[{"data":1,"prerenderedAt":154},["ShallowReactive",2],{"drug-acamprosate":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":20,"regimens":35,"contraindications":60,"warnings":70,"renal":71,"monitoring":72,"interactions":73,"review":74,"examples":77,"atc":84,"iran":86,"usApproval":98,"links":104,"populations":120},"acamprosate",1,{"fa":7,"en":8},"آکامپروسات","Acamprosate","nervous-system",{"fa":11,"en":12},"داروی حفظ پرهیز از الکل","Alcohol abstinence maintenance",[14],{"name":15,"market":16},"Campral","US",[18,19,7],"campral","کمپرال",[21],{"id":22,"form":23,"route":24,"label":25,"concentration":26,"markets":30,"refs":31},"tab-333","tablet","oral","333 mg delayed-release tablet",{"amount":27,"unit":28,"perUnit":23,"scored":29},333,"mg",false,[16],[32],{"source":33,"section":34},"fda-acamprosate","3",[36],{"id":37,"disease":38,"label":39,"population":42,"type":46,"unit":28,"dose":47,"refs":50,"notes":53},"std","alcohol-use-disorder",{"fa":40,"en":41},"حفظ پرهیز از الکل — ۶۶۶ mg (۲ قرص) سه بار در روز","Maintaining alcohol abstinence — 666 mg (2 tablets) three times daily",{"minAge":43},{"value":44,"unit":45},18,"year","fixed",{"perDose":48,"dosesPerDay":49},666,3,[51],{"source":33,"section":52},"2",[54],{"text":55,"refs":58},{"fa":56,"en":57},"هرچه زودتر پس از دوره ترک و پس از رسیدن به پرهیز شروع؛ در صورت عود ادامه. ترجیحاً با وعده‌ها.","Start as soon as possible after withdrawal once abstinent; continue through relapse. Preferably with meals.",[59],{"source":33,"section":52},[61],{"id":62,"severity":63,"text":64,"refs":67},"ci","block",{"fa":65,"en":66},"حساسیت؛ نارسایی شدید کلیه.","Hypersensitivity; severe renal impairment.",[68],{"source":33,"section":69},"4",[],[],[],[],{"status":75,"reviewer":76,"date":76},"unverified",null,[78],{"regimen":37,"formulation":22,"input":79,"expect":82},{"ageYears":80,"weightKg":81},45,75,{"perDose":48,"tabletsPerDoseRounded":83},2,[85],"N07BB03",{"status":87,"forms":88,"refs":93},"registered",[89],{"code":90,"en":91,"fa":92},"09245","ACAMPROSATE CALCIUM 333MG TAB","قرص آکامپروسات کلسیم ۳۳۳ میلی‌گرم",[94],{"source":95,"section":96,"url":97},"darooyab-generic","G-1218\u002FAcamprosate","https:\u002F\u002Fwww.darooyab.ir\u002FG-1218\u002FAcamprosate",{"kind":99,"refs":100,"id":103},"ANDA",[101],{"source":33,"section":102},"SPL approval \u002F marketing category","ANDA218984",[105,108,112,115,118],{"kind":106,"url":107,"label":103},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=218984",{"kind":109,"url":110,"label":111},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=1cfe4675-766f-4f1a-b1a8-96bbdacfcfa5","FDA Acamprosate DR",{"kind":113,"url":114,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa604028.html",{"kind":116,"url":117,"label":85},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=N07BB03",{"kind":119,"url":97,"label":8},"darooyab",{"pregnancy":121,"lactation":130,"pediatric":138,"geriatric":146},{"level":122,"text":123,"quote":126,"refs":127},"caution",{"fa":124,"en":125},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Acamprosate calcium should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.",[128],{"source":33,"section":129},"8.1",{"level":122,"text":131,"quote":134,"refs":135},{"fa":132,"en":133},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Because many drugs are excreted in human milk, caution should be exercised when acamprosate calcium is administered to a nursing woman.",[136],{"source":33,"section":137},"8.3",{"level":122,"text":139,"quote":142,"refs":143},{"fa":140,"en":141},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","The safety and efficacy of acamprosate calcium have not been established in the pediatric population.",[144],{"source":33,"section":145},"8.4",{"level":122,"text":147,"quote":150,"refs":151},{"fa":148,"en":149},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function [ see Clinical Pharmacology ( 12.3 ), Adverse Reactions ( 6.1 ), and Dosage and Administration ( 2.1 ) ].",[152],{"source":33,"section":153},"8.5",1792115165638]