[{"data":1,"prerenderedAt":220},["ShallowReactive",2],{"drug-iron-sucrose":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":22,"regimens":36,"contraindications":113,"warnings":123,"renal":124,"monitoring":125,"interactions":126,"review":127,"examples":130,"atc":147,"iran":149,"links":161,"populations":180,"usApproval":215},"iron-sucrose",1,{"fa":7,"en":8},"آهن سوکروز (ونوفر)","Iron sucrose (Venofer)","blood",{"fa":11,"en":12},"آهن تزریقی","Parenteral iron",[14],{"name":15,"market":16},"Venofer","US",[18,19,20,21],"venofer","ونوفر","آهن وریدی","آیرون سوکروز",[23],{"id":24,"form":25,"route":26,"label":27,"concentration":28,"markets":31,"refs":32},"vial-20","injection","iv","20 mg iron\u002FmL (50, 100 or 200 mg vial)",{"amount":29,"unit":30,"perVolumeMl":5},20,"mg",[16],[33],{"source":34,"section":35},"fda-venofer","3",[37,67,84],{"id":38,"disease":39,"label":40,"population":43,"type":47,"unit":30,"dose":48,"refs":50,"notes":53},"hdd","anemia-ckd",{"fa":41,"en":42},"کم‌خونی فقر آهن در همودیالیز — ۱۰۰ mg در هر جلسه دیالیز (مجموع ۱۰۰۰ mg)","Iron deficiency on haemodialysis — 100 mg per dialysis session (course 1,000 mg)",{"minAge":44},{"value":45,"unit":46},18,"year","fixed",{"perDose":49,"dosesPerDay":5},100,[51],{"source":34,"section":52},"2.2",[54,60],{"text":55,"refs":58},{"fa":56,"en":57},"تزریق بدون رقیق‌سازی در ۲ تا ۵ دقیقه یا انفوزیون در ۱۰۰ mL سالین در ۱۵ دقیقه، اوایل دیالیز.","Undiluted over 2–5 min or infusion in 100 mL saline over 15 min, early in dialysis.",[59],{"source":34,"section":52},{"text":61,"refs":64},{"fa":62,"en":63},"دوز بر حسب آهن المنتال. فقط وریدی (تزریق آهسته یا انفوزیون).","Dose is elemental iron. IV only (slow injection or infusion).",[65],{"source":34,"section":66},"2.1",{"id":68,"disease":39,"label":69,"population":72,"type":47,"unit":30,"dose":74,"refs":76,"notes":79},"ndd",{"fa":70,"en":71},"بیماری مزمن کلیه بدون دیالیز — ۲۰۰ mg در ۵ نوبت طی ۱۴ روز","Non-dialysis CKD — 200 mg on 5 occasions within 14 days",{"minAge":73},{"value":45,"unit":46},{"perDose":75,"dosesPerDay":5},200,[77],{"source":34,"section":78},"2.3",[80],{"text":81,"refs":82},{"fa":62,"en":63},[83],{"source":34,"section":66},{"id":85,"disease":39,"label":86,"population":89,"type":93,"unit":30,"dose":94,"refs":96,"limits":99,"notes":102},"child",{"fa":87,"en":88},"کودک ۲ سال به بالا در دیالیز (نگهدارنده) — ۰٫۵ mg\u002Fkg هر ۲ هفته","Child ≥2 y on dialysis (maintenance) — 0.5 mg\u002Fkg every 2 weeks",{"minAge":90,"maxAge":92},{"value":91,"unit":46},2,{"value":45,"unit":46},"weightBased",{"perKgPerDay":95,"dividedDoses":5},0.5,[97],{"source":34,"section":98},"2.5",{"maxPerDose":49,"refs":100},[101],{"source":34,"section":98},[103,109],{"text":104,"refs":107},{"fa":105,"en":106},"هر ۲ هفته به مدت ۱۲ هفته (نه روزانه). درمان جایگزینی در کودک ثابت نشده.","Every 2 weeks for 12 weeks (not daily). Replacement dosing in children not established.",[108],{"source":34,"section":98},{"text":110,"refs":111},{"fa":62,"en":63},[112],{"source":34,"section":66},[114],{"id":115,"severity":116,"text":117,"refs":120},"hyper","block",{"fa":118,"en":119},"حساسیت به ونوفر.","Hypersensitivity to Venofer.",[121],{"source":34,"section":122},"4",[],[],[],[],{"status":128,"reviewer":129,"date":129},"unverified",null,[131,137,141],{"regimen":38,"formulation":24,"input":132,"expect":135},{"ageYears":133,"weightKg":134},60,70,{"perDose":49,"mlPerDose":136},5,{"regimen":68,"formulation":24,"input":138,"expect":139},{"ageYears":133,"weightKg":134},{"perDose":75,"mlPerDose":140},10,{"regimen":85,"formulation":24,"input":142,"expect":144},{"ageYears":140,"weightKg":143},30,{"perDose":145,"mlPerDose":146},15,0.75,[148],"B03AC",{"status":150,"forms":151,"refs":156},"registered",[152],{"code":153,"en":154,"fa":155},"04003","IRON SUCROSE 20 MGFE\u002FML 5ML AMP","آمپول آهن سوکروس ۲۰ مگف \u002F میلی‌لیتر ۵ میلی‌لیتر",[157],{"source":158,"section":159,"url":160},"darooyab-generic","G-2899\u002FIron-Sucrose","https:\u002F\u002Fwww.darooyab.ir\u002FG-2899\u002FIron-Sucrose",[162,166,170,174,177],{"kind":163,"url":164,"label":165},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=021135","NDA021135",{"kind":167,"url":168,"label":169},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=626dc9e5-c6b4-4f9c-9bf4-774fd3ae619a","FDA Venofer",{"kind":171,"url":172,"label":173},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa614017.html","Iron Sucrose Injection",{"kind":175,"url":176,"label":148},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=B03AC",{"kind":178,"url":160,"label":179},"darooyab","Iron-Sucrose",{"pregnancy":181,"lactation":190,"pediatric":198,"geriatric":207},{"level":182,"text":183,"quote":186,"refs":187},"caution",{"fa":184,"en":185},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary Published studies on intravenous iron sucrose treatment after the first trimester of pregnancy have not shown adverse maternal or fetal outcomes (see Data) .",[188],{"source":34,"section":189},"8.1",{"level":182,"text":191,"quote":194,"refs":195},{"fa":192,"en":193},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary Iron sucrose is present in human milk, and available published reports following exposure to 100-300 mg intravenous iron sucrose have not reported adverse reactions in breastfed infants (see Data) .",[196],{"source":34,"section":197},"8.2",{"level":199,"text":200,"quote":203,"refs":204},"not-established",{"fa":201,"en":202},"برچسب: ایمنی و اثربخشی در کودکان ثابت نشده است.","Label: safety and effectiveness in children have not been established.","Safety and effectiveness of Venofer for iron replacement treatment in pediatric patients with dialysis-dependent or non-dialysis-dependent CKD have not been established.",[205],{"source":34,"section":206},"8.4",{"level":182,"text":208,"quote":211,"refs":212},{"fa":209,"en":210},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","In general, dose administration to an elderly patient should be cautious, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.",[213],{"source":34,"section":214},"8.5",{"kind":216,"refs":217,"id":165},"NDA",[218],{"source":34,"section":219},"SPL approval \u002F marketing category",1792111457589]