[{"data":1,"prerenderedAt":152},["ShallowReactive",2],{"drug-ibandronate":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":21,"regimens":36,"contraindications":59,"warnings":69,"renal":70,"monitoring":80,"interactions":81,"review":82,"examples":85,"atc":86,"iran":88,"links":95,"populations":113,"usApproval":147},"ibandronate",1,{"fa":7,"en":8},"ایباندرونات","Ibandronate","musculoskeletal",{"fa":11,"en":12},"بیس‌فسفونات","Bisphosphonate",[14],{"name":15,"market":16},"Boniva","US",[18,19,20],"boniva","بونیوا","ایباندرونیک اسید",[22],{"id":23,"form":24,"route":25,"label":26,"concentration":27,"markets":31,"refs":32},"tab-150","tablet","oral","150 mg tablet",{"amount":28,"unit":29,"perUnit":24,"scored":30},150,"mg",false,[16],[33],{"source":34,"section":35},"fda-ibandronate","3",[37],{"id":38,"disease":39,"label":40,"population":43,"type":47,"unit":29,"dose":48,"refs":52},"op","osteoporosis",{"fa":41,"en":42},"پوکی استخوان پس از یائسگی — ۱۵۰ mg ماهی یک بار","Postmenopausal osteoporosis — 150 mg once MONTHLY",{"minAge":44},{"value":45,"unit":46},18,"year","notCalculated",{"reason":49},{"fa":50,"en":51},"ماهی یک بار (نه روزانه) در یک تاریخ ثابت. ناشتا با یک لیوان پر آب ساده، دست‌کم ۶۰ دقیقه پیش از غذا، نوشیدنی یا داروی دیگر؛ تا ۶۰ دقیقه دراز نکشد؛ قرص جویده یا مکیده نشود. کلسیم و ویتامین D کافی.","Once MONTHLY (not daily) on the same date. Fasting with a full glass of plain water, at least 60 min before food, drink or other drugs; stay upright for 60 min; do not chew or suck. Adequate calcium and vitamin D.",[53,55,57],{"source":34,"section":54},"2.1",{"source":34,"section":56},"2.2",{"source":34,"section":58},"2.3",[60],{"id":61,"severity":62,"text":63,"refs":66},"ci","block",{"fa":64,"en":65},"ناهنجاری مری که تخلیه آن را به تأخیر می‌اندازد (تنگی، آشالازی)؛ ناتوانی در ایستادن یا نشستن صاف به مدت ۶۰ دقیقه؛ هیپوکلسمی؛ حساسیت.","Oesophageal abnormalities delaying emptying (stricture, achalasia); inability to stand or sit upright for 60 min; hypocalcaemia; hypersensitivity.",[67],{"source":34,"section":68},"4",[],[71],{"egfrBelow":72,"severity":73,"text":74,"refs":77},30,"warn",{"fa":75,"en":76},"کلیرانس کراتینین زیر ۳۰: توصیه نمی‌شود.","CrCl \u003C30 mL\u002Fmin: not recommended.",[78],{"source":34,"section":79},"8.6",[],[],{"status":83,"reviewer":84,"date":84},"unverified",null,[],[87],"M05BA06",{"status":89,"refs":90},"not-found",[91],{"source":92,"section":93,"url":94},"darooyab-generic","search","https:\u002F\u002Fwww.darooyab.ir\u002FSearch?q=Ibandronate",[96,100,104,107,110],{"kind":97,"url":98,"label":99},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=078998","ANDA078998",{"kind":101,"url":102,"label":103},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=6ca94cce-a2bb-421f-bd8f-6b14bc2bd985","FDA Ibandronate",{"kind":105,"url":106,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa605035.html",{"kind":105,"url":108,"label":109},"https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa607032.html","Ibandronate Injection",{"kind":111,"url":112,"label":87},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=M05BA06",{"pregnancy":114,"lactation":123,"pediatric":130,"geriatric":139},{"level":115,"text":116,"quote":119,"refs":120},"caution",{"fa":117,"en":118},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary Ibandronate sodium is not indicated for use in women of reproductive potential.",[121],{"source":34,"section":122},"8.1",{"level":115,"text":124,"quote":119,"refs":127},{"fa":125,"en":126},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.",[128],{"source":34,"section":129},"8.2",{"level":131,"text":132,"quote":135,"refs":136},"not-established",{"fa":133,"en":134},"برچسب: ایمنی و اثربخشی در کودکان ثابت نشده است.","Label: safety and effectiveness in children have not been established.","Safety and effectiveness in pediatric patients have not been established.",[137],{"source":34,"section":138},"8.4",{"level":115,"text":140,"quote":143,"refs":144},{"fa":141,"en":142},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Of the patients receiving ibandronate sodium 150 mg once-monthly in the postmenopausal osteoporosis 1 year study, 52% were over 65 years of age, and 9% were over 75 years of age.",[145],{"source":34,"section":146},"8.5",{"kind":148,"refs":149,"id":99},"ANDA",[150],{"source":34,"section":151},"SPL approval \u002F marketing category",1792156181723]