[{"data":1,"prerenderedAt":249},["ShallowReactive",2],{"drug-budesonide-formoterol":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":21,"regimens":35,"contraindications":83,"warnings":93,"renal":101,"monitoring":102,"interactions":103,"review":104,"examples":107,"atc":122,"iran":124,"links":188,"populations":210,"usApproval":244},"budesonide-formoterol",1,{"fa":7,"en":8},"بودزوناید + فورموترول (سیمبیکورت)","Budesonide + formoterol","respiratory",{"fa":11,"en":12},"کورتون استنشاقی + بتاآگونیست طولانی‌اثر","ICS + LABA",[14],{"name":15,"market":16},"Symbicort","US",[18,19,20],"symbicort","سیمبیکورت","بودزوناید فورموترول",[22],{"id":23,"form":24,"route":25,"label":26,"concentration":27,"markets":30,"refs":31},"mdi-80","inhaler","inhaled","80 mcg budesonide \u002F 4.5 mcg formoterol per actuation",{"amount":5,"unit":28,"perUnit":29},"spray","actuation",[16],[32],{"source":33,"section":34},"fda-symbicort","3",[36,54,63],{"id":37,"disease":38,"label":39,"population":42,"type":48,"unit":28,"dose":49,"refs":51},"asthma-child","asthma",{"fa":40,"en":41},"آسم ۶ تا زیر ۱۲ سال — ۲ پاف ۸۰\u002F۴٫۵ دو بار در روز","Asthma 6 to \u003C12 y — 2 puffs 80\u002F4.5 twice daily",{"minAge":43,"maxAge":46},{"value":44,"unit":45},6,"year",{"value":47,"unit":45},12,"fixed",{"perDose":50,"dosesPerDay":50},2,[52],{"source":33,"section":53},"2.2",{"id":38,"disease":38,"label":55,"population":58,"type":48,"unit":28,"dose":60,"refs":61},{"fa":56,"en":57},"آسم ۱۲ سال به بالا — ۲ پاف (۸۰\u002F۴٫۵ یا ۱۶۰\u002F۴٫۵) دو بار در روز","Asthma ≥12 y — 2 puffs (80\u002F4.5 or 160\u002F4.5) twice daily",{"minAge":59},{"value":47,"unit":45},{"perDose":50,"dosesPerDay":50},[62],{"source":33,"section":53},{"id":64,"disease":64,"label":65,"population":68,"type":48,"unit":28,"dose":71,"refs":72,"notes":75},"copd",{"fa":66,"en":67},"COPD — ۲ پاف ۱۶۰\u002F۴٫۵ دو بار در روز","COPD — 2 puffs 160\u002F4.5 twice daily",{"minAge":69},{"value":70,"unit":45},18,{"perDose":50,"dosesPerDay":50},[73],{"source":33,"section":74},"2.3",[76],{"text":77,"refs":80},{"fa":78,"en":79},"این فرآورده ۸۰\u002F۴٫۵ است؛ برای COPD قدرت ۱۶۰\u002F۴٫۵.","This product is 80\u002F4.5; COPD uses 160\u002F4.5.",[81,82],{"source":33,"section":74},{"source":33,"section":34},[84],{"id":85,"severity":86,"text":87,"refs":90},"acute","block",{"fa":88,"en":89},"درمان اولیه حمله حاد آسم یا COPD (استاتوس آسماتیکوس).","Primary treatment of status asthmaticus or acute asthma\u002FCOPD episodes.",[91],{"source":33,"section":92},"4",[94],{"text":95,"refs":98},{"fa":96,"en":97},"پس از هر بار مصرف دهان را بشویید (برفک دهان).","Rinse mouth after each use (oral thrush).",[99],{"source":33,"section":100},"5",[],[],[],{"status":105,"reviewer":106,"date":106},"unverified",null,[108,113,118],{"regimen":37,"formulation":23,"input":109,"expect":112},{"ageYears":110,"weightKg":111},8,25,{"perDose":50},{"regimen":38,"formulation":23,"input":114,"expect":117},{"ageYears":115,"weightKg":116},30,70,{"perDose":50},{"regimen":64,"formulation":23,"input":119,"expect":121},{"ageYears":120,"weightKg":116},60,{"perDose":50},[123],"R03AK07",{"status":125,"forms":126,"refs":183},"registered",[127,131,135,139,143,147,151,155,159,163,167,171,175,179],{"code":128,"en":129,"fa":130},"21368","BUDESONIDE\u002FFORMOTEROL 160\u002F4.5MCG 120DOSE INHALER","فرآورده استنشاقی بودزوناید \u002F فورموترول ۱۶۰ \u002F ۴٫۵ میکروگرم ۱۲۰ دوز",{"code":132,"en":133,"fa":134},"16506","BUDESONIDE\u002FFORMOTEROL 160\u002F4.5MCG 60DOSE INHALER","فرآورده استنشاقی بودزوناید \u002F فورموترول ۱۶۰ \u002F ۴٫۵ میکروگرم ۶۰ دوز",{"code":136,"en":137,"fa":138},"13695","BUDESONIDE\u002FFORMOTEROL 200\u002F12MCG SPRAY","اسپری بودزوناید \u002F فورموترول ۲۰۰ \u002F ۱۲ میکروگرم",{"code":140,"en":141,"fa":142},"16503","BUDESONIDE\u002FFORMOTEROL 320\u002F9MCG INHALER","فرآورده استنشاقی بودزوناید \u002F فورموترول ۳۲۰ \u002F ۹ میکروگرم",{"code":144,"en":145,"fa":146},"21486","BUDESONIDE\u002FFORMOTEROL 400\u002F12MCG INHALER","فرآورده استنشاقی بودزوناید \u002F فورموترول ۴۰۰ \u002F ۱۲ میکروگرم",{"code":148,"en":149,"fa":150},"13696","BUDESONIDE\u002FFORMOTEROL 400\u002F24MCG SPRAY","اسپری بودزوناید \u002F فورموترول ۴۰۰ \u002F ۲۴ میکروگرم",{"code":152,"en":153,"fa":154},"16502","BUDESONIDE\u002FFORMOTEROL 80\u002F4.5MCG INHALER","فرآورده استنشاقی بودزوناید \u002F فورموترول ۸۰ \u002F ۴٫۵ میکروگرم",{"code":156,"en":157,"fa":158},"52440","BUDESONIDE \u002F FORMOTEROL FUMARATE AEROSOL, METERED RESPIRATORY 160 ug\u002F4.5 ug\u002F1{dose} 120 {Puff}","فرآورده استنشاقی بودزوناید \u002F فورموترول فومارات ۱۶۰ میکروگرم \u002F ۴٫۵ میکروگرم \u002F ۱ { دوز } ۱۲۰ { }",{"code":160,"en":161,"fa":162},"52441","BUDESONIDE \u002F FORMOTEROL FUMARATE AEROSOL, METERED RESPIRATORY 80 ug\u002F4.5 ug\u002F1{dose} 120 {Puff}","فرآورده استنشاقی بودزوناید \u002F فورموترول فومارات ۸۰ میکروگرم \u002F ۴٫۵ میکروگرم \u002F ۱ { دوز } ۱۲۰ { }",{"code":164,"en":165,"fa":166},"50929","BUDESONIDE \u002F FORMOTEROL FUMARATE POWDER, METERED RESPIRATORY 320 ug\u002F9 ug\u002F1{dose} 120 {dose}","پودر بودزوناید \u002F فورموترول فومارات ۳۲۰ میکروگرم \u002F ۹ میکروگرم \u002F ۱ { دوز } ۱۲۰ { دوز }",{"code":168,"en":169,"fa":170},"52151","BUDESONIDE \u002F FORMOTEROL FUMARATE POWDER, METERED RESPIRATORY 80 ug\u002F4.5 ug\u002F1{dose} 60 {dose}","پودر بودزوناید \u002F فورموترول فومارات ۸۰ میکروگرم \u002F ۴٫۵ میکروگرم \u002F ۱ { دوز } ۶۰ { دوز }",{"code":172,"en":173,"fa":174},"52854","BUDESONIDE \u002F FORMOTEROL FUMARATE CAPSULE RESPIRATORY 320 ug\u002F9 ug","کپسول بودزوناید \u002F فورموترول فومارات ۳۲۰ میکروگرم \u002F ۹ میکروگرم",{"code":176,"en":177,"fa":178},"52853","BUDESONIDE \u002F FORMOTEROL FUMARATE CAPSULE RESPIRATORY 160 ug\u002F4.5 ug","کپسول بودزوناید \u002F فورموترول فومارات ۱۶۰ میکروگرم \u002F ۴٫۵ میکروگرم",{"code":180,"en":181,"fa":182},"52861","BUDESONIDE \u002F FORMOTEROL FUMARATE CAPSULE RESPIRATORY 160 ug\u002F9 ug","کپسول بودزوناید \u002F فورموترول فومارات ۱۶۰ میکروگرم \u002F ۹ میکروگرم",[184],{"source":185,"section":186,"url":187},"darooyab-generic","G-4623\u002FBudesonide-Formoterol","https:\u002F\u002Fwww.darooyab.ir\u002FG-4623\u002FBudesonide-Formoterol",[189,193,197,201,204,207],{"kind":190,"url":191,"label":192},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=021929","NDA021929",{"kind":194,"url":195,"label":196},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=a645756c-c692-4bc6-a858-7e7e249561bd","FDA Symbicort",{"kind":198,"url":199,"label":200},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa623022.html","Budesonide and Formoterol Oral Inhalation",{"kind":198,"url":202,"label":203},"https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa699056.html","Budesonide Oral Inhalation",{"kind":205,"url":206,"label":123},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=R03AK07",{"kind":208,"url":187,"label":209},"darooyab","Budesonide-Formoterol",{"pregnancy":211,"lactation":220,"pediatric":228,"geriatric":236},{"level":212,"text":213,"quote":216,"refs":217},"caution",{"fa":214,"en":215},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary There are no adequate and well-controlled studies of SYMBICORT or one of its individual components, formoterol fumarate, in pregnant women; however studies are available for the other component budesonide.",[218],{"source":33,"section":219},"8.1",{"level":212,"text":221,"quote":224,"refs":225},{"fa":222,"en":223},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary There are no available data on the effects of SYMBICORT, budesonide or formoterol fumarate on the breastfed child or on milk production.",[226],{"source":33,"section":227},"8.2",{"level":212,"text":229,"quote":232,"refs":233},{"fa":230,"en":231},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","Safety and effectiveness of SYMBICORT in asthma patients 12 years of age and older have been established in studies up to 12 months.",[234],{"source":33,"section":235},"8.4",{"level":212,"text":237,"quote":240,"refs":241},{"fa":238,"en":239},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","As with other products containing beta 2 -agonists, special caution should be observed when using SYMBICORT in geriatric patients who have concomitant cardiovascular disease that could be adversely affected by beta 2 -agonists.",[242],{"source":33,"section":243},"8.5",{"kind":245,"refs":246,"id":192},"NDA",[247],{"source":33,"section":248},"SPL approval \u002F marketing category",1792092025140]