label":123},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=101069","BLA101069",{"kind":125,"url":126,"label":127},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=0a9e384f-e717-436b-b9a0-15e53cef0862","FDA M-M-R II",{"kind":129,"url":130,"label":90},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=J07BD52",{"kind":132,"url":118,"label":133},"darooyab","Measles,-Mumps,-and-Rubella-Vaccines",{"pregnancy":135,"lactation":143,"pediatric":152,"geriatric":160},{"level":136,"text":137,"quote":140,"refs":141},"contraindicated",{"fa":138,"en":139},"برچسب: در بارداری منع مصرف دارد.","Label: contraindicated in pregnancy.","( 4.4 ) Pregnancy.",[142],{"source":33,"section":69},{"level":144,"text":145,"quote":148,"refs":149},"caution",{"fa":146,"en":147},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Studies have shown that lactating postpartum women vaccinated with live attenuated rubella vaccine may secrete the virus in breast milk and transmit it to breast-fed infants. { 17 , 18 } In the breast-fed infants with serological evidence of rubella virus vaccine strain antibodies, none exhibited severe disease; …",[150],{"source":33,"section":151},"8.2",{"level":144,"text":153,"quote":156,"refs":157},{"fa":154,"en":155},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","Safety and effectiveness of measles vaccine in infants below the age of 6 months have not been established [see Clinical Studies (14) ] .",[158],{"source":33,"section":159},"8.4",{"level":144,"text":161,"quote":164,"refs":165},{"fa":162,"en":163},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Clinical studies of M-M-R II did not include sufficient numbers of seronegative subjects aged 65 and over to determine whether they respond differently from younger subjects.",[166],{"source":33,"section":167},"8.5",{"kind":169,"refs":170,"id":123},"BLA",[171],{"source":33,"section":172},"SPL approval \u002F marketing category",1792108431190]