[{"data":1,"prerenderedAt":199},["ShallowReactive",2],{"drug-levofloxacin":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":21,"regimens":52,"contraindications":149,"warnings":168,"renal":169,"monitoring":170,"interactions":171,"review":172,"examples":175},"levofloxacin",1,{"fa":7,"en":8},"لووفلوکساسین","Levofloxacin","antibiotics",{"fa":11,"en":12},"فلوروکینولون","Fluoroquinolone",[14],{"name":15,"market":16},"Levaquin","US",[18,19,7,20],"levaquin","لواکین","لووفلوکسازین",[22,36,44],{"id":23,"form":24,"route":25,"label":26,"concentration":27,"markets":31,"refs":32},"tab-250","tablet","oral","250 mg tablet",{"amount":28,"unit":29,"perUnit":24,"scored":30},250,"mg",false,[16],[33],{"source":34,"section":35},"fda-levofloxacin","3",{"id":37,"form":24,"route":25,"label":38,"concentration":39,"markets":41,"refs":42},"tab-500","500 mg tablet",{"amount":40,"unit":29,"perUnit":24,"scored":30},500,[16],[43],{"source":34,"section":35},{"id":45,"form":24,"route":25,"label":46,"concentration":47,"markets":49,"refs":50},"tab-750","750 mg tablet",{"amount":48,"unit":29,"perUnit":24,"scored":30},750,[16],[51],{"source":34,"section":35},[53,71,83,95,108,119,132],{"id":54,"disease":55,"label":56,"population":59,"type":63,"unit":29,"dose":64,"refs":65,"durationDays":68},"cap","community-acquired-pneumonia",{"fa":57,"en":58},"پنومونی اکتسابی از جامعه: ۵۰۰ mg روزانه ۷ تا ۱۴ روز (یا ۷۵۰ mg، ۵ روز)","Community-acquired pneumonia: 500 mg daily 7–14 days (or 750 mg for 5 days)",{"minAge":60},{"value":61,"unit":62},18,"year","fixed",{"perDose":40,"perDoseMax":48,"dosesPerDay":5},[66],{"source":34,"section":67},"2.1, Table 1",{"min":69,"max":70},5,14,{"id":72,"disease":73,"label":74,"population":77,"type":63,"unit":29,"dose":79,"refs":80,"durationDays":82},"sinusitis","acute-bacterial-sinusitis",{"fa":75,"en":76},"سینوزیت باکتریایی حاد: ۵۰۰ mg روزانه ۱۰ تا ۱۴ روز (یا ۷۵۰ mg، ۵ روز)","Acute bacterial sinusitis: 500 mg daily 10–14 days (or 750 mg for 5 days)",{"minAge":78},{"value":61,"unit":62},{"perDose":40,"perDoseMax":48,"dosesPerDay":5},[81],{"source":34,"section":67},{"min":69,"max":70},{"id":84,"disease":84,"label":85,"population":88,"type":63,"unit":29,"dose":90,"refs":91,"durationDays":93},"aecb",{"fa":86,"en":87},"تشدید باکتریایی برونشیت مزمن: ۵۰۰ mg روزانه ۷ روز","Acute bacterial exacerbation of chronic bronchitis: 500 mg daily, 7 days",{"minAge":89},{"value":61,"unit":62},{"perDose":40,"dosesPerDay":5},[92],{"source":34,"section":67},{"min":94,"max":94},7,{"id":96,"disease":97,"label":98,"population":101,"type":63,"unit":29,"dose":103,"refs":104,"durationDays":106},"uti","urinary-tract-infection",{"fa":99,"en":100},"UTI بدون عارضه: ۲۵۰ mg روزانه ۳ روز","Uncomplicated UTI: 250 mg daily, 3 days",{"minAge":102},{"value":61,"unit":62},{"perDose":28,"dosesPerDay":5},[105],{"source":34,"section":67},{"min":107,"max":107},3,{"id":109,"disease":97,"label":110,"population":113,"type":63,"unit":29,"dose":115,"refs":116,"durationDays":118},"cuti",{"fa":111,"en":112},"UTI عارضه‌دار\u002Fپیلونفریت: ۷۵۰ mg روزانه ۵ روز","Complicated UTI\u002Fpyelonephritis: 750 mg daily, 5 days",{"minAge":114},{"value":61,"unit":62},{"perDose":48,"dosesPerDay":5},[117],{"source":34,"section":67},{"min":69,"max":69},{"id":120,"disease":121,"label":122,"population":125,"type":63,"unit":29,"dose":127,"refs":128,"durationDays":130},"sssi","skin-soft-tissue-infection",{"fa":123,"en":124},"عفونت پوست بدون عارضه: ۵۰۰ mg روزانه ۷ تا ۱۰ روز","Uncomplicated skin infection: 500 mg daily, 7–10 days",{"minAge":126},{"value":61,"unit":62},{"perDose":40,"dosesPerDay":5},[129],{"source":34,"section":67},{"min":94,"max":131},10,{"id":133,"disease":55,"label":134,"population":137,"type":139,"unit":29,"dose":140,"refs":144},"peds",{"fa":135,"en":136},"کودکان","Children",{"maxAge":138},{"value":61,"unit":62},"notCalculated",{"reason":141},{"fa":142,"en":143},"در کودکان فقط برای سیاه‌زخم استنشاقی و طاعون (۶ ماه به بالا) تأیید شده؛ قرص فقط برای ۳۰ kg به بالا.","In children approved only for inhalational anthrax and plague (≥6 months); tablets only for ≥30 kg.",[145,147],{"source":34,"section":146},"8.4",{"source":34,"section":148},"2",[150,159],{"id":151,"severity":152,"text":153,"refs":156},"ci","block",{"fa":154,"en":155},"حساسیت به لووفلوکساسین یا سایر کینولون‌ها.","Hypersensitivity to levofloxacin or other quinolones.",[157],{"source":34,"section":158},"4",{"id":160,"severity":161,"text":162,"refs":165},"boxed","warn",{"fa":163,"en":164},"هشدار جعبه‌ای: تاندونیت و پارگی تاندون، نوروپاتی محیطی، اثرات CNS و تشدید میاستنی گراویس؛ در میاستنی پرهیز شود.","Boxed warning: tendinitis and tendon rupture, peripheral neuropathy, CNS effects and exacerbation of myasthenia gravis; avoid in myasthenia gravis.",[166],{"source":34,"section":167},"Boxed Warning",[],[],[],[],{"status":173,"reviewer":174,"date":174},"unverified",null,[176,181,185,189,193,196],{"regimen":54,"formulation":37,"input":177,"expect":180},{"ageYears":178,"weightKg":179},50,70,{"perDose":40},{"regimen":72,"formulation":37,"input":182,"expect":184},{"ageYears":183,"weightKg":179},40,{"perDose":40},{"regimen":84,"formulation":37,"input":186,"expect":188},{"ageYears":187,"weightKg":179},60,{"perDose":40},{"regimen":96,"formulation":23,"input":190,"expect":192},{"ageYears":191,"weightKg":187},30,{"perDose":28},{"regimen":109,"formulation":45,"input":194,"expect":195},{"ageYears":183,"weightKg":179},{"perDose":48},{"regimen":120,"formulation":37,"input":197,"expect":198},{"ageYears":183,"weightKg":179},{"perDose":40},1792078537012]