[{"data":1,"prerenderedAt":154},["ShallowReactive",2],{"drug-travoprost":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":20,"regimens":33,"contraindications":56,"warnings":57,"renal":71,"monitoring":72,"interactions":73,"review":74,"examples":77,"atc":83,"iran":85,"usApproval":97,"links":103,"populations":120},"travoprost",1,{"fa":7,"en":8},"تراووپروست","Travoprost","sensory-organs",{"fa":11,"en":12},"آنالوگ پروستاگلاندین (چشمی)","Prostaglandin analogue (ophthalmic)",[14],{"name":15,"market":16},"Travatan Z","US",[18,19,7],"travatan","تراواتان",[21],{"id":22,"form":23,"route":24,"label":25,"concentration":26,"markets":28,"refs":29},"drops","eye-drops","ophthalmic","0.004% (0.04 mg\u002FmL) eye drops",{"amount":5,"unit":27,"perUnit":27},"drop",[16],[30],{"source":31,"section":32},"fda-travatan-z","3",[34],{"id":35,"disease":36,"label":37,"population":40,"type":44,"unit":27,"dose":45,"refs":46,"notes":49},"glc","glaucoma",{"fa":38,"en":39},"گلوکوم زاویه باز یا فشار بالای چشم — یک قطره در چشم مبتلا یک بار شب","Open-angle glaucoma or ocular hypertension — 1 drop in the affected eye(s) once nightly",{"minAge":41},{"value":42,"unit":43},16,"year","fixed",{"perDose":5,"dosesPerDay":5},[47],{"source":31,"section":48},"2",[50],{"text":51,"refs":54},{"fa":52,"en":53},"بیش از یک بار در روز اثر را کم می‌کند.","More than once daily reduces the effect.",[55],{"source":31,"section":48},[],[58,65],{"text":59,"refs":62},{"fa":60,"en":61},"افزایش رنگدانه عنبیه (دائمی)، پلک و تغییر مژه؛ التهاب داخل چشم؛ ادم ماکولا.","Increased iris (permanent), eyelid pigmentation and eyelash changes; intraocular inflammation; macular oedema.",[63],{"source":31,"section":64},"5",{"text":66,"refs":69},{"fa":67,"en":68},"عفونت قرنیه با ظرف آلوده؛ لنز تماسی ۱۵ دقیقه پس از قطره.","Bacterial keratitis from contaminated containers; reinsert contact lenses 15 min after.",[70],{"source":31,"section":64},[],[],[],{"status":75,"reviewer":76,"date":76},"unverified",null,[78],{"regimen":35,"formulation":22,"input":79,"expect":82},{"ageYears":80,"weightKg":81},60,70,{"perDose":5},[84],"S01EE04",{"status":86,"forms":87,"refs":92},"registered",[88],{"code":89,"en":90,"fa":91},"09536","TRAVOPROST 0.04MG 2.5ML OPHTH DROP","قطره تراووپروست ۰٫۰۴ میلی‌گرم ۲٫۵ میلی‌لیتر افت",[93],{"source":94,"section":95,"url":96},"darooyab-generic","G-3194\u002FTravoprost","https:\u002F\u002Fwww.darooyab.ir\u002FG-3194\u002FTravoprost",{"kind":98,"refs":99,"id":102},"NDA",[100],{"source":31,"section":101},"SPL approval \u002F marketing category","NDA021994",[104,107,111,115,118],{"kind":105,"url":106,"label":102},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=021994",{"kind":108,"url":109,"label":110},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=028455e0-ae77-4213-8819-3b58ef7d6a14","FDA Travatan Z",{"kind":112,"url":113,"label":114},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa602027.html","Travoprost Ophthalmic",{"kind":116,"url":117,"label":84},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=S01EE04",{"kind":119,"url":96,"label":8},"darooyab",{"pregnancy":121,"lactation":130,"pediatric":138,"geriatric":146},{"level":122,"text":123,"quote":126,"refs":127},"caution",{"fa":124,"en":125},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary There are no adequate and well-controlled studies in pregnant women to inform a drug-associated risk.",[128],{"source":31,"section":129},"8.1",{"level":122,"text":131,"quote":134,"refs":135},{"fa":132,"en":133},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary There are no data on the effects of travoprost on the breastfed child or milk production.",[136],{"source":31,"section":137},"8.2",{"level":122,"text":139,"quote":142,"refs":143},{"fa":140,"en":141},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","Use in pediatric patients below the age of 16 years is not recommended because of potential safety concerns related to increased pigmentation following long-term chronic use.",[144],{"source":31,"section":145},"8.4",{"level":122,"text":147,"quote":150,"refs":151},{"fa":148,"en":149},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","No overall clinical differences in safety or effectiveness have been observed between elderly and other adult patients.",[152],{"source":31,"section":153},"8.5",1792191570281]