[{"data":1,"prerenderedAt":165},["ShallowReactive",2],{"drug-timolol-eye":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":22,"regimens":42,"contraindications":64,"warnings":74,"renal":75,"monitoring":76,"interactions":77,"review":78,"examples":81,"atc":87,"iran":89,"links":109,"populations":124,"usApproval":160},"timolol-eye",1,{"fa":7,"en":8},"قطره تیمولول","Timolol eye drops","sensory-organs",{"fa":11,"en":12},"بتابلاکر چشمی","Ophthalmic beta-blocker",[14],{"name":15,"market":16},"Timoptic","US",[18,19,20,21],"timoptic","تیموپتیک","تیمولول","قطره فشار چشم",[23,35],{"id":24,"form":25,"route":26,"label":27,"concentration":28,"markets":30,"refs":31},"drops-0-25","eye-drops","ophthalmic","0.25% ophthalmic solution",{"amount":5,"unit":29,"perUnit":29},"drop",[16],[32],{"source":33,"section":34},"fda-timolol","How Supplied",{"id":36,"form":25,"route":26,"label":37,"concentration":38,"markets":39,"refs":40},"drops-0-5","0.5% ophthalmic solution",{"amount":5,"unit":29,"perUnit":29},[16],[41],{"source":33,"section":34},[43],{"id":44,"disease":44,"label":45,"population":48,"type":52,"unit":29,"dose":53,"refs":54,"notes":57},"glaucoma",{"fa":46,"en":47},"گلوکوم \u002F فشار بالای چشم — ۱ قطره ۰٫۲۵٪ دو بار در روز","Glaucoma \u002F ocular hypertension — 1 drop of 0.25% twice daily",{"minAge":49},{"value":50,"unit":51},2,"year","fixed",{"perDose":5,"dosesPerDay":50},[55],{"source":33,"section":56},"Dosage and Administration",[58],{"text":59,"refs":62},{"fa":60,"en":61},"اگر کافی نبود ۱ قطره ۰٫۵٪ دو بار در روز.","If not adequate, 1 drop of 0.5% twice daily.",[63],{"source":33,"section":56},[65],{"id":66,"severity":67,"text":68,"refs":71},"ci","block",{"fa":69,"en":70},"آسم یا سابقه آسم؛ COPD شدید؛ برادی‌کاردی سینوسی؛ بلوک درجه ۲ و ۳؛ نارسایی آشکار قلب؛ شوک کاردیوژنیک؛ حساسیت.","Asthma or history of asthma; severe COPD; sinus bradycardia; 2nd\u002F3rd-degree AV block; overt heart failure; cardiogenic shock; hypersensitivity.",[72],{"source":33,"section":73},"Contraindications",[],[],[],[],{"status":79,"reviewer":80,"date":80},"unverified",null,[82],{"regimen":44,"formulation":24,"input":83,"expect":86},{"ageYears":84,"weightKg":85},60,70,{"perDose":5},[88],"S01ED01",{"status":90,"forms":91,"refs":104},"registered",[92,96,100],{"code":93,"en":94,"fa":95},"01226","TIMOLOL MALEATE 0.5% 5ML OPH DROP","قطره چشمی تیمولول مالئات ۰٫۵ درصد ۵ میلی‌لیتر",{"code":97,"en":98,"fa":99},"01695","TIMOLOL MALEATE 10MG TAB","قرص تیمولول مالئات ۱۰ میلی‌گرم",{"code":101,"en":102,"fa":103},"01227","TIMOLOL MALEATE 5MG TAB","قرص تیمولول مالئات ۵ میلی‌گرم",[105],{"source":106,"section":107,"url":108},"darooyab-generic","G-1908\u002FTimolol","https:\u002F\u002Fwww.darooyab.ir\u002FG-1908\u002FTimolol",[110,114,118,121],{"kind":111,"url":112,"label":113},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=077259","ANDA077259",{"kind":115,"url":116,"label":117},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=2ed21930-1e05-46de-8acd-cb6f4798a7fa","FDA Timolol eye",{"kind":119,"url":120,"label":88},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=S01ED01",{"kind":122,"url":108,"label":123},"darooyab","Timolol",{"pregnancy":125,"lactation":134,"pediatric":143,"geriatric":151},{"level":126,"text":127,"quote":130,"refs":131},"caution",{"fa":128,"en":129},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Timolol maleate ophthalmic solution should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.",[132],{"source":33,"section":133},"Pregnancy:",{"level":135,"text":136,"quote":139,"refs":140},"avoid",{"fa":137,"en":138},"برچسب: شیردهی توصیه نمی‌شود یا باید بین دارو و شیردهی یکی انتخاب شود.","Label: breastfeeding not recommended, or choose between the drug and breastfeeding.","Because of the potential for serious adverse reactions from timolol maleate ophthalmic solution in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.",[141],{"source":33,"section":142},"Nursing Mothers",{"level":126,"text":144,"quote":147,"refs":148},{"fa":145,"en":146},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","Safety and effectiveness of timolol maleate ophthalmic solution have been established when administered in pediatric patients aged 2 years and older.",[149],{"source":33,"section":150},"Pediatric Use",{"level":152,"text":153,"quote":156,"refs":157},"ok",{"fa":154,"en":155},"برچسب: در سالمندان تفاوت یا تنظیم دوز خاصی ذکر نشده.","Label: no specific difference or dose adjustment stated for older adults.","No overall differences in safety or effectiveness have been observed between elderly and younger patients.",[158],{"source":33,"section":159},"Geriatric Use",{"kind":161,"refs":162,"id":113},"ANDA",[163],{"source":33,"section":164},"SPL approval \u002F marketing category",1792092045545]