[{"data":1,"prerenderedAt":147},["ShallowReactive",2],{"drug-aclidinium":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":20,"regimens":35,"contraindications":51,"warnings":61,"renal":69,"monitoring":70,"interactions":71,"review":72,"examples":75,"atc":81,"iran":83,"usApproval":90,"links":96,"populations":111},"aclidinium",1,{"fa":7,"en":8},"آکلیدینیوم","Aclidinium","respiratory",{"fa":11,"en":12},"آنتی‌موسکارینی طولانی‌اثر (LAMA)","Long-acting muscarinic antagonist (LAMA)",[14],{"name":15,"market":16},"Tudorza Pressair","US",[18,19,7],"tudorza","eklira",[21],{"id":22,"form":23,"route":24,"label":25,"concentration":26,"markets":30,"refs":31},"pressair","inhaler","inhaled","400 mcg per actuation (Pressair)",{"amount":27,"unit":28,"perUnit":29},400,"mcg","actuation",[16],[32],{"source":33,"section":34},"fda-tudorza","3",[36],{"id":37,"disease":37,"label":38,"population":41,"type":45,"unit":28,"dose":46,"refs":48},"copd",{"fa":39,"en":40},"نگهدارنده COPD — یک استنشاق ۴۰۰ mcg دو بار در روز (صبح و شب)","COPD maintenance — 1 inhalation of 400 mcg twice daily (morning and evening)",{"minAge":42},{"value":43,"unit":44},18,"year","fixed",{"perDose":27,"dosesPerDay":47},2,[49],{"source":33,"section":50},"2",[52],{"id":53,"severity":54,"text":55,"refs":58},"ci","block",{"fa":56,"en":57},"حساسیت شدید به پروتئین شیر؛ حساسیت به آکلیدینیوم.","Severe hypersensitivity to milk proteins; hypersensitivity to aclidinium.",[59],{"source":33,"section":60},"4",[62],{"text":63,"refs":66},{"fa":64,"en":65},"برای حمله حاد نیست؛ برونکواسپاسم متناقض؛ تشدید گلوکوم زاویه بسته و احتباس ادرار؛ حساسیت.","Not for acute episodes; paradoxical bronchospasm; worsening narrow-angle glaucoma and urinary retention; hypersensitivity.",[67],{"source":33,"section":68},"5",[],[],[],{"status":73,"reviewer":74,"date":74},"unverified",null,[76],{"regimen":37,"formulation":22,"input":77,"expect":80},{"ageYears":78,"weightKg":79},65,70,{"perDose":27,"tabletsPerDoseRounded":5},[82],"R03BB05",{"status":84,"refs":85},"not-found",[86],{"source":87,"section":88,"url":89},"darooyab-generic","search","https:\u002F\u002Fwww.darooyab.ir\u002FSearch?q=Aclidinium",{"kind":91,"refs":92,"id":95},"NDA",[93],{"source":33,"section":94},"SPL approval \u002F marketing category","NDA202450",[97,100,104,108],{"kind":98,"url":99,"label":95},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=202450",{"kind":101,"url":102,"label":103},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=6f92cceb-a63f-4470-99b6-56179d98f10f","FDA Tudorza Pressair",{"kind":105,"url":106,"label":107},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa613001.html","Aclidinium Oral Inhalation",{"kind":109,"url":110,"label":82},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=R03BB05",{"pregnancy":112,"lactation":121,"pediatric":129,"geriatric":138},{"level":113,"text":114,"quote":117,"refs":118},"caution",{"fa":115,"en":116},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary There are no adequate and well controlled studies of TUDORZA PRESSAIR in pregnant women to inform drug associated risks.",[119],{"source":33,"section":120},"8.1",{"level":113,"text":122,"quote":125,"refs":126},{"fa":123,"en":124},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary There are no available data on the effects of TUDORZA PRESSAIR or aclidinium bromide on the breastfed child or on milk production or presence in human milk.",[127],{"source":33,"section":128},"8.2",{"level":130,"text":131,"quote":134,"refs":135},"not-established",{"fa":132,"en":133},"برچسب: ایمنی و اثربخشی در کودکان ثابت نشده است.","Label: safety and effectiveness in children have not been established.","The safety and effectiveness of TUDORZA PRESSAIR in pediatric patients have not been established.",[136],{"source":33,"section":137},"8.4",{"level":139,"text":140,"quote":143,"refs":144},"ok",{"fa":141,"en":142},"برچسب: در سالمندان تفاوت یا تنظیم دوز خاصی ذکر نشده.","Label: no specific difference or dose adjustment stated for older adults.","No overall differences in safety or effectiveness were observed between these subjects and younger subjects.",[145],{"source":33,"section":146},"8.5",1792191523670]