[{"data":1,"prerenderedAt":163},["ShallowReactive",2],{"drug-tedizolid":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":20,"regimens":45,"contraindications":74,"warnings":75,"renal":83,"monitoring":84,"interactions":85,"review":86,"examples":89,"atc":95,"iran":97,"usApproval":104,"links":110,"populations":127},"tedizolid",1,{"fa":7,"en":8},"تدیزولید","Tedizolid","anti-infectives",{"fa":11,"en":12},"اکسازولیدینون","Oxazolidinone",[14],{"name":15,"market":16},"Sivextro","US",[18,19,7],"sivextro","سیوکسترو",[21,35],{"id":22,"form":23,"route":24,"label":25,"concentration":26,"markets":30,"refs":31},"tab-200","tablet","oral","200 mg tablet",{"amount":27,"unit":28,"perUnit":23,"scored":29},200,"mg",false,[16],[32],{"source":33,"section":34},"fda-sivextro","3",{"id":36,"form":37,"route":38,"label":39,"concentration":40,"markets":42,"refs":43},"vial-200","powder-for-injection","iv","200 mg vial",{"amount":27,"unit":28,"perUnit":41},"vial",[16],[44],{"source":33,"section":34},[46],{"id":47,"disease":48,"label":49,"population":52,"type":57,"unit":28,"dose":58,"refs":59,"durationDays":62,"notes":64},"absssi","skin-soft-tissue-infection",{"fa":50,"en":51},"عفونت حاد باکتریایی پوست — ۲۰۰ mg یک بار در روز، ۶ روز (خوراکی یا وریدی)","Acute bacterial skin infection — 200 mg once daily for 6 days (oral or IV)",{"minAge":53,"minWeightKg":56},{"value":54,"unit":55},12,"year",35,"fixed",{"perDose":27,"dosesPerDay":5},[60],{"source":33,"section":61},"2.2, Table 1",{"min":63,"max":63},6,[65],{"text":66,"refs":69},{"fa":67,"en":68},"قرص در کودک زیر ۳۵ kg داده نشود. تغییر وریدی به خوراکی بدون تنظیم دوز.","Do not give tablets to children under 35 kg. IV-to-oral switch needs no adjustment.",[70,72],{"source":33,"section":71},"2",{"source":33,"section":73},"2.2",[],[76],{"text":77,"refs":80},{"fa":78,"en":79},"در نوتروپنی اثر بررسی نشده؛ اسهال C. difficile.","Not evaluated in neutropenic patients; C. difficile diarrhoea.",[81],{"source":33,"section":82},"5",[],[],[],{"status":87,"reviewer":88,"date":88},"unverified",null,[90],{"regimen":47,"formulation":22,"input":91,"expect":94},{"ageYears":92,"weightKg":93},40,70,{"perDose":27,"tabletsPerDoseRounded":5},[96],"J01XX11",{"status":98,"refs":99},"not-found",[100],{"source":101,"section":102,"url":103},"darooyab-generic","search","https:\u002F\u002Fwww.darooyab.ir\u002FSearch?q=Tedizolid",{"kind":105,"refs":106,"id":109},"NDA",[107],{"source":33,"section":108},"SPL approval \u002F marketing category","NDA205435",[111,114,118,121,124],{"kind":112,"url":113,"label":109},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=205435",{"kind":115,"url":116,"label":117},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=75672079-589f-451a-bdbf-eaebcfcc80a9","FDA Sivextro",{"kind":119,"url":120,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa614038.html",{"kind":119,"url":122,"label":123},"https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa614039.html","Tedizolid Injection",{"kind":125,"url":126,"label":96},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=J01XX11",{"pregnancy":128,"lactation":137,"pediatric":146,"geriatric":154},{"level":129,"text":130,"quote":133,"refs":134},"avoid",{"fa":131,"en":132},"برچسب: می‌تواند به جنین آسیب بزند. در بارداری خطرناک است.","Label: can cause fetal harm. Dangerous in pregnancy.","Risk Summary Based on animal reproduction studies, SIVEXTRO may cause fetal harm when administered to pregnant women.",[135],{"source":33,"section":136},"8.1",{"level":138,"text":139,"quote":142,"refs":143},"caution",{"fa":140,"en":141},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary There is no information on the presence of tedizolid in human milk.",[144],{"source":33,"section":145},"8.2",{"level":138,"text":147,"quote":150,"refs":151},{"fa":148,"en":149},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","The safety and effectiveness of SIVEXTRO for the treatment of ABSSSI have been established in pediatric patients at least 26 weeks gestational age and weighing at least 1 kg.",[152],{"source":33,"section":153},"8.4",{"level":155,"text":156,"quote":159,"refs":160},"ok",{"fa":157,"en":158},"برچسب: در سالمندان تفاوت یا تنظیم دوز خاصی ذکر نشده.","Label: no specific difference or dose adjustment stated for older adults.","No overall differences in pharmacokinetics were observed between elderly subjects and younger subjects.",[161],{"source":33,"section":162},"8.5",1792191568225]