[{"data":1,"prerenderedAt":238},["ShallowReactive",2],{"drug-enoxaparin":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":20,"formulations":24,"regimens":52,"contraindications":101,"warnings":111,"renal":119,"monitoring":120,"interactions":121,"review":122,"examples":125,"atc":137,"iran":139,"links":179,"populations":198,"usApproval":233},"enoxaparin",1,{"fa":7,"en":8},"انوکساپارین","Enoxaparin","blood",{"fa":11,"en":12},"هپارین با وزن مولکولی کم","Low-molecular-weight heparin",[14,17],{"name":15,"market":16},"Lovenox","US",{"name":18,"market":19},"Clexane","GB",[21,22,23,7],"clexane","lovenox","کلکسان",[25,38,45],{"id":26,"form":27,"route":28,"label":29,"concentration":30,"markets":33,"refs":34},"syr-40","injection","sc","40 mg\u002F0.4 mL prefilled syringe (100 mg\u002FmL)",{"amount":31,"unit":32,"perVolumeMl":5},100,"mg",[16],[35],{"source":36,"section":37},"fda-enoxaparin","3",{"id":39,"form":27,"route":28,"label":40,"concentration":41,"markets":42,"refs":43},"syr-60","60 mg\u002F0.6 mL prefilled syringe (100 mg\u002FmL)",{"amount":31,"unit":32,"perVolumeMl":5},[16],[44],{"source":36,"section":37},{"id":46,"form":27,"route":28,"label":47,"concentration":48,"markets":49,"refs":50},"syr-80","80 mg\u002F0.8 mL prefilled syringe (100 mg\u002FmL)",{"amount":31,"unit":32,"perVolumeMl":5},[16],[51],{"source":36,"section":37},[53,80],{"id":54,"disease":55,"label":56,"population":59,"type":63,"unit":32,"dose":64,"refs":66,"durationDays":69,"notes":72},"proph","dvt-prophylaxis",{"fa":57,"en":58},"پیشگیری در بیمار بستری بی‌تحرک — ۴۰ mg زیرجلدی روزانه","Prophylaxis in immobile medical patients — 40 mg SC daily",{"minAge":60},{"value":61,"unit":62},18,"year","fixed",{"perDose":65,"dosesPerDay":5},40,[67],{"source":36,"section":68},"2.2",{"min":70,"max":71},6,11,[73],{"text":74,"refs":77},{"fa":75,"en":76},"کلیرانس کراتینین زیر ۳۰: ۳۰ mg روزانه.","CrCl \u003C30 mL\u002Fmin: 30 mg once daily.",[78],{"source":36,"section":79},"2.3, Table 1",{"id":81,"disease":82,"label":83,"population":86,"type":88,"unit":32,"dose":89,"refs":91,"notes":93},"dvt","venous-thromboembolism",{"fa":84,"en":85},"درمان DVT (سرپایی) — ۱ mg\u002Fkg زیرجلدی هر ۱۲ ساعت","DVT treatment (outpatient) — 1 mg\u002Fkg SC every 12 h",{"minAge":87},{"value":61,"unit":62},"weightBased",{"perKgPerDose":5,"intervalHours":90},12,[92],{"source":36,"section":68},[94],{"text":95,"refs":98},{"fa":96,"en":97},"هم‌زمان با وارفارین تا INR ۲ تا ۳ (حداقل ۵ روز). کلیرانس کراتینین زیر ۳۰: ۱ mg\u002Fkg یک بار در روز.","With warfarin until INR 2–3 (at least 5 days). CrCl \u003C30 mL\u002Fmin: 1 mg\u002Fkg once daily.",[99,100],{"source":36,"section":68},{"source":36,"section":79},[102],{"id":103,"severity":104,"text":105,"refs":108},"ci","block",{"fa":106,"en":107},"خونریزی فعال عمده؛ سابقه HIT در ۱۰۰ روز اخیر؛ حساسیت به انوکساپارین، هپارین یا فرآورده خوکی.","Active major bleeding; HIT within the past 100 days; hypersensitivity to enoxaparin, heparin or pork products.",[109],{"source":36,"section":110},"4",[112],{"text":113,"refs":116},{"fa":114,"en":115},"هشدار جعبه‌ای: هماتوم نخاعی\u002Fاپیدورال با بی‌حسی نخاعی یا پونکسیون — خطر فلج.","Boxed warning: spinal\u002Fepidural haematoma with neuraxial anaesthesia or puncture — risk of paralysis.",[117],{"source":36,"section":118},"Boxed Warning",[],[],[],{"status":123,"reviewer":124,"date":124},"unverified",null,[126,132],{"regimen":54,"formulation":26,"input":127,"expect":130},{"ageYears":128,"weightKg":129},60,70,{"perDose":65,"mlPerDose":131},0.4,{"regimen":81,"formulation":46,"input":133,"expect":135},{"ageYears":134,"weightKg":129},50,{"perDose":129,"mlPerDose":136},0.7,[138],"B01AB05",{"status":140,"forms":141,"refs":174},"registered",[142,146,150,154,158,162,166,170],{"code":143,"en":144,"fa":145},"17725","ENOXAPARIN 100MG\u002FML (10,000 U) 1ML AMP","آمپول انوکساپارین ۱۰۰ میلی‌گرم \u002F میلی‌لیتر (۱۰۰۰۰ واحد) ۱ میلی‌لیتر",{"code":147,"en":148,"fa":149},"02295","ENOXAPARIN 100MG\u002FML (10,000 U) 1ML SYRINGE","سرنگ انوکساپارین ۱۰۰ میلی‌گرم \u002F میلی‌لیتر (۱۰۰۰۰ واحد) ۱ میلی‌لیتر",{"code":151,"en":152,"fa":153},"02294","ENOXAPARIN 100MG\u002FML (2,000 U) 0.2ML SYRINGE","سرنگ انوکساپارین ۱۰۰ میلی‌گرم \u002F میلی‌لیتر (۲۰۰۰ واحد) ۰٫۲ میلی‌لیتر",{"code":155,"en":156,"fa":157},"22180","ENOXAPARIN 100MG\u002FML (4,000 U) 0.4ML AMP","آمپول انوکساپارین ۱۰۰ میلی‌گرم \u002F میلی‌لیتر (۴۰۰۰ واحد) ۰٫۴ میلی‌لیتر",{"code":159,"en":160,"fa":161},"02043","ENOXAPARIN 100MG\u002FML (4,000 U) 0.4ML SYRINGE","سرنگ انوکساپارین ۱۰۰ میلی‌گرم \u002F میلی‌لیتر (۴۰۰۰ واحد) ۰٫۴ میلی‌لیتر",{"code":163,"en":164,"fa":165},"17723","ENOXAPARIN 100MG\u002FML (6,000 U) 0.6ML AMP","آمپول انوکساپارین ۱۰۰ میلی‌گرم \u002F میلی‌لیتر (۶۰۰۰ واحد) ۰٫۶ میلی‌لیتر",{"code":167,"en":168,"fa":169},"02292","ENOXAPARIN 100MG\u002FML (6,000 U) 0.6ML SYRINGE","سرنگ انوکساپارین ۱۰۰ میلی‌گرم \u002F میلی‌لیتر (۶۰۰۰ واحد) ۰٫۶ میلی‌لیتر",{"code":171,"en":172,"fa":173},"02293","ENOXAPARIN 100MG\u002FML (8,000 U) 0.8ML SYRINGE","سرنگ انوکساپارین ۱۰۰ میلی‌گرم \u002F میلی‌لیتر (۸۰۰۰ واحد) ۰٫۸ میلی‌لیتر",[175],{"source":176,"section":177,"url":178},"darooyab-generic","G-1661\u002FEnoxaparin-Sodium","https:\u002F\u002Fwww.darooyab.ir\u002FG-1661\u002FEnoxaparin-Sodium",[180,184,188,192,195],{"kind":181,"url":182,"label":183},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=076684","ANDA076684",{"kind":185,"url":186,"label":187},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=9e2875df-0f0c-46ec-990f-69108f383f58","FDA Enoxaparin",{"kind":189,"url":190,"label":191},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa601210.html","Enoxaparin Injection",{"kind":193,"url":194,"label":138},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=B01AB05",{"kind":196,"url":178,"label":197},"darooyab","Enoxaparin-Sodium",{"pregnancy":199,"lactation":208,"pediatric":216,"geriatric":225},{"level":200,"text":201,"quote":204,"refs":205},"caution",{"fa":202,"en":203},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary Placental transfer of enoxaparin was observed in the animal studies.",[206],{"source":36,"section":207},"8.1",{"level":200,"text":209,"quote":212,"refs":213},{"fa":210,"en":211},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","In lactating rats, the passage of enoxaparin or its metabolites in the milk is very limited.",[214],{"source":36,"section":215},"8.2",{"level":217,"text":218,"quote":221,"refs":222},"not-established",{"fa":219,"en":220},"برچسب: ایمنی و اثربخشی در کودکان ثابت نشده است.","Label: safety and effectiveness in children have not been established.","Safety and effectiveness of Enoxaparin Sodium Injection in pediatric patients have not been established.",[223],{"source":36,"section":224},"8.4",{"level":200,"text":226,"quote":229,"refs":230},{"fa":227,"en":228},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Monitoring of geriatric patients with low body weight (\u003C45 kg) and those predisposed to decreased renal function should be considered [ see Warnings and Precautions ( 2.6 ) and Clinical Pharmacology ( 12.3 ) ].",[231],{"source":36,"section":232},"8.5",{"kind":234,"refs":235,"id":183},"ANDA",[236],{"source":36,"section":237},"SPL approval \u002F marketing category",1792092031814]