[{"data":1,"prerenderedAt":165},["ShallowReactive",2],{"drug-gemfibrozil":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":22,"regimens":37,"contraindications":54,"warnings":64,"renal":65,"monitoring":66,"interactions":67,"review":84,"examples":87,"atc":93,"iran":95,"links":115,"populations":132,"usApproval":160},"gemfibrozil",1,{"fa":7,"en":8},"جم‌فیبروزیل","Gemfibrozil","cardiovascular",{"fa":11,"en":12},"فیبرات","Fibrate",[14],{"name":15,"market":16},"Lopid","US",[18,19,20,21],"lopid","لوپید","جمفیبروزیل","تری گلیسرید",[23],{"id":24,"form":25,"route":26,"label":27,"concentration":28,"markets":32,"refs":33},"tab-600","tablet","oral","600 mg tablet (scored)",{"amount":29,"unit":30,"perUnit":25,"scored":31},600,"mg",true,[16],[34],{"source":35,"section":36},"fda-gemfibrozil","How Supplied",[38],{"id":39,"disease":40,"label":41,"population":44,"type":48,"unit":30,"dose":49,"refs":51},"tg","hypertriglyceridemia",{"fa":42,"en":43},"تری‌گلیسرید بالا — ۶۰۰ mg دو بار، ۳۰ دقیقه پیش از صبحانه و شام","High triglycerides — 600 mg twice daily, 30 min before breakfast and dinner",{"minAge":45},{"value":46,"unit":47},18,"year","fixed",{"perDose":29,"dosesPerDay":50},2,[52],{"source":35,"section":53},"Dosage and Administration",[55],{"id":56,"severity":57,"text":58,"refs":61},"ci","block",{"fa":59,"en":60},"اختلال کبد یا کلیه شدید (از جمله سیروز صفراوی)؛ بیماری کیسه صفرا؛ حساسیت؛ هم‌زمان با سیمواستاتین، رپاگلینید یا سلکسی‌پاگ.","Hepatic or severe renal dysfunction (incl. primary biliary cirrhosis); gallbladder disease; hypersensitivity; with simvastatin, repaglinide or selexipag.",[62],{"source":35,"section":63},"Contraindications",[],[],[],[68,76],{"with":69,"text":70,"refs":73},"statins",{"fa":71,"en":72},"با استاتین‌ها خطر میوپاتی و رابدومیولیز.","With statins: myopathy and rhabdomyolysis.",[74],{"source":35,"section":75},"Warnings",{"with":77,"text":78,"refs":81},"warfarin",{"fa":79,"en":80},"اثر وارفارین را زیاد می‌کند.","Potentiates warfarin.",[82],{"source":35,"section":83},"Precautions",{"status":85,"reviewer":86,"date":86},"unverified",null,[88],{"regimen":39,"formulation":24,"input":89,"expect":92},{"ageYears":90,"weightKg":91},50,85,{"perDose":29,"tabletsPerDoseRounded":5},[94],"C10AB04",{"status":96,"forms":97,"refs":110},"registered",[98,102,106],{"code":99,"en":100,"fa":101},"00584","GEMFIBROZIL 300MG CAP","کپسول جم‌فیبروزیل ۳۰۰ میلی‌گرم",{"code":103,"en":104,"fa":105},"01520","GEMFIBROZIL 450MG TAB","قرص جم‌فیبروزیل ۴۵۰ میلی‌گرم",{"code":107,"en":108,"fa":109},"12739","GEMFIBROZIL 600MG  TAB","قرص جم‌فیبروزیل ۶۰۰ میلی‌گرم",[111],{"source":112,"section":113,"url":114},"darooyab-generic","G-1692\u002FGemfibrozil","https:\u002F\u002Fwww.darooyab.ir\u002FG-1692\u002FGemfibrozil",[116,120,124,127,130],{"kind":117,"url":118,"label":119},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=079072","ANDA079072",{"kind":121,"url":122,"label":123},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=75cac02c-56e3-4dfe-b1e2-4ce166b28833","FDA Gemfibrozil",{"kind":125,"url":126,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa686002.html",{"kind":128,"url":129,"label":94},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=C10AB04",{"kind":131,"url":114,"label":8},"darooyab",{"pregnancy":133,"lactation":142,"pediatric":151},{"level":134,"text":135,"quote":138,"refs":139},"caution",{"fa":136,"en":137},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Gemfibrozil should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.",[140],{"source":35,"section":141},"Precautions\u002FWarnings – Pregnancy",{"level":143,"text":144,"quote":147,"refs":148},"avoid",{"fa":145,"en":146},"برچسب: شیردهی توصیه نمی‌شود یا باید بین دارو و شیردهی یکی انتخاب شود.","Label: breastfeeding not recommended, or choose between the drug and breastfeeding.","Because many drugs are excreted in human milk and because of the potential for tumorigenicity shown for gemfibrozil in animal studies, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. 7.",[149],{"source":35,"section":150},"Precautions\u002FWarnings – Nursing Mothers",{"level":152,"text":153,"quote":156,"refs":157},"not-established",{"fa":154,"en":155},"برچسب: ایمنی و اثربخشی در کودکان ثابت نشده است.","Label: safety and effectiveness in children have not been established.","Safety and efficacy in pediatric patients have not been established.",[158],{"source":35,"section":159},"Precautions\u002FWarnings – Pediatric Use",{"kind":161,"refs":162,"id":119},"ANDA",[163],{"source":35,"section":164},"SPL approval \u002F marketing category",1792100108426]