[{"data":1,"prerenderedAt":192},["ShallowReactive",2],{"drug-valsartan":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":21,"regimens":61,"contraindications":138,"warnings":159,"renal":160,"monitoring":168,"interactions":169,"review":170,"examples":173},"valsartan",1,{"fa":7,"en":8},"والسارتان","Valsartan","cardiovascular",{"fa":11,"en":12},"مسدودکننده گیرنده آنژیوتانسین (ARB)","Angiotensin receptor blocker (ARB)",[14],{"name":15,"market":16},"Diovan","US",[18,19,7,20],"diovan","دیووان","ARB",[22,36,45,53],{"id":23,"form":24,"route":25,"label":26,"concentration":27,"markets":31,"refs":32},"tab-40","tablet","oral","40 mg tablet (scored)",{"amount":28,"unit":29,"perUnit":24,"scored":30},40,"mg",true,[16],[33],{"source":34,"section":35},"fda-valsartan","3",{"id":37,"form":24,"route":25,"label":38,"concentration":39,"markets":42,"refs":43},"tab-80","80 mg tablet",{"amount":40,"unit":29,"perUnit":24,"scored":41},80,false,[16],[44],{"source":34,"section":35},{"id":46,"form":24,"route":25,"label":47,"concentration":48,"markets":50,"refs":51},"tab-160","160 mg tablet",{"amount":49,"unit":29,"perUnit":24,"scored":41},160,[16],[52],{"source":34,"section":35},{"id":54,"form":24,"route":25,"label":55,"concentration":56,"markets":58,"refs":59},"tab-320","320 mg tablet",{"amount":57,"unit":29,"perUnit":24,"scored":41},320,[16],[60],{"source":34,"section":35},[62,88,114],{"id":63,"disease":64,"label":65,"population":68,"type":72,"unit":29,"dose":73,"refs":74,"limits":77,"notes":81},"adult-htn","hypertension",{"fa":66,"en":67},"فشار خون — بزرگسال: ۸۰ یا ۱۶۰ mg یک بار در روز","Hypertension — adults: 80 or 160 mg once daily",{"minAge":69},{"value":70,"unit":71},18,"year","fixed",{"perDose":40,"perDoseMax":49,"dosesPerDay":5},[75],{"source":34,"section":76},"2.2",{"maxPerDay":57,"refs":78},[79],{"source":34,"section":80},"2, Table",[82],{"text":83,"refs":86},{"fa":84,"en":85},"محدوده ۸۰ تا ۳۲۰ mg یک بار در روز.","Range 80–320 mg once daily.",[87],{"source":34,"section":76},{"id":89,"disease":64,"label":90,"population":93,"type":97,"unit":29,"dose":98,"refs":99,"limits":102,"notes":105},"peds-htn",{"fa":91,"en":92},"فشار خون — ۱ تا ۱۶ سال: ۱ mg\u002Fkg یک بار در روز (تا ۴۰ mg)","Hypertension — 1–16 y: 1 mg\u002Fkg once daily (up to 40 mg)",{"minAge":94,"maxAge":95},{"value":5,"unit":71},{"value":96,"unit":71},17,"weightBased",{"perKgPerDay":5,"dividedDoses":5},[100],{"source":34,"section":101},"2.3",{"maxPerDose":28,"refs":103},[104],{"source":34,"section":101},[106],{"text":107,"refs":110},{"fa":108,"en":109},"محدوده ۱ تا ۴ mg\u002Fkg یک بار (تا ۱۶۰ mg). برای ۱ تا ۵ سال یا وقتی دوز با قرص جور نیست، سوسپانسیون توصیه می‌شود.","Range 1–4 mg\u002Fkg once daily (up to 160 mg). Suspension recommended for ages 1–5 or when the dose does not match tablet strengths.",[111,112],{"source":34,"section":80},{"source":34,"section":113},"2.1",{"id":115,"disease":116,"label":117,"population":120,"type":72,"unit":29,"dose":122,"refs":124,"limits":127,"notes":130},"hf","heart-failure",{"fa":118,"en":119},"نارسایی قلبی — بزرگسال: شروع ۴۰ mg دو بار در روز","Heart failure — adults: start 40 mg twice daily",{"minAge":121},{"value":70,"unit":71},{"perDose":28,"dosesPerDay":123},2,[125],{"source":34,"section":126},"2.4",{"maxPerDay":57,"refs":128},[129],{"source":34,"section":126},[131],{"text":132,"refs":135},{"fa":133,"en":134},"محدوده ۴۰ تا ۱۶۰ mg دو بار؛ حداکثر ۳۲۰ mg\u002Fday در کارآزمایی‌ها.","Range 40–160 mg twice daily; max 320 mg\u002Fday in trials.",[136,137],{"source":34,"section":80},{"source":34,"section":126},[139,150],{"id":140,"severity":141,"rule":142,"text":144,"refs":147},"under-1","block",{"maxAge":143},{"value":5,"unit":71},{"fa":145,"en":146},"زیر ۱ سال توصیه نمی‌شود.","Not recommended under 1 year.",[148],{"source":34,"section":149},"8.4",{"id":151,"severity":152,"text":153,"refs":156},"pregnancy","warn",{"fa":154,"en":155},"هشدار جعبه‌ای: سمیت جنینی — با تشخیص بارداری فوراً قطع شود.","Boxed warning: fetal toxicity — stop as soon as pregnancy is detected.",[157],{"source":34,"section":158},"Boxed Warning",[],[161],{"egfrBelow":162,"severity":152,"text":163,"refs":166},30,{"fa":164,"en":165},"در کودکان با GFR کمتر از ۳۰ یا دیالیز داده‌ای نیست.","No data in children with GFR \u003C30 or on dialysis.",[167],{"source":34,"section":149},[],[],{"status":171,"reviewer":172,"date":172},"unverified",null,[174,178,182,187],{"regimen":63,"formulation":37,"input":175,"expect":177},{"ageYears":176,"weightKg":40},50,{"perDose":40,"upperPerDose":49},{"regimen":89,"formulation":23,"input":179,"expect":181},{"ageYears":180,"weightKg":28},12,{"perDose":28,"tabletsPerDoseRounded":5},{"regimen":89,"formulation":23,"input":183,"expect":186},{"ageYears":184,"weightKg":185},14,55,{"perDose":28},{"regimen":115,"formulation":23,"input":188,"expect":191},{"ageYears":189,"weightKg":190},65,70,{"perDay":40},1792078541641]