[{"data":1,"prerenderedAt":114},["ShallowReactive",2],{"drug-diclofenac":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":20,"regimens":35,"contraindications":79,"warnings":89,"renal":97,"monitoring":98,"interactions":99,"review":100,"examples":103},"diclofenac",1,{"fa":7,"en":8},"دیکلوفناک","Diclofenac sodium","analgesics",{"fa":11,"en":12},"ضدالتهاب غیراستروئیدی (NSAID)","NSAID",[14],{"name":15,"market":16},"Voltaren","US",[18,19,7,4],"ولتارن","voltaren",[21],{"id":22,"form":23,"route":24,"label":25,"concentration":26,"markets":30,"refs":31},"dr-75","tablet","oral","75 mg delayed-release tablet",{"amount":27,"unit":28,"perUnit":23,"scored":29},75,"mg",false,[16],[32],{"source":33,"section":34},"fda-diclofenac-dr","How Supplied",[36,52,63],{"id":37,"disease":38,"label":39,"population":42,"type":46,"unit":28,"dose":47,"refs":49},"oa","osteoarthritis",{"fa":40,"en":41},"آرتروز — ۷۵ mg دو بار در روز (۱۰۰ تا ۱۵۰ mg\u002Fday)","Osteoarthritis — 75 mg twice daily (100–150 mg\u002Fday)",{"minAge":43},{"value":44,"unit":45},18,"year","fixed",{"perDose":27,"dosesPerDay":48},2,[50],{"source":33,"section":51},"Dosage and Administration",{"id":53,"disease":54,"label":55,"population":58,"type":46,"unit":28,"dose":60,"refs":61},"ra","rheumatoid-arthritis",{"fa":56,"en":57},"آرتریت روماتوئید — ۷۵ mg دو بار در روز (۱۵۰ تا ۲۰۰ mg\u002Fday)","Rheumatoid arthritis — 75 mg twice daily (150–200 mg\u002Fday)",{"minAge":59},{"value":44,"unit":45},{"perDose":27,"dosesPerDay":48},[62],{"source":33,"section":51},{"id":64,"disease":65,"label":66,"population":69,"type":71,"unit":28,"dose":72,"refs":76},"child","pain",{"fa":67,"en":68},"کودکان","Children",{"maxAge":70},{"value":44,"unit":45},"notCalculated",{"reason":73},{"fa":74,"en":75},"بی‌خطری و اثربخشی در کودکان ثابت نشده است.","Safety and effectiveness in pediatric patients have not been established.",[77],{"source":33,"section":78},"Pediatric Use",[80],{"id":81,"severity":82,"text":83,"refs":86},"nsaid","block",{"fa":84,"en":85},"حساسیت به دیکلوفناک؛ سابقه آسم، کهیر یا واکنش آلرژیک پس از آسپرین\u002FNSAID؛ جراحی CABG.","Hypersensitivity to diclofenac; asthma, urticaria or allergic reactions after aspirin\u002FNSAIDs; CABG surgery.",[87],{"source":33,"section":88},"Contraindications",[90],{"text":91,"refs":94},{"fa":92,"en":93},"هشدار جعبه‌ای: افزایش خطر حوادث قلبی‌عروقی ترومبوتیک (سکته قلبی و مغزی) و خونریزی\u002Fزخم\u002Fسوراخ شدن گوارش.","Boxed warning: increased risk of serious cardiovascular thrombotic events (MI, stroke) and GI bleeding, ulceration and perforation.",[95],{"source":33,"section":96},"WARNING: RISK OF SERIOUS CARDIOVASCULAR AND GASTROINTESTINAL EVENTS",[],[],[],{"status":101,"reviewer":102,"date":102},"unverified",null,[104,109],{"regimen":37,"formulation":22,"input":105,"expect":107},{"ageYears":106,"weightKg":27},60,{"tabletsPerDoseRounded":5,"perDay":108},150,{"regimen":53,"formulation":22,"input":110,"expect":113},{"ageYears":111,"weightKg":112},50,70,{"perDose":27},1792078534318]