[{"data":1,"prerenderedAt":127},["ShallowReactive",2],{"drug-donepezil":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":21,"regimens":52,"contraindications":99,"warnings":109,"renal":110,"monitoring":111,"interactions":112,"review":113,"examples":116},"donepezil",1,{"fa":7,"en":8},"دونپزیل","Donepezil","neurology",{"fa":11,"en":12},"مهارکننده کولین‌استراز","Cholinesterase inhibitor",[14],{"name":15,"market":16},"Aricept","US",[18,19,7,20],"aricept","آریسپت","آلزایمر",[22,36,44],{"id":23,"form":24,"route":25,"label":26,"concentration":27,"markets":31,"refs":32},"tab-5","tablet","oral","5 mg tablet",{"amount":28,"unit":29,"perUnit":24,"scored":30},5,"mg",false,[16],[33],{"source":34,"section":35},"fda-donepezil","3",{"id":37,"form":24,"route":25,"label":38,"concentration":39,"markets":41,"refs":42},"tab-10","10 mg tablet",{"amount":40,"unit":29,"perUnit":24,"scored":30},10,[16],[43],{"source":34,"section":35},{"id":45,"form":24,"route":25,"label":46,"concentration":47,"markets":49,"refs":50},"tab-23","23 mg tablet",{"amount":48,"unit":29,"perUnit":24,"scored":30},23,[16],[51],{"source":34,"section":35},[53,75],{"id":54,"disease":55,"label":56,"population":59,"type":63,"unit":29,"dose":64,"refs":65,"notes":68},"mild","alzheimers",{"fa":57,"en":58},"آلزایمر خفیف تا متوسط — ۵ mg شب","Mild–moderate Alzheimer’s — 5 mg in the evening",{"minAge":60},{"value":61,"unit":62},18,"year","fixed",{"perDose":28,"dosesPerDay":5},[66],{"source":34,"section":67},"2.1",[69],{"text":70,"refs":73},{"fa":71,"en":72},"۱۰ mg فقط پس از ۴ تا ۶ هفته مصرف ۵ mg.","10 mg only after 4–6 weeks on 5 mg.",[74],{"source":34,"section":67},{"id":76,"disease":55,"label":77,"population":80,"type":63,"unit":29,"dose":82,"refs":83,"limits":86,"notes":90},"severe",{"fa":78,"en":79},"آلزایمر متوسط تا شدید — ۱۰ mg (تا ۲۳ mg)","Moderate–severe Alzheimer’s — 10 mg (up to 23 mg)",{"minAge":81},{"value":61,"unit":62},{"perDose":40,"dosesPerDay":5},[84],{"source":34,"section":85},"2.2",{"maxPerDay":48,"refs":87},[88],{"source":34,"section":89},"2",[91],{"text":92,"refs":95},{"fa":93,"en":94},"۲۳ mg فقط پس از حداقل ۳ ماه مصرف ۱۰ mg؛ قرص ۲۳ mg شکسته یا جویده نشود.","23 mg only after at least 3 months on 10 mg; do not split or chew the 23 mg tablet.",[96,97],{"source":34,"section":85},{"source":34,"section":98},"2.3",[100],{"id":101,"severity":102,"text":103,"refs":106},"ci","block",{"fa":104,"en":105},"حساسیت به دونپزیل یا مشتقات پیپریدین.","Hypersensitivity to donepezil or piperidine derivatives.",[107],{"source":34,"section":108},"4",[],[],[],[],{"status":114,"reviewer":115,"date":115},"unverified",null,[117,122],{"regimen":54,"formulation":23,"input":118,"expect":121},{"ageYears":119,"weightKg":120},75,65,{"perDose":28},{"regimen":76,"formulation":37,"input":123,"expect":126},{"ageYears":124,"weightKg":125},80,60,{"perDose":40},1792078534656]