[{"data":1,"prerenderedAt":256},["ShallowReactive",2],{"drug-chlorpromazine":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":20,"formulations":24,"regimens":63,"contraindications":139,"warnings":150,"renal":158,"monitoring":159,"interactions":160,"review":161,"examples":164,"atc":178,"iran":180,"links":208,"populations":225,"usApproval":251},"chlorpromazine",1,{"fa":7,"en":8},"کلرپرومازین","Chlorpromazine","nervous-system",{"fa":11,"en":12},"ضدروان‌پریشی تیپیک","Typical antipsychotic (phenothiazine)",[14,17],{"name":15,"market":16},"Thorazine","US",{"name":18,"market":19},"Largactil","GB",[21,22,23,7],"largactil","thorazine","لارگاکتیل",[25,39,47,55],{"id":26,"form":27,"route":28,"label":29,"concentration":30,"markets":34,"refs":35},"tab-10","tablet","oral","10 mg tablet",{"amount":31,"unit":32,"perUnit":27,"scored":33},10,"mg",false,[16],[36],{"source":37,"section":38},"fda-chlorpromazine","How Supplied",{"id":40,"form":27,"route":28,"label":41,"concentration":42,"markets":44,"refs":45},"tab-25","25 mg tablet",{"amount":43,"unit":32,"perUnit":27,"scored":33},25,[16],[46],{"source":37,"section":38},{"id":48,"form":27,"route":28,"label":49,"concentration":50,"markets":52,"refs":53},"tab-50","50 mg tablet",{"amount":51,"unit":32,"perUnit":27,"scored":33},50,[16],[54],{"source":37,"section":38},{"id":56,"form":27,"route":28,"label":57,"concentration":58,"markets":60,"refs":61},"tab-100","100 mg tablet",{"amount":59,"unit":32,"perUnit":27,"scored":33},100,[16],[62],{"source":37,"section":38},[64,80,99,115],{"id":65,"disease":66,"label":67,"population":70,"type":74,"unit":32,"dose":75,"refs":77},"nv","nausea-vomiting",{"fa":68,"en":69},"تهوع و استفراغ — ۱۰ تا ۲۵ mg هر ۴ تا ۶ ساعت","Nausea and vomiting — 10–25 mg every 4–6 h",{"minAge":71},{"value":72,"unit":73},18,"year","fixed",{"perDose":31,"perDoseMax":43,"dosesPerDay":76},4,[78],{"source":37,"section":79},"Dosage and Administration — Adults",{"id":81,"disease":82,"label":83,"population":86,"type":74,"unit":32,"dose":88,"refs":90,"notes":92},"hiccup","hiccups",{"fa":84,"en":85},"سکسکه مقاوم — ۲۵ تا ۵۰ mg سه تا چهار بار در روز","Intractable hiccups — 25–50 mg three to four times daily",{"minAge":87},{"value":72,"unit":73},{"perDose":43,"perDoseMax":51,"dosesPerDay":89},3,[91],{"source":37,"section":79},[93],{"text":94,"refs":97},{"fa":95,"en":96},"اگر ۲ تا ۳ روز ادامه یافت، تزریقی.","If persisting 2–3 days, parenteral therapy.",[98],{"source":37,"section":79},{"id":100,"disease":101,"label":102,"population":105,"type":107,"unit":32,"dose":108,"refs":112},"psych","schizophrenia",{"fa":103,"en":104},"روان‌پریشی — دوز فردی (معمولاً تا ۲۰۰ mg در روز)","Psychosis — individualised (200 mg\u002Fday not unusual)",{"minAge":106},{"value":72,"unit":73},"notCalculated",{"reason":109},{"fa":110,"en":111},"برچسب: دوز بر اساس شدت؛ ۲۰۰ mg در روز غیرمعمول نیست و بعضی بیماران دوز بالاتر لازم دارند. قرص ۱۰۰ و ۲۰۰ mg فقط برای موارد شدید.","Label: dose by severity; 200 mg\u002Fday is not unusual and some need more. 100\u002F200 mg tablets only for severe conditions.",[113],{"source":37,"section":114},"Dosage and Administration",{"id":116,"disease":66,"label":117,"population":120,"type":126,"unit":32,"dose":127,"refs":129,"notes":132},"nv-child",{"fa":118,"en":119},"تهوع و استفراغ — کودک ۶ ماه تا ۱۲ سال: ۰٫۲۵ mg به ازای هر پوند (حدود ۰٫۵۵ mg\u002Fkg) هر ۴ تا ۶ ساعت","Nausea and vomiting — child 6 months–12 y: ¼ mg\u002Flb (about 0.55 mg\u002Fkg) every 4–6 h",{"minAge":121,"maxAge":124},{"value":122,"unit":123},6,"month",{"value":125,"unit":73},13,"weightBased",{"perKgPerDose":128,"intervalHours":122},0.55,[130],{"source":37,"section":131},"Dosage and Administration — Pediatric Patients",[133],{"text":134,"refs":137},{"fa":135,"en":136},"¼ mg\u002Flb به ۰٫۵۵ mg\u002Fkg تبدیل شده؛ مثال برچسب: کودک ۴۰ پوندی (۱۸ kg) ← ۱۰ mg.","¼ mg\u002Flb converted to 0.55 mg\u002Fkg; label example: 40-lb (18 kg) child → 10 mg.",[138],{"source":37,"section":131},[140],{"id":141,"severity":142,"rule":143,"text":145,"refs":148},"child","block",{"maxAge":144},{"value":122,"unit":123},{"fa":146,"en":147},"زیر ۶ ماه مگر در شرایط نجات‌بخش.","Under 6 months except where potentially lifesaving.",[149],{"source":37,"section":131},[151],{"text":152,"refs":155},{"fa":153,"en":154},"هشدار جعبه‌ای: افزایش مرگ در سالمندان مبتلا به دمانس با روان‌پریشی.","Boxed warning: increased mortality in elderly patients with dementia-related psychosis.",[156],{"source":37,"section":157},"Boxed Warning",[],[],[],{"status":162,"reviewer":163,"date":163},"unverified",null,[165,170,173],{"regimen":65,"formulation":26,"input":166,"expect":169},{"ageYears":167,"weightKg":168},40,70,{"perDose":31,"tabletsPerDoseRounded":5},{"regimen":81,"formulation":40,"input":171,"expect":172},{"ageYears":167,"weightKg":168},{"perDose":43,"upperPerDose":51},{"regimen":116,"formulation":26,"input":174,"expect":176},{"ageYears":175,"weightKg":72},5,{"perDose":177,"tabletsPerDoseRounded":5},9.9,[179],"N05AA01",{"status":181,"forms":182,"refs":203},"registered",[183,187,191,195,199],{"code":184,"en":185,"fa":186},"52674","CHLORPROMAZINE SOLUTION ORAL 25 mg\u002F5mL 125 ML","محلول خوراکی کلرپرومازین ۲۵ میلی‌گرم \u002F ۵ میلی‌لیتر ۱۲۵ میلی‌لیتر",{"code":188,"en":189,"fa":190},"00278","CHLORPROMAZINE HCL 100MG TAB","قرص کلرپرومازین هیدروکلراید ۱۰۰ میلی‌گرم",{"code":192,"en":193,"fa":194},"01432","CHLORPROMAZINE HCL 200MG TAB","قرص کلرپرومازین هیدروکلراید ۲۰۰ میلی‌گرم",{"code":196,"en":197,"fa":198},"00279","CHLORPROMAZINE HCL 25MG TAB","قرص کلرپرومازین هیدروکلراید ۲۵ میلی‌گرم",{"code":200,"en":201,"fa":202},"00277","CHLORPROMAZINE HCL 50MG\u002F2ML AMP","آمپول کلرپرومازین هیدروکلراید ۵۰ میلی‌گرم \u002F ۲ میلی‌لیتر",[204],{"source":205,"section":206,"url":207},"darooyab-generic","G-1249\u002FChlorpromazine","https:\u002F\u002Fwww.darooyab.ir\u002FG-1249\u002FChlorpromazine",[209,213,217,220,223],{"kind":210,"url":211,"label":212},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=213368","ANDA213368",{"kind":214,"url":215,"label":216},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=2bd42d3a-bf89-4d74-a252-9b914106a570","FDA Chlorpromazine",{"kind":218,"url":219,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa682040.html",{"kind":221,"url":222,"label":179},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=N05AA01",{"kind":224,"url":207,"label":8},"darooyab",{"pregnancy":226,"lactation":235,"geriatric":244},{"level":227,"text":228,"quote":231,"refs":232},"caution",{"fa":229,"en":230},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Chlorpromazine hydrochloride should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.",[233],{"source":37,"section":234},"Precautions\u002FWarnings – Usage in Pregnancy",{"level":236,"text":237,"quote":240,"refs":241},"avoid",{"fa":238,"en":239},"برچسب: شیردهی توصیه نمی‌شود یا باید بین دارو و شیردهی یکی انتخاب شود.","Label: breastfeeding not recommended, or choose between the drug and breastfeeding.","Because of the potential for serious adverse reactions in nursing infants from chlorpromazine, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.",[242],{"source":37,"section":243},"Precautions\u002FWarnings – Nursing Mothers",{"level":236,"text":245,"quote":248,"refs":249},{"fa":246,"en":247},"برچسب: در سالمندان هشدار جدی یا پرهیز.","Label: serious warning or avoid in older adults.","Increased Mortality in Elderly Patients with Dementia-Related Psychosis Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death.",[250],{"source":37,"section":157},{"kind":252,"refs":253,"id":212},"ANDA",[254],{"source":37,"section":255},"SPL approval \u002F marketing category",1792092027636]