[{"data":1,"prerenderedAt":181},["ShallowReactive",2],{"drug-streptomycin":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":16,"formulations":17,"regimens":32,"contraindications":84,"warnings":94,"renal":104,"monitoring":105,"interactions":106,"review":107,"examples":110,"atc":121,"iran":123,"usApproval":135,"links":141,"populations":154},"streptomycin",1,{"fa":7,"en":8},"استرپتومایسین","Streptomycin","anti-infectives",{"fa":11,"en":12},"آمینوگلیکوزید","Aminoglycoside",[14],{"name":8,"market":15},"US",[4,7],[18],{"id":19,"form":20,"route":21,"label":22,"concentration":23,"markets":27,"refs":28},"vial-1g","powder-for-injection","im","1 g vial (IM after reconstitution)",{"amount":24,"unit":25,"perUnit":26},1000,"mg","vial",[15],[29],{"source":30,"section":31},"fda-streptomycin","How Supplied",[33,63],{"id":34,"disease":35,"label":36,"population":39,"type":43,"unit":25,"dose":44,"refs":47,"limits":50,"notes":54},"adult","brucellosis",{"fa":37,"en":38},"بروسلوز و سایر عفونت‌ها — بزرگسال: ۱ تا ۲ g در روز در دوزهای منقسم (عضلانی)","Brucellosis and other infections — adult: 1–2 g\u002Fday in divided doses (IM)",{"minAge":40},{"value":41,"unit":42},18,"year","fixed",{"perDose":45,"perDoseMax":24,"dosesPerDay":46},500,2,[48],{"source":30,"section":49},"Dosage and Administration — Other Infections",{"maxPerDay":51,"refs":52},2000,[53],{"source":30,"section":49},[55],{"text":56,"refs":59},{"fa":57,"en":58},"هر ۶ تا ۱۲ ساعت؛ معمولاً بیش از ۲ g در روز نشود. بالای ۶۰ سال و نارسایی کلیه دوز کمتر.","Every 6–12 h; generally not over 2 g\u002Fday. Reduce over 60 y and in renal impairment.",[60,61],{"source":30,"section":49},{"source":30,"section":62},"Dosage and Administration",{"id":64,"disease":35,"label":65,"population":68,"type":70,"unit":25,"dose":71,"refs":74,"notes":76},"child",{"fa":66,"en":67},"کودک — ۲۰ تا ۴۰ mg\u002Fkg\u002Fروز در دوزهای منقسم هر ۶ تا ۱۲ ساعت","Child — 20–40 mg\u002Fkg\u002Fday in divided doses every 6–12 h",{"maxAge":69},{"value":41,"unit":42},"weightBased",{"perKgPerDay":72,"perKgPerDayMax":73,"dividedDoses":46},20,40,[75],{"source":30,"section":49},[77],{"text":78,"refs":81},{"fa":79,"en":80},"از دوز بیش از حد در کودک به‌ویژه پرهیز شود (افسردگی CNS در شیرخوار).","Take particular care to avoid excessive doses in children (CNS depression in infants).",[82,83],{"source":30,"section":49},{"source":30,"section":62},[85],{"id":86,"severity":87,"text":88,"refs":91},"hyper","block",{"fa":89,"en":90},"سابقه حساسیت به استرپتومایسین یا سایر آمینوگلیکوزیدها.","History of hypersensitivity to streptomycin or other aminoglycosides.",[92],{"source":30,"section":93},"Contraindications",[95],{"text":96,"refs":99},{"fa":97,"en":98},"هشدار جعبه‌ای: خطر سمیت عصبی شدید (اختلال تعادل و شنوایی، عصب بینایی، نوریت محیطی، انسفالوپاتی) در نارسایی کلیه یا ازوتمی پیش‌کلیوی به‌شدت بیشتر است؛ عملکرد کلیه و شنوایی پایش شود.","Boxed warning: risk of severe neurotoxicity (vestibular and cochlear dysfunction, optic nerve dysfunction, peripheral neuritis, encephalopathy) is sharply increased with impaired renal function or prerenal azotaemia; monitor renal function and hearing.",[100,102],{"source":30,"section":101},"Boxed Warning",{"source":30,"section":103},"Warnings",[],[],[],{"status":108,"reviewer":109,"date":109},"unverified",null,[111,115],{"regimen":34,"formulation":19,"input":112,"expect":114},{"ageYears":73,"weightKg":113},70,{"perDose":45,"upperPerDose":24},{"regimen":64,"formulation":19,"input":116,"expect":118},{"ageYears":117,"weightKg":72},6,{"perDose":119,"upperPerDose":120},200,400,[122],"J01GA01",{"status":124,"forms":125,"refs":130},"registered",[126],{"code":127,"en":128,"fa":129},"01173","STREPTOMYCIN SULFATE 1 G VIAL","ویال سترپتومایسین سولفات ۱ گرم",[131],{"source":132,"section":133,"url":134},"darooyab-generic","G-506\u002FStreptomycin","https:\u002F\u002Fwww.darooyab.ir\u002FG-506\u002FStreptomycin",{"kind":136,"refs":137,"id":140},"ANDA",[138],{"source":30,"section":139},"SPL approval \u002F marketing category","ANDA064210",[142,145,149,152],{"kind":143,"url":144,"label":140},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=064210",{"kind":146,"url":147,"label":148},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=abd1f64e-4283-4370-aae8-3666316aa36e","FDA Streptomycin",{"kind":150,"url":151,"label":122},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=J01GA01",{"kind":153,"url":134,"label":8},"darooyab",{"pregnancy":155,"lactation":164,"pediatric":173},{"level":156,"text":157,"quote":160,"refs":161},"caution",{"fa":158,"en":159},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","See WARNINGS section.",[162],{"source":30,"section":163},"Pregnancy",{"level":165,"text":166,"quote":169,"refs":170},"avoid",{"fa":167,"en":168},"برچسب: شیردهی توصیه نمی‌شود یا باید بین دارو و شیردهی یکی انتخاب شود.","Label: breastfeeding not recommended, or choose between the drug and breastfeeding.","Because of the potential for serious adverse reactions in nursing infants from streptomycin, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.",[171],{"source":30,"section":172},"Nursing Mothers",{"level":156,"text":174,"quote":177,"refs":178},{"fa":175,"en":176},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","See DOSAGE AND ADMINISTRATION .",[179],{"source":30,"section":180},"Pediatric Use",1792115196158]