[{"data":1,"prerenderedAt":161},["ShallowReactive",2],{"drug-drospirenone-ethinylestradiol":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":22,"regimens":35,"contraindications":51,"warnings":61,"renal":71,"monitoring":72,"interactions":73,"review":74,"examples":77,"atc":78,"iran":80,"links":100,"populations":122,"usApproval":156},"drospirenone-ethinylestradiol",1,{"fa":7,"en":8},"دروسپیرنون + اتینیل استرادیول (یاسمین)","Drospirenone + ethinyl estradiol","genitourinary-sex-hormones",{"fa":11,"en":12},"ضدبارداری خوراکی ترکیبی","Combined oral contraceptive",[14],{"name":15,"market":16},"Yasmin","US",[18,19,20,21],"yasmin","یاسمین","دروسپیرنون","قرص ضد بارداری",[23],{"id":24,"form":25,"route":26,"label":27,"concentration":28,"markets":30,"refs":31},"pack","tablet","oral","21 active tablets (3 mg drospirenone + 0.03 mg EE) + 7 inert",{"amount":5,"unit":29,"perUnit":25},"mg",[16],[32],{"source":33,"section":34},"fda-yasmin","3",[36],{"id":37,"disease":38,"label":39,"population":42,"type":43,"unit":29,"dose":44,"refs":48},"coc","contraception",{"fa":40,"en":41},"پیشگیری از بارداری — یک قرص روزانه به ترتیب بسته","Contraception — one tablet daily in pack order",{},"notCalculated",{"reason":45},{"fa":46,"en":47},"یک قرص در روز در ساعت ثابت به ترتیب بسته (۲۱ فعال + ۷ بی‌اثر).","One tablet daily at the same time in pack order (21 active + 7 inert).",[49],{"source":33,"section":50},"2",[52],{"id":53,"severity":54,"text":55,"refs":58},"ci","block",{"fa":56,"en":57},"نارسایی کلیه؛ نارسایی آدرنال؛ خطر بالای ترومبوز شریانی یا وریدی (سیگاری بالای ۳۵ سال، سابقه DVT\u002FPE، بیماری عروق مغز یا کرونر و…)؛ سرطان پستان؛ بیماری کبد؛ خونریزی رحمی تشخیص‌داده‌نشده؛ بارداری.","Renal impairment; adrenal insufficiency; high risk of arterial or venous thrombosis (smokers over 35, DVT\u002FPE history, cerebrovascular or coronary disease, etc.); breast cancer; liver disease; undiagnosed uterine bleeding; pregnancy.",[59],{"source":33,"section":60},"4",[62],{"text":63,"refs":66},{"fa":64,"en":65},"هشدار جعبه‌ای: سیگار خطر حوادث قلبی‌عروقی را بالا می‌برد، به‌ویژه بالای ۳۵ سال. دروسپیرنون پتاسیم را بالا می‌برد.","Boxed warning: smoking raises the risk of serious cardiovascular events, especially over 35. Drospirenone can raise potassium.",[67,69],{"source":33,"section":68},"Boxed Warning",{"source":33,"section":70},"5",[],[],[],{"status":75,"reviewer":76,"date":76},"unverified",null,[],[79],"G03AA12",{"status":81,"forms":82,"refs":95},"registered",[83,87,91],{"code":84,"en":85,"fa":86},"17222","DROSPIRENONE\u002FETHINYL ESTRADIOL 2\u002F1MG TAB","قرص دروسپیرنون \u002F اتینیل استرادیول ۲ \u002F ۱ میلی‌گرم",{"code":88,"en":89,"fa":90},"14870","DROSPIRENONE\u002FETHINYL ESTRADIOL 3\u002F0.02MG TAB","قرص دروسپیرنون \u002F اتینیل استرادیول ۳ \u002F ۰٫۰۲ میلی‌گرم",{"code":92,"en":93,"fa":94},"09090","DROSPIRENONE\u002FETHINYL ESTRADIOL 3\u002F0.03MG TAB","قرص دروسپیرنون \u002F اتینیل استرادیول ۳ \u002F ۰٫۰۳ میلی‌گرم",[96],{"source":97,"section":98,"url":99},"darooyab-generic","G-4627\u002FDrospirenone-Ethinylestradiol","https:\u002F\u002Fwww.darooyab.ir\u002FG-4627\u002FDrospirenone-Ethinylestradiol",[101,105,109,113,116,119],{"kind":102,"url":103,"label":104},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=021098","NDA021098",{"kind":106,"url":107,"label":108},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=d7ea6a60-5a56-4f81-b206-9b27b7e58875","FDA Yasmin",{"kind":110,"url":111,"label":112},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa625047.html","Ethinyl Estradiol and Drosperinone (Oral Contraceptive)",{"kind":110,"url":114,"label":115},"https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa601050.html","Ethinyl Estradiol and Norethindrone (Oral Contraceptives)",{"kind":117,"url":118,"label":79},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=G03AA12",{"kind":120,"url":99,"label":121},"darooyab","Drospirenone-Ethinylestradiol",{"pregnancy":123,"lactation":132,"pediatric":140,"geriatric":148},{"level":124,"text":125,"quote":128,"refs":129},"caution",{"fa":126,"en":127},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary There is no use for contraception in pregnancy; therefore, Yasmin should be discontinued during pregnancy.",[130],{"source":33,"section":131},"8.1",{"level":124,"text":133,"quote":136,"refs":137},{"fa":134,"en":135},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary DRSP is present in human milk.",[138],{"source":33,"section":139},"8.2",{"level":124,"text":141,"quote":144,"refs":145},{"fa":142,"en":143},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","Safety and efficacy of Yasmin has been established in women of reproductive age.",[146],{"source":33,"section":147},"8.4",{"level":124,"text":149,"quote":152,"refs":153},{"fa":150,"en":151},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Yasmin has not been studied in postmenopausal women and is not indicated in this population.",[154],{"source":33,"section":155},"8.5",{"kind":157,"refs":158,"id":104},"NDA",[159],{"source":33,"section":160},"SPL approval \u002F marketing category",1792091058135]