[{"data":1,"prerenderedAt":161},["ShallowReactive",2],{"drug-sodium-polystyrene-sulfonate":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":22,"regimens":37,"contraindications":63,"warnings":73,"renal":81,"monitoring":82,"interactions":83,"review":84,"examples":87,"atc":92,"iran":94,"links":110,"populations":129,"usApproval":156},"sodium-polystyrene-sulfonate",1,{"fa":7,"en":8},"سدیم پلی‌استایرن سولفونات (کی‌اگزالات)","Sodium polystyrene sulfonate","various",{"fa":11,"en":12},"رزین تبادل کاتیون","Cation-exchange resin",[14],{"name":15,"market":16},"Kayexalate","US",[18,19,20,21],"kayexalate","SPS","کی اگزالات","رزین پتاسیم",[23],{"id":24,"form":25,"route":26,"label":27,"concentration":28,"markets":32,"refs":33},"susp-15-60","suspension","oral","15 g \u002F 60 mL oral suspension",{"amount":29,"unit":30,"perVolumeMl":31},15,"g",60,[16],[34],{"source":35,"section":36},"fda-sps","How Supplied",[38],{"id":39,"disease":40,"label":41,"population":44,"type":48,"unit":30,"dose":49,"refs":50,"limits":53,"notes":56},"std","hyperkalemia",{"fa":42,"en":43},"هیپرکالمی — بزرگسال: ۱۵ g (۶۰ mL) یک تا چهار بار در روز","Hyperkalaemia — adult: 15 g (60 mL) one to four times daily",{"minAge":45},{"value":46,"unit":47},18,"year","fixed",{"perDose":29,"dosesPerDay":5},[51],{"source":35,"section":52},"Dosage and Administration",{"maxPerDay":31,"refs":54},[55],{"source":35,"section":52},[57],{"text":58,"refs":61},{"fa":59,"en":60},"میانگین روزانه ۱۵ تا ۶۰ g. دست‌کم ۳ ساعت فاصله با سایر داروهای خوراکی (گاستروپارزی ۶ ساعت). بیمار نشسته. هر ۶۰ mL حاوی ۱۵۰۰ mg سدیم. کودک: دوز کمتر بر پایه ۱ mEq پتاسیم به ازای هر گرم رزین.","Average 15–60 g\u002Fday. Separate from other oral drugs by ≥3 h (6 h with gastroparesis). Upright position. Each 60 mL contains 1,500 mg sodium. Children: lower doses based on 1 mEq K per g resin.",[62],{"source":35,"section":52},[64],{"id":65,"severity":66,"text":67,"refs":70},"ci","block",{"fa":68,"en":69},"هیپوکالمی؛ حساسیت به رزین؛ بیماری انسدادی روده؛ مصرف خوراکی یا رکتال در نوزاد.","Hypokalaemia; resin hypersensitivity; obstructive bowel disease; oral or rectal use in neonates.",[71],{"source":35,"section":72},"Contraindications",[74],{"text":75,"refs":78},{"fa":76,"en":77},"نکروز روده (گاهی کشنده) و عوارض جدی گوارشی؛ با سوربیتول مصرف نشود.","Intestinal necrosis (sometimes fatal) and serious GI events; avoid with sorbitol.",[79],{"source":35,"section":80},"Warnings",[],[],[],{"status":85,"reviewer":86,"date":86},"unverified",null,[88],{"regimen":39,"formulation":24,"input":89,"expect":91},{"ageYears":31,"weightKg":90},70,{"perDose":29,"mlPerDose":31},[93],"V03AE01",{"status":95,"forms":96,"refs":105},"registered",[97,101],{"code":98,"en":99,"fa":100},"05242","SODIUM POLYSTYRENE SULFONATE 15G SACHET","ساشه سدیم پولیستیرن سولفونات ۱۵ گرم",{"code":102,"en":103,"fa":104},"01156","SODIUM POLYSTYRENE SULFONATE 454 G POW FOR SUSP","پودر برای تهیه سوسپانسیون خوراکی سدیم پولیستیرن سولفونات ۴۵۴ گرم",[106],{"source":107,"section":108,"url":109},"darooyab-generic","G-1983\u002FSodium-Polystyrene-Sulfonate","https:\u002F\u002Fwww.darooyab.ir\u002FG-1983\u002FSodium-Polystyrene-Sulfonate",[111,115,119,123,126],{"kind":112,"url":113,"label":114},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=214912","ANDA214912",{"kind":116,"url":117,"label":118},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=8bbeae67-a7ff-4fa6-b21e-fb8617cd9197","FDA SPS suspension",{"kind":120,"url":121,"label":122},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa682108.html","Sodium Polystyrene Sulfonate",{"kind":124,"url":125,"label":93},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=V03AE01",{"kind":127,"url":109,"label":128},"darooyab","Sodium-Polystyrene-Sulfonate",{"pregnancy":130,"lactation":139,"pediatric":147},{"level":131,"text":132,"quote":135,"refs":136},"caution",{"fa":133,"en":134},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Animal reproduction studies have not been conducted with sodium polystyrene sulfonate.",[137],{"source":35,"section":138},"Pregnancy",{"level":131,"text":140,"quote":143,"refs":144},{"fa":141,"en":142},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Because many drugs are excreted in human milk, caution should be exercised when sodium polystyrene sulfonate is administered to a nursing woman.",[145],{"source":35,"section":146},"Nursing Mothers",{"level":148,"text":149,"quote":152,"refs":153},"not-established",{"fa":150,"en":151},"برچسب: ایمنی و اثربخشی در کودکان ثابت نشده است.","Label: safety and effectiveness in children have not been established.","The effectiveness of Sodium Polystyrene Sulfonate Suspension, USP in pediatric patients has not been established.",[154],{"source":35,"section":155},"Pediatric Use",{"kind":157,"refs":158,"id":114},"ANDA",[159],{"source":35,"section":160},"SPL approval \u002F marketing category",1792111468388]