[{"data":1,"prerenderedAt":161},["ShallowReactive",2],{"drug-etomidate":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":19,"regimens":33,"contraindications":68,"warnings":78,"renal":79,"monitoring":80,"interactions":81,"review":82,"examples":85,"atc":94,"iran":96,"usApproval":108,"links":114,"populations":127},"etomidate",1,{"fa":7,"en":8},"اتومیدیت","Etomidate","nervous-system",{"fa":11,"en":12},"بیهوش‌کننده وریدی","IV general anaesthetic",[14],{"name":15,"market":16},"Amidate","US",[18,7],"amidate",[20],{"id":21,"form":22,"route":23,"label":24,"concentration":25,"markets":28,"refs":29},"inj-2","injection","iv","2 mg\u002FmL (20 mg\u002F10 mL, 40 mg\u002F20 mL)",{"amount":26,"unit":27,"perVolumeMl":5},2,"mg",[16],[30],{"source":31,"section":32},"fda-amidate","How Supplied",[34],{"id":35,"disease":36,"label":37,"population":40,"type":44,"unit":27,"dose":45,"refs":49,"durationDays":52,"notes":53},"ind","general-anesthesia",{"fa":38,"en":39},"القای بیهوشی — بزرگسال و کودک بالای ۱۰ سال: معمولاً ۰٫۳ mg\u002Fkg (۰٫۲ تا ۰٫۶) در ۳۰ تا ۶۰ ثانیه","Induction — adults and children >10 y: usually 0.3 mg\u002Fkg (0.2–0.6) over 30–60 s",{"minAge":41},{"value":42,"unit":43},10,"year","weightBased",{"perKgPerDose":46,"perKgPerDoseMax":47,"intervalHours":48},0.3,0.6,24,[50],{"source":31,"section":51},"Dosage and Administration",{"min":5,"max":5},[54,61],{"text":55,"refs":58},{"fa":56,"en":57},"فقط توسط فرد آموزش‌دیده در بیهوشی با امکانات کنترل راه هوایی، اکسیژن و احیا.","Only by persons trained in anaesthesia, with airway management, oxygen and resuscitation available.",[59],{"source":31,"section":60},"Warnings",{"text":62,"refs":65},{"fa":63,"en":64},"زیر ۱۰ سال داده کافی نیست و توصیه نمی‌شود. سالمندان ممکن است دوز کمتری بخواهند. برای انفوزیون طولانی نه (سرکوب کورتیزول و آلدوسترون).","Insufficient data under 10 y — not recommended. Elderly may need less. Not for prolonged infusion (suppresses cortisol and aldosterone).",[66,67],{"source":31,"section":51},{"source":31,"section":60},[69],{"id":70,"severity":71,"text":72,"refs":75},"hyper","block",{"fa":73,"en":74},"حساسیت به اتومیدیت.","Hypersensitivity to etomidate.",[76],{"source":31,"section":77},"Contraindications",[],[],[],[],{"status":83,"reviewer":84,"date":84},"unverified",null,[86],{"regimen":35,"formulation":21,"input":87,"expect":90},{"ageYears":88,"weightKg":89},40,70,{"perDose":91,"mlPerDose":92,"upperPerDose":93},21,10.5,42,[95],"N01AX07",{"status":97,"forms":98,"refs":103},"registered",[99],{"code":100,"en":101,"fa":102},"01501","ETOMIDATE 20MG\u002F10ML AMP","آمپول اتومیدات ۲۰ میلی‌گرم \u002F ۱۰ میلی‌لیتر",[104],{"source":105,"section":106,"url":107},"darooyab-generic","G-2668\u002FEtomidate","https:\u002F\u002Fwww.darooyab.ir\u002FG-2668\u002FEtomidate",{"kind":109,"refs":110,"id":113},"NDA",[111],{"source":31,"section":112},"SPL approval \u002F marketing category","NDA018227",[115,118,122,125],{"kind":116,"url":117,"label":113},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=018227",{"kind":119,"url":120,"label":121},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=b7ed5bf8-ba75-44dc-8f81-96b4ad5766be","FDA Amidate",{"kind":123,"url":124,"label":95},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=N01AX07",{"kind":126,"url":107,"label":8},"darooyab",{"pregnancy":128,"lactation":137,"pediatric":145,"geriatric":153},{"level":129,"text":130,"quote":133,"refs":134},"caution",{"fa":131,"en":132},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary There are no adequate and well-controlled studies in pregnant women.",[135],{"source":31,"section":136},"Pregnancy",{"level":129,"text":138,"quote":141,"refs":142},{"fa":139,"en":140},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Because many drugs are excreted in human milk, caution should be exercised when AMIDATE is administered to a nursing mother.",[143],{"source":31,"section":144},"Nursing Mothers",{"level":129,"text":146,"quote":149,"refs":150},{"fa":147,"en":148},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","There are inadequate data for AMIDATE to make dosage recommendations for induction of anesthesia in patients below the age of ten (10) years; therefore, such use is not recommended (see also DOSAGE AND ADMINISTRATION ).",[151],{"source":31,"section":152},"Pediatric Use",{"level":129,"text":154,"quote":157,"refs":158},{"fa":155,"en":156},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Elderly patients may require lower doses of AMIDATE than younger patients.",[159],{"source":31,"section":160},"Geriatric Use",1792156177853]