[{"data":1,"prerenderedAt":157},["ShallowReactive",2],{"drug-menotropins":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":23,"regimens":38,"contraindications":62,"warnings":72,"renal":80,"monitoring":81,"interactions":82,"review":83,"examples":86,"atc":92,"iran":94,"usApproval":110,"links":116,"populations":130},"menotropins",1,{"fa":7,"en":8},"منوتروپین (hMG)","Menotropins (hMG)","genitourinary-sex-hormones",{"fa":11,"en":12},"گنادوتروپین (FSH + LH)","Gonadotropin (FSH + LH)",[14],{"name":15,"market":16},"Menopur","US",[18,19,20,21,22],"menopur","hmg","منوپور","منوتروپین","اچ ام جی",[24],{"id":25,"form":26,"route":27,"label":28,"concentration":29,"markets":33,"refs":34},"vial-75","powder-for-injection","sc","75 IU FSH + 75 IU LH per vial",{"amount":30,"unit":31,"perUnit":32},75,"unit","vial",[16],[35],{"source":36,"section":37},"fda-menopur","3",[39],{"id":40,"disease":41,"label":42,"population":45,"type":49,"unit":31,"dose":50,"refs":52,"notes":55},"art","female-infertility",{"fa":43,"en":44},"تحریک تخمک‌گذاری در IVF (پس از آگونیست GnRH) — شروع ۲۲۵ واحد زیرجلدی روزانه از روز ۲ یا ۳ سیکل","Ovarian stimulation for IVF (after GnRH agonist) — start 225 IU SC daily from cycle day 2 or 3",{"minAge":46},{"value":47,"unit":48},18,"year","fixed",{"perDose":51,"dosesPerDay":5},225,[53],{"source":36,"section":54},"2.2",[56],{"text":57,"refs":60},{"fa":58,"en":59},"پس از ۵ روز بر اساس سونوگرافی و استرادیول تنظیم؛ هر بار حداکثر ۱۵۰ واحد و نه زودتر از هر ۲ روز؛ حداکثر ۴۵۰ واحد\u002Fروز و ۲۰ روز. سپس hCG.","Adjust after 5 days by ultrasound and oestradiol; at most 150 IU per change and not more often than every 2 days; max 450 IU\u002Fday and 20 days. Then hCG.",[61],{"source":36,"section":54},[63],{"id":64,"severity":65,"text":66,"refs":69},"ci","block",{"fa":67,"en":68},"حساسیت به منوتروپین؛ FSH بالا (نارسایی اولیه تخمدان)؛ بارداری؛ اختلال غدد درون‌ریز کنترل‌نشده غیرگنادی (تیروئید، آدرنال، هیپوفیز)؛ تومورهای وابسته به هورمون جنسی؛ کیست تخمدان غیر از PCOS؛ خونریزی رحمی نامشخص.","Hypersensitivity to menotropins; high FSH (primary ovarian failure); pregnancy; uncontrolled non-gonadal endocrinopathies (thyroid, adrenal, pituitary); sex-hormone-dependent tumours; ovarian cysts not due to PCOS; abnormal uterine bleeding of undetermined origin.",[70],{"source":36,"section":71},"4",[73],{"text":74,"refs":77},{"fa":75,"en":76},"بزرگی غیرطبیعی تخمدان؛ OHSS؛ عوارض ریوی و عروقی؛ پیچ‌خوردگی تخمدان؛ بارداری چندقلو؛ حاملگی خارج رحمی.","Abnormal ovarian enlargement; OHSS; pulmonary and vascular complications; ovarian torsion; multiple gestation; ectopic pregnancy.",[78],{"source":36,"section":79},"5",[],[],[],{"status":84,"reviewer":85,"date":85},"unverified",null,[87],{"regimen":40,"formulation":25,"input":88,"expect":91},{"ageYears":89,"weightKg":90},32,60,{"perDose":51},[93],"G03GA02",{"status":95,"forms":96,"refs":105},"registered",[97,101],{"code":98,"en":99,"fa":100},"14731","MENOTROPINS 150IU FSH+150IU LH AMP","آمپول منوتروپینس ۱۵۰ واحد بین‌المللی FSH + ۱۵۰ واحد بین‌المللی LH",{"code":102,"en":103,"fa":104},"00804","MENOTROPINS 75 IU FSH+75IU LH AMP","آمپول منوتروپینس ۷۵ واحد بین‌المللی FSH + ۷۵ واحد بین‌المللی LH",[106],{"source":107,"section":108,"url":109},"darooyab-generic","G-2702\u002FMenotropins","https:\u002F\u002Fwww.darooyab.ir\u002FG-2702\u002FMenotropins",{"kind":111,"refs":112,"id":115},"BLA",[113],{"source":36,"section":114},"SPL approval \u002F marketing category","BLA021663",[117,120,124,127],{"kind":118,"url":119,"label":115},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=021663",{"kind":121,"url":122,"label":123},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=22c8db95-c3db-1770-8086-31356fbabe35","FDA Menopur",{"kind":125,"url":126,"label":93},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=G03GA02",{"kind":128,"url":109,"label":129},"darooyab","Menotropins",{"pregnancy":131,"lactation":139,"pediatric":148},{"level":132,"text":133,"quote":136,"refs":137},"contraindicated",{"fa":134,"en":135},"برچسب: در بارداری منع مصرف دارد.","Label: contraindicated in pregnancy.","MENOPUR is contraindicated in women who exhibit: Prior hypersensitivity to MENOPUR or menotropins products or one of their excipients High levels of FSH indicating primary ovarian failure [see Indications and Usage (1) ] Pregnancy MENOPUR may cause fetal harm when administered to a pregnant woman [see Use in Specific …",[138],{"source":36,"section":71},{"level":140,"text":141,"quote":144,"refs":145},"avoid",{"fa":142,"en":143},"برچسب: شیردهی توصیه نمی‌شود یا باید بین دارو و شیردهی یکی انتخاب شود.","Label: breastfeeding not recommended, or choose between the drug and breastfeeding.","Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in the nursing infant from MENOPUR, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.",[146],{"source":36,"section":147},"8.3",{"level":149,"text":150,"quote":153,"refs":154},"not-established",{"fa":151,"en":152},"برچسب: ایمنی و اثربخشی در کودکان ثابت نشده است.","Label: safety and effectiveness in children have not been established.","Safety and effectiveness in pediatric patients have not been established.",[155],{"source":36,"section":156},"8.4",1792444409972]