[{"data":1,"prerenderedAt":209},["ShallowReactive",2],{"drug-torsemide":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":21,"regimens":60,"contraindications":98,"warnings":108,"renal":109,"monitoring":110,"interactions":111,"review":112,"examples":115,"atc":126,"iran":128,"links":152,"populations":169,"usApproval":204},"torsemide",1,{"fa":7,"en":8},"تورسماید","Torsemide","cardiovascular",{"fa":11,"en":12},"دیورتیک لوپ","Loop diuretic",[14],{"name":15,"market":16},"Demadex","US",[18,19,7,20],"demadex","torasemide","تورازماید",[22,36,44,52],{"id":23,"form":24,"route":25,"label":26,"concentration":27,"markets":31,"refs":32},"tab-5","tablet","oral","5 mg tablet (scored)",{"amount":28,"unit":29,"perUnit":24,"scored":30},5,"mg",true,[16],[33],{"source":34,"section":35},"fda-torsemide","3",{"id":37,"form":24,"route":25,"label":38,"concentration":39,"markets":41,"refs":42},"tab-10","10 mg tablet (scored)",{"amount":40,"unit":29,"perUnit":24,"scored":30},10,[16],[43],{"source":34,"section":35},{"id":45,"form":24,"route":25,"label":46,"concentration":47,"markets":49,"refs":50},"tab-20","20 mg tablet (scored)",{"amount":48,"unit":29,"perUnit":24,"scored":30},20,[16],[51],{"source":34,"section":35},{"id":53,"form":24,"route":25,"label":54,"concentration":55,"markets":57,"refs":58},"tab-100","100 mg tablet (scored)",{"amount":56,"unit":29,"perUnit":24,"scored":30},100,[16],[59],{"source":34,"section":35},[61,83],{"id":62,"disease":63,"label":64,"population":67,"type":71,"unit":29,"dose":72,"refs":73,"notes":76},"hf","edema",{"fa":65,"en":66},"ادم نارسایی قلب — شروع ۱۰ یا ۲۰ mg یک بار در روز","Heart-failure oedema — start 10 or 20 mg once daily",{"minAge":68},{"value":69,"unit":70},18,"year","fixed",{"perDose":40,"perDoseMax":48,"dosesPerDay":5},[74],{"source":34,"section":75},"2.1",[77],{"text":78,"refs":81},{"fa":79,"en":80},"در صورت پاسخ ناکافی تقریباً دو برابر شود؛ بالای ۲۰۰ mg بررسی نشده. نارسایی مزمن کلیه: شروع ۲۰ mg؛ سیروز: ۵ یا ۱۰ mg (بالای ۴۰ mg بررسی نشده).","If inadequate, roughly double; >200 mg not studied. CKD: start 20 mg; cirrhosis: 5 or 10 mg (>40 mg not studied).",[82],{"source":34,"section":75},{"id":84,"disease":85,"label":86,"population":89,"type":71,"unit":29,"dose":91,"refs":92,"limits":95},"htn","hypertension",{"fa":87,"en":88},"فشار خون — ۵ mg یک بار در روز، در صورت نیاز ۱۰ mg","Hypertension — 5 mg once daily, 10 mg if needed",{"minAge":90},{"value":69,"unit":70},{"perDose":28,"dosesPerDay":5},[93],{"source":34,"section":94},"2.2",{"maxPerDose":40,"refs":96},[97],{"source":34,"section":94},[99],{"id":100,"severity":101,"text":102,"refs":105},"ci","block",{"fa":103,"en":104},"حساسیت به تورسماید؛ آنوری؛ کمای کبدی.","Hypersensitivity to torsemide; anuria; hepatic coma.",[106],{"source":34,"section":107},"4",[],[],[],[],{"status":113,"reviewer":114,"date":114},"unverified",null,[116,121],{"regimen":62,"formulation":37,"input":117,"expect":120},{"ageYears":118,"weightKg":119},65,75,{"perDose":40,"upperPerDose":48},{"regimen":84,"formulation":23,"input":122,"expect":125},{"ageYears":123,"weightKg":124},50,80,{"perDose":28,"tabletsPerDoseRounded":5},[127],"C03CA04",{"status":129,"forms":130,"refs":147},"registered",[131,135,139,143],{"code":132,"en":133,"fa":134},"53392","TORSEMIDE 100 mg TABLET","قرص تورسماید ۱۰۰ میلی‌گرم",{"code":136,"en":137,"fa":138},"53391","TORSEMIDE 20 mg TABLET","قرص تورسماید ۲۰ میلی‌گرم",{"code":140,"en":141,"fa":142},"53390","TORSEMIDE 10 mg TABLET","قرص تورسماید ۱۰ میلی‌گرم",{"code":144,"en":145,"fa":146},"53389","TORSEMIDE 5 mg TABLET","قرص تورسماید ۵ میلی‌گرم",[148],{"source":149,"section":150,"url":151},"darooyab-generic","G-1918\u002FTorsemide","https:\u002F\u002Fwww.darooyab.ir\u002FG-1918\u002FTorsemide",[153,157,161,164,167],{"kind":154,"url":155,"label":156},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=076346","ANDA076346",{"kind":158,"url":159,"label":160},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=7fc14338-92e4-cf57-a3e8-ef64d8d1026c","FDA Torsemide",{"kind":162,"url":163,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa601212.html",{"kind":165,"url":166,"label":127},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=C03CA04",{"kind":168,"url":151,"label":8},"darooyab",{"pregnancy":170,"lactation":179,"pediatric":187,"geriatric":196},{"level":171,"text":172,"quote":175,"refs":176},"caution",{"fa":173,"en":174},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary There are no available data on use of torsemide in pregnant women and the risk of major birth defects or miscarriage.",[177],{"source":34,"section":178},"8.1",{"level":171,"text":180,"quote":183,"refs":184},{"fa":181,"en":182},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary There are no data regarding the presence of torsemide in human milk or the effects of torsemide on the breastfed child.",[185],{"source":34,"section":186},"8.2",{"level":188,"text":189,"quote":192,"refs":193},"not-established",{"fa":190,"en":191},"برچسب: ایمنی و اثربخشی در کودکان ثابت نشده است.","Label: safety and effectiveness in children have not been established.","Safety and effectiveness in pediatric patients have not been established.",[194],{"source":34,"section":195},"8.4",{"level":171,"text":197,"quote":200,"refs":201},{"fa":198,"en":199},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Of the total number of patients who received torsemide in United States clinical studies, 24% were 65 or older while about 4% were 75 or older.",[202],{"source":34,"section":203},"8.5",{"kind":205,"refs":206,"id":156},"ANDA",[207],{"source":34,"section":208},"SPL approval \u002F marketing category",1792111470173]