[{"data":1,"prerenderedAt":135},["ShallowReactive",2],{"drug-clopidogrel":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":21,"regimens":44,"contraindications":105,"warnings":115,"renal":116,"monitoring":117,"interactions":118,"review":119,"examples":122},"clopidogrel",1,{"fa":7,"en":8},"کلوپیدوگرل","Clopidogrel","cardiovascular",{"fa":11,"en":12},"مهارکننده P2Y12 (ضدپلاکت)","P2Y12 inhibitor (antiplatelet)",[14],{"name":15,"market":16},"Plavix","US",[18,19,7,20],"plavix","پلاویکس","ضد پلاکت",[22,36],{"id":23,"form":24,"route":25,"label":26,"concentration":27,"markets":31,"refs":32},"tab-75","tablet","oral","75 mg tablet",{"amount":28,"unit":29,"perUnit":24,"scored":30},75,"mg",false,[16],[33],{"source":34,"section":35},"fda-clopidogrel","3",{"id":37,"form":24,"route":25,"label":38,"concentration":39,"markets":41,"refs":42},"tab-300","300 mg tablet",{"amount":40,"unit":29,"perUnit":24,"scored":30},300,[16],[43],{"source":34,"section":35},[45,68,78,90],{"id":46,"disease":47,"label":48,"population":51,"type":55,"unit":29,"dose":56,"refs":57,"durationDays":60,"notes":61},"acs-load","acute-coronary-syndrome",{"fa":49,"en":50},"سندرم حاد کرونری — دوز بارگیری ۳۰۰ mg (یک‌بار)","ACS — loading dose 300 mg (once)",{"minAge":52},{"value":53,"unit":54},18,"year","fixed",{"perDose":40,"dosesPerDay":5},[58],{"source":34,"section":59},"2.1",{"min":5,"max":5},[62],{"text":63,"refs":66},{"fa":64,"en":65},"سپس ۷۵ mg یک بار در روز. بدون دوز بارگیری، اثر ضدپلاکتی چند روز دیرتر می‌رسد.","Then 75 mg once daily. Without a loading dose the antiplatelet effect is delayed by several days.",[67],{"source":34,"section":59},{"id":69,"disease":47,"label":70,"population":73,"type":55,"unit":29,"dose":75,"refs":76},"maint",{"fa":71,"en":72},"سندرم حاد کرونری — نگهدارنده ۷۵ mg یک بار در روز","ACS — maintenance 75 mg once daily",{"minAge":74},{"value":53,"unit":54},{"perDose":28,"dosesPerDay":5},[77],{"source":34,"section":59},{"id":79,"disease":80,"label":81,"population":84,"type":55,"unit":29,"dose":86,"refs":87},"prevent","atherothrombotic-prevention",{"fa":82,"en":83},"MI یا سکته مغزی اخیر، PAD — ۷۵ mg یک بار در روز","Recent MI or stroke, PAD — 75 mg once daily",{"minAge":85},{"value":53,"unit":54},{"perDose":28,"dosesPerDay":5},[88],{"source":34,"section":89},"2.2",{"id":91,"disease":80,"label":92,"population":95,"type":97,"unit":29,"dose":98,"refs":102},"peds",{"fa":93,"en":94},"زیر ۱۸ سال","Under 18 years",{"maxAge":96},{"value":53,"unit":54},"notCalculated",{"reason":99},{"fa":100,"en":101},"بی‌خطری و اثربخشی در کودکان ثابت نشده است.","Safety and effectiveness in pediatric patients not established.",[103],{"source":34,"section":104},"8.4",[106],{"id":107,"severity":108,"text":109,"refs":112},"ci","block",{"fa":110,"en":111},"خونریزی پاتولوژیک فعال (زخم پپتیک، خونریزی داخل جمجمه)؛ حساسیت.","Active pathological bleeding (peptic ulcer, intracranial haemorrhage); hypersensitivity.",[113],{"source":34,"section":114},"4",[],[],[],[],{"status":120,"reviewer":121,"date":121},"unverified",null,[123,128,132],{"regimen":46,"formulation":37,"input":124,"expect":127},{"ageYears":125,"weightKg":126},60,80,{"perDose":40},{"regimen":79,"formulation":23,"input":129,"expect":131},{"ageYears":130,"weightKg":130},70,{"perDose":28},{"regimen":69,"formulation":23,"input":133,"expect":134},{"ageYears":125,"weightKg":126},{"perDay":28},1792078533685]