[{"data":1,"prerenderedAt":104},["ShallowReactive",2],{"drug-hydroxocobalamin":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":25,"regimens":39,"contraindications":77,"warnings":87,"renal":88,"monitoring":89,"interactions":90,"review":91,"examples":94},"hydroxocobalamin",1,{"fa":7,"en":8},"هیدروکسوکوبالامین (ویتامین B12)","Hydroxocobalamin (vitamin B12)","nutrition",{"fa":11,"en":12},"ویتامین B12 تزریقی","Injectable vitamin B12",[14],{"name":15,"market":16},"Cobalin-H","GB",[18,19,20,21,22,23,24],"vitamin b12","b12","ب ۱۲","آمپول ب۱۲","ویتامین ب12","cobalamin","سیانوکوبالامین",[26],{"id":27,"form":28,"route":29,"label":30,"concentration":31,"markets":34,"refs":35},"inj-1000","injection","im","1,000 mcg\u002FmL (1 mg\u002FmL) injection",{"amount":32,"unit":33,"perVolumeMl":5},1000,"mcg",[16],[36],{"source":37,"section":38},"uk-smpc-hydroxocobalamin","2",[40,60],{"id":41,"disease":42,"label":43,"population":46,"type":47,"unit":33,"dose":48,"refs":50,"notes":53},"pa","b12-deficiency",{"fa":44,"en":45},"کم‌خونی پرنیشیوز بدون درگیری عصبی: ۱۰۰۰ mcg عضلانی یک روز در میان (۱ تا ۲ هفته)","Pernicious anaemia without neurological involvement: 1,000 mcg IM on alternate days (1–2 weeks)",{},"fixed",{"perDose":32,"dosesPerDay":5,"intervalHours":49},48,[51],{"source":37,"section":52},"4.2",[54],{"text":55,"refs":58},{"fa":56,"en":57},"شروع ۲۵۰ تا ۱۰۰۰ mcg یک روز در میان ۱ تا ۲ هفته، سپس ۲۵۰ mcg هفتگی تا طبیعی شدن شمارش؛ نگهدارنده ۱۰۰۰ mcg هر ۲ تا ۳ ماه. با درگیری عصبی: ۱۰۰۰ mcg یک روز در میان تا وقتی بهبود ادامه دارد. برای بزرگسال و کودک.","Initially 250–1,000 mcg on alternate days for 1–2 weeks, then 250 mcg weekly until counts normal; maintenance 1,000 mcg every 2–3 months. With neurological involvement: 1,000 mcg alternate days while improving. Adults and children.",[59],{"source":37,"section":52},{"id":61,"disease":42,"label":62,"population":65,"type":47,"unit":33,"dose":66,"refs":67,"durationDays":69,"notes":70},"maint",{"fa":63,"en":64},"نگهدارنده یا پیشگیری (گاسترکتومی، سوءجذب، گیاه‌خواری مطلق): ۱۰۰۰ mcg هر ۲ تا ۳ ماه","Maintenance or prophylaxis (gastrectomy, malabsorption, strict vegans): 1,000 mcg every 2–3 months",{},{"perDose":32,"dosesPerDay":5},[68],{"source":37,"section":52},{"min":5,"max":5},[71],{"text":72,"refs":75},{"fa":73,"en":74},"یک تزریق؛ هر ۲ تا ۳ ماه تکرار.","One injection; repeat every 2–3 months.",[76],{"source":37,"section":52},[78],{"id":79,"severity":80,"text":81,"refs":84},"ci","block",{"fa":82,"en":83},"حساسیت.","Hypersensitivity.",[85],{"source":37,"section":86},"4.3",[],[],[],[],{"status":92,"reviewer":93,"date":93},"unverified",null,[95,100],{"regimen":41,"formulation":27,"input":96,"expect":99},{"ageYears":97,"weightKg":98},60,70,{"perDose":32,"mlPerDose":5},{"regimen":61,"formulation":27,"input":101,"expect":103},{"ageYears":102,"weightKg":98},40,{"mlPerDose":5},1792078536127]