[{"data":1,"prerenderedAt":222},["ShallowReactive",2],{"drug-cariprazine":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":21,"regimens":60,"contraindications":120,"warnings":130,"renal":138,"monitoring":139,"interactions":140,"review":141,"examples":144,"atc":160,"iran":162,"usApproval":169,"links":175,"populations":189},"cariprazine",1,{"fa":7,"en":8},"کاریپرازین","Cariprazine","nervous-system",{"fa":11,"en":12},"آنتی‌سایکوتیک آتیپیک","Atypical antipsychotic",[14],{"name":15,"market":16},"Vraylar","US",[18,19,20,7],"vraylar","reagila","ورایلار",[22,36,44,52],{"id":23,"form":24,"route":25,"label":26,"concentration":27,"markets":31,"refs":32},"cap-1-5","capsule","oral","1.5 mg capsule",{"amount":28,"unit":29,"perUnit":24,"scored":30},1.5,"mg",false,[16],[33],{"source":34,"section":35},"fda-vraylar","3",{"id":37,"form":24,"route":25,"label":38,"concentration":39,"markets":41,"refs":42},"cap-3","3 mg capsule",{"amount":40,"unit":29,"perUnit":24,"scored":30},3,[16],[43],{"source":34,"section":35},{"id":45,"form":24,"route":25,"label":46,"concentration":47,"markets":49,"refs":50},"cap-4-5","4.5 mg capsule",{"amount":48,"unit":29,"perUnit":24,"scored":30},4.5,[16],[51],{"source":34,"section":35},{"id":53,"form":24,"route":25,"label":54,"concentration":55,"markets":57,"refs":58},"cap-6","6 mg capsule",{"amount":56,"unit":29,"perUnit":24,"scored":30},6,[16],[59],{"source":34,"section":35},[61,85,97,109],{"id":62,"disease":63,"label":64,"population":67,"type":71,"unit":29,"dose":72,"refs":73,"notes":76},"scz","schizophrenia",{"fa":65,"en":66},"اسکیزوفرنی بزرگسال — شروع ۱٫۵ mg، محدوده ۱٫۵ تا ۶ mg یک بار در روز","Adult schizophrenia — start 1.5 mg, range 1.5–6 mg once daily",{"minAge":68},{"value":69,"unit":70},18,"year","fixed",{"perDose":28,"perDoseMax":56,"dosesPerDay":5},[74],{"source":34,"section":75},"2.2",[77],{"text":78,"refs":81},{"fa":79,"en":80},"روز ۲ می‌تواند ۳ mg شود. به دلیل نیمه‌عمر طولانی، اثر تغییر دوز تا چند هفته دیده می‌شود.","May increase to 3 mg on day 2. 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Dangerous in pregnancy.","Based on animal data, VRAYLAR may cause fetal harm.",[197],{"source":34,"section":198},"8.1",{"level":200,"text":201,"quote":204,"refs":205},"caution",{"fa":202,"en":203},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary Lactation studies have not been conducted to assess the presence of cariprazine in human milk, the effects on the breastfed infant, or the effects on milk production.",[206],{"source":34,"section":207},"8.2",{"level":191,"text":209,"quote":212,"refs":213},{"fa":210,"en":211},"هشدار جعبه‌ای برچسب درباره کودکان.","Boxed warning in the label about children.","Suicidal Thoughts and Behaviors Antidepressants increased the risk of suicidal thoughts and behaviors in pediatric and young adult patients in short-term studies.",[214],{"source":34,"section":137},{"level":191,"text":216,"quote":219,"refs":220},{"fa":217,"en":218},"برچسب: در سالمندان هشدار جدی یا پرهیز.","Label: serious warning or avoid in older adults.","Increased Mortality in Elderly Patients with Dementia-Related Psychosis Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death.",[221],{"source":34,"section":137},1792156167383]