[{"data":1,"prerenderedAt":178},["ShallowReactive",2],{"drug-tazarotene":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":21,"regimens":33,"contraindications":68,"warnings":78,"renal":86,"monitoring":87,"interactions":88,"review":89,"examples":92,"atc":93,"iran":95,"links":111,"populations":130,"usApproval":173},"tazarotene",1,{"fa":7,"en":8},"تازاروتن (موضعی)","Tazarotene (topical)","dermatology",{"fa":11,"en":12},"رتینوئید موضعی","Topical retinoid",[14],{"name":15,"market":16},"Tazorac","US",[18,19,20],"tazorac","تازوراک","تازاروتن",[22],{"id":23,"form":23,"route":24,"label":25,"concentration":26,"markets":28,"refs":29},"cream","topical","Cream 0.05% and 0.1%",{"amount":5,"unit":27,"perUnit":27},"application",[16],[30],{"source":31,"section":32},"fda-tazorac-cream","3",[34,53],{"id":35,"disease":36,"label":37,"population":40,"type":44,"unit":45,"dose":46,"refs":50},"pso","psoriasis",{"fa":38,"en":39},"پسوریازیس پلاک — لایه نازک کرم ۰٫۰۵٪ (در صورت تحمل ۰٫۱٪) یک بار شب فقط روی ضایعات","Plaque psoriasis — thin film of 0.05% cream (0.1% if tolerated) once nightly on lesions only",{"minAge":41},{"value":42,"unit":43},18,"year","notCalculated","mg",{"reason":47},{"fa":48,"en":49},"دوز وزنی ندارد؛ حدود ۲ mg\u002Fcm² فقط روی ضایعه؛ پوست خشک باشد؛ نرم‌کننده یک ساعت قبل.","Not weight-dosed; about 2 mg\u002Fcm² on lesions only; skin dry; emollients an hour before.",[51],{"source":31,"section":52},"2.2",{"id":54,"disease":54,"label":55,"population":58,"type":44,"unit":45,"dose":61,"refs":65},"acne",{"fa":56,"en":57},"آکنه — لایه نازک کرم ۰٫۱٪ یک بار شب روی نواحی درگیر","Acne — thin layer of 0.1% cream once nightly to affected areas",{"minAge":59},{"value":60,"unit":43},12,{"reason":62},{"fa":63,"en":64},"پس از شستن ملایم و خشک شدن پوست؛ ضدآفتاب و پوشش محافظ.","After gentle cleansing and drying; use sunscreen and protective clothing.",[66],{"source":31,"section":67},"2.3",[69],{"id":70,"severity":71,"text":72,"refs":75},"ci","block",{"fa":73,"en":74},"بارداری؛ حساسیت به اجزا.","Pregnancy; hypersensitivity to any component.",[76],{"source":31,"section":77},"4",[79],{"text":80,"refs":83},{"fa":81,"en":82},"سمیت جنینی (تست بارداری منفی پیش از شروع و پیشگیری)؛ تحریک موضعی؛ حساسیت به نور و آفتاب‌سوختگی.","Embryofetal toxicity (negative pregnancy test and contraception); local irritation; photosensitivity and sunburn.",[84],{"source":31,"section":85},"5",[],[],[],{"status":90,"reviewer":91,"date":91},"unverified",null,[],[94],"D05AX05",{"status":96,"forms":97,"refs":106},"registered",[98,102],{"code":99,"en":100,"fa":101},"06734","TAZAROTENE 0.05% 30G GEL","ژل تازاروتن ۰٫۰۵ درصد ۳۰ گرم",{"code":103,"en":104,"fa":105},"06740","TAZAROTENE 0.1% 30G GEL","ژل تازاروتن ۰٫۱ درصد ۳۰ گرم",[107],{"source":108,"section":109,"url":110},"darooyab-generic","G-2333\u002FTazarotene-Topical","https:\u002F\u002Fwww.darooyab.ir\u002FG-2333\u002FTazarotene-Topical",[112,116,120,124,127],{"kind":113,"url":114,"label":115},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=021184","NDA021184",{"kind":117,"url":118,"label":119},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=021744d1-a6d7-4ad6-99c2-7187c24e64c6","FDA Tazorac cream",{"kind":121,"url":122,"label":123},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa616052.html","Tazarotene Topical",{"kind":125,"url":126,"label":94},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=D05AX05",{"kind":128,"url":110,"label":129},"darooyab","Tazarotene-Topical",{"pregnancy":131,"lactation":139,"pediatric":148,"geriatric":156,"reproductive":165},{"level":132,"text":133,"quote":136,"refs":137},"contraindicated",{"fa":134,"en":135},"برچسب: در بارداری منع مصرف دارد.","Label: contraindicated in pregnancy.","TAZORAC Cream is contraindicated in: Pregnancy.",[138],{"source":31,"section":77},{"level":140,"text":141,"quote":144,"refs":145},"caution",{"fa":142,"en":143},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary There is no information regarding the presence of tazarotene in human milk, the effects on the breastfed infant, or the effects on milk production.",[146],{"source":31,"section":147},"8.2",{"level":140,"text":149,"quote":152,"refs":153},{"fa":150,"en":151},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","The safety and efficacy of TAZORAC Cream have not been established in patients with psoriasis under the age of 18 years, or in patients with acne under the age of 12 years.",[154],{"source":31,"section":155},"8.4",{"level":157,"text":158,"quote":161,"refs":162},"ok",{"fa":159,"en":160},"برچسب: در سالمندان تفاوت یا تنظیم دوز خاصی ذکر نشده.","Label: no specific difference or dose adjustment stated for older adults.","No overall differences in safety or effectiveness were observed between these subjects and younger subjects.",[163],{"source":31,"section":164},"8.5",{"level":140,"text":166,"quote":169,"refs":170},{"fa":167,"en":168},"برچسب نکته‌ای درباره بارداری، پیشگیری یا باروری زنان و مردان دارد.","Label has advice on pregnancy testing, contraception or fertility for females and males.","Contraception Females Based on animal studies, TAZORAC Cream may cause fetal harm when administered to a pregnant woman [see Use in Specific Populations ( 8.1 )].",[171],{"source":31,"section":172},"8.3",{"kind":174,"refs":175,"id":115},"NDA",[176],{"source":31,"section":177},"SPL approval \u002F marketing category",1792191568147]