[{"data":1,"prerenderedAt":189},["ShallowReactive",2],{"drug-zaleplon":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":20,"regimens":43,"contraindications":80,"warnings":90,"renal":98,"monitoring":99,"interactions":100,"review":101,"examples":104,"atc":114,"iran":116,"usApproval":132,"links":138,"populations":154},"zaleplon",1,{"fa":7,"en":8},"زالپلون","Zaleplon","nervous-system",{"fa":11,"en":12},"خواب‌آور غیربنزودیازپینی (Z-drug)","Non-benzodiazepine hypnotic (Z-drug)",[14],{"name":15,"market":16},"Sonata","US",[18,19,7],"sonata","سوناتا",[21,35],{"id":22,"form":23,"route":24,"label":25,"concentration":26,"markets":30,"refs":31},"cap-10","capsule","oral","10 mg capsule",{"amount":27,"unit":28,"perUnit":23,"scored":29},10,"mg",false,[16],[32],{"source":33,"section":34},"fda-zaleplon","How Supplied",{"id":36,"form":23,"route":24,"label":37,"concentration":38,"markets":40,"refs":41},"cap-5","5 mg capsule",{"amount":39,"unit":28,"perUnit":23,"scored":29},5,[16],[42],{"source":33,"section":34},[44,69],{"id":45,"disease":46,"label":47,"population":50,"type":56,"unit":28,"dose":57,"refs":59,"notes":62},"ins","insomnia",{"fa":48,"en":49},"بی‌خوابی (کوتاه‌مدت) بزرگسال — ۱۰ mg درست پیش از خواب","Insomnia (short-term), adults — 10 mg immediately before bedtime",{"minAge":51,"maxAge":54},{"value":52,"unit":53},18,"year",{"value":55,"unit":53},65,"fixed",{"perDose":27,"perDoseMax":58,"dosesPerDay":5},20,[60],{"source":33,"section":61},"Dosage and Administration",[63],{"text":64,"refs":67},{"fa":65,"en":66},"یا پس از رفتن به رختخواب و ناتوانی در خوابیدن. وزن کم: ۵ mg ممکن است کافی باشد. بیش از ۲۰ mg توصیه نمی‌شود.","Or after going to bed with difficulty falling asleep. Low weight: 5 mg may suffice. Not above 20 mg.",[68],{"source":33,"section":61},{"id":70,"disease":46,"label":71,"population":74,"type":56,"unit":28,"dose":76,"refs":77},"eld",{"fa":72,"en":73},"سالمند یا ناتوان — ۵ mg","Elderly or debilitated — 5 mg",{"minAge":75},{"value":55,"unit":53},{"perDose":39,"dosesPerDay":5},[78],{"source":33,"section":79},"Precautions",[81],{"id":82,"severity":83,"text":84,"refs":87},"ci","block",{"fa":85,"en":86},"سابقه رفتار پیچیده خواب با زالپلون؛ حساسیت.","Prior complex sleep behaviours with zaleplon; hypersensitivity.",[88],{"source":33,"section":89},"Contraindications",[91],{"text":92,"refs":95},{"fa":93,"en":94},"هشدار جعبه‌ای: رفتارهای پیچیده خواب (راه رفتن یا رانندگی در خواب) گاه با آسیب جدی یا مرگ — در صورت بروز فوراً قطع شود.","Boxed warning: complex sleep behaviours (sleep-walking, sleep-driving) sometimes causing serious injury or death — stop immediately if they occur.",[96],{"source":33,"section":97},"Boxed Warning",[],[],[],{"status":102,"reviewer":103,"date":103},"unverified",null,[105,110],{"regimen":45,"formulation":22,"input":106,"expect":109},{"ageYears":107,"weightKg":108},40,70,{"perDose":27,"tabletsPerDoseRounded":5,"upperPerDose":58},{"regimen":70,"formulation":36,"input":111,"expect":113},{"ageYears":112,"weightKg":55},72,{"perDose":39,"tabletsPerDoseRounded":5},[115],"N05CF03",{"status":117,"forms":118,"refs":127},"registered",[119,123],{"code":120,"en":121,"fa":122},"07129","ZALEPLON 10MG CAP","کپسول زالپلون ۱۰ میلی‌گرم",{"code":124,"en":125,"fa":126},"17947","ZALEPLON 5MG CAP","کپسول زالپلون ۵ میلی‌گرم",[128],{"source":129,"section":130,"url":131},"darooyab-generic","G-1368\u002FZaleplon","https:\u002F\u002Fwww.darooyab.ir\u002FG-1368\u002FZaleplon",{"kind":133,"refs":134,"id":137},"ANDA",[135],{"source":33,"section":136},"SPL approval \u002F marketing category","ANDA077237",[139,142,146,149,152],{"kind":140,"url":141,"label":137},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=077237",{"kind":143,"url":144,"label":145},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=cadd9d75-2139-4fab-94ce-2992e6a55780","FDA Zaleplon",{"kind":147,"url":148,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa601251.html",{"kind":150,"url":151,"label":115},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=N05CF03",{"kind":153,"url":131,"label":8},"darooyab",{"pregnancy":155,"lactation":164,"pediatric":172,"geriatric":181},{"level":156,"text":157,"quote":160,"refs":161},"caution",{"fa":158,"en":159},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","In embryofetal development studies in rats and rabbits, oral administration of up to 100 mg\u002Fkg\u002Fday and 50 mg\u002Fkg\u002Fday, respectively, to pregnant animals throughout organogenesis produced no evidence of teratogenicity.",[162],{"source":33,"section":163},"Pregnancy",{"level":156,"text":165,"quote":168,"refs":169},{"fa":166,"en":167},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","A study in lactating mothers indicated that the clearance and half-life of zaleplon is similar to that in young normal subjects.",[170],{"source":33,"section":171},"Nursing Mothers",{"level":173,"text":174,"quote":177,"refs":178},"not-established",{"fa":175,"en":176},"برچسب: ایمنی و اثربخشی در کودکان ثابت نشده است.","Label: safety and effectiveness in children have not been established.","The safety and effectiveness of zaleplon in pediatric patients have not been established.",[179],{"source":33,"section":180},"Pediatric Use",{"level":156,"text":182,"quote":185,"refs":186},{"fa":183,"en":184},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","In both sleep laboratory and outpatient studies, elderly patients with insomnia responded to a 5 mg dose with a reduced sleep latency, and thus 5 mg is the recommended dose in this population.",[187],{"source":33,"section":188},"Geriatric Use",1792191573514]