[{"data":1,"prerenderedAt":107},["ShallowReactive",2],{"drug-varenicline":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":20,"formulations":25,"regimens":47,"contraindications":73,"warnings":94,"renal":95,"monitoring":96,"interactions":97,"review":98,"examples":101},"varenicline",1,{"fa":7,"en":8},"وارنیکلین","Varenicline","psychiatry",{"fa":11,"en":12},"آگونیست نسبی نیکوتینی","Nicotinic partial agonist",[14,17],{"name":15,"market":16},"Chantix","US",{"name":18,"market":19},"Champix","GB",[21,22,23,7,24],"chantix","champix","شمپیکس","ترک سیگار",[26,40],{"id":27,"form":28,"route":29,"label":30,"concentration":31,"markets":35,"refs":36},"tab-0-5","tablet","oral","0.5 mg tablet",{"amount":32,"unit":33,"perUnit":28,"scored":34},0.5,"mg",false,[16],[37],{"source":38,"section":39},"fda-varenicline","3",{"id":41,"form":28,"route":29,"label":42,"concentration":43,"markets":44,"refs":45},"tab-1","1 mg tablet",{"amount":5,"unit":33,"perUnit":28,"scored":34},[16],[46],{"source":38,"section":39},[48],{"id":49,"disease":50,"label":51,"population":54,"type":58,"unit":33,"dose":59,"refs":61,"durationDays":64,"notes":66},"quit","smoking-cessation",{"fa":52,"en":53},"ترک سیگار — هفته اول تیتراسیون، سپس ۱ mg دو بار","Smoking cessation — week-1 titration, then 1 mg twice daily",{"minAge":55},{"value":56,"unit":57},18,"year","fixed",{"perDose":5,"dosesPerDay":60},2,[62],{"source":38,"section":63},"2",{"min":65,"max":65},84,[67],{"text":68,"refs":71},{"fa":69,"en":70},"روز ۱ تا ۳: ۰٫۵ mg یک بار؛ روز ۴ تا ۷: ۰٫۵ mg دو بار؛ سپس ۱ mg دو بار تا ۱۲ هفته. CrCl کمتر از ۳۰: حداکثر ۰٫۵ mg دو بار.","Days 1–3: 0.5 mg once daily; days 4–7: 0.5 mg twice daily; then 1 mg twice daily to 12 weeks. CrCl \u003C30: max 0.5 mg twice daily.",[72],{"source":38,"section":63},[74,83],{"id":75,"severity":76,"text":77,"refs":80},"ci","block",{"fa":78,"en":79},"سابقه حساسیت یا واکنش پوستی جدی به وارنیکلین.","History of serious hypersensitivity or skin reactions to varenicline.",[81],{"source":38,"section":82},"4",{"id":84,"severity":76,"rule":85,"text":88,"refs":91},"child",{"maxAge":86},{"value":87,"unit":57},17,{"fa":89,"en":90},"در ۱۶ سال و کمتر توصیه نمی‌شود.","Not recommended in patients 16 years or younger.",[92],{"source":38,"section":93},"8.4",[],[],[],[],{"status":99,"reviewer":100,"date":100},"unverified",null,[102],{"regimen":49,"formulation":41,"input":103,"expect":106},{"ageYears":104,"weightKg":105},40,80,{"perDose":5,"perDay":60},1792078541671]