[{"data":1,"prerenderedAt":143},["ShallowReactive",2],{"drug-rivaroxaban":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":21,"regimens":60,"contraindications":106,"warnings":125,"renal":126,"monitoring":127,"interactions":128,"review":129,"examples":132},"rivaroxaban",1,{"fa":7,"en":8},"ریواروکسابان","Rivaroxaban","cardiovascular",{"fa":11,"en":12},"ضدانعقاد خوراکی (مهارکننده فاکتور Xa)","Oral anticoagulant (factor Xa inhibitor)",[14],{"name":15,"market":16},"Xarelto","US",[18,19,7,20],"xarelto","زارلتو","DOAC",[22,36,44,52],{"id":23,"form":24,"route":25,"label":26,"concentration":27,"markets":31,"refs":32},"tab-2-5","tablet","oral","2.5 mg tablet",{"amount":28,"unit":29,"perUnit":24,"scored":30},2.5,"mg",false,[16],[33],{"source":34,"section":35},"fda-xarelto","3",{"id":37,"form":24,"route":25,"label":38,"concentration":39,"markets":41,"refs":42},"tab-10","10 mg tablet",{"amount":40,"unit":29,"perUnit":24,"scored":30},10,[16],[43],{"source":34,"section":35},{"id":45,"form":24,"route":25,"label":46,"concentration":47,"markets":49,"refs":50},"tab-15","15 mg tablet",{"amount":48,"unit":29,"perUnit":24,"scored":30},15,[16],[51],{"source":34,"section":35},{"id":53,"form":24,"route":25,"label":54,"concentration":55,"markets":57,"refs":58},"tab-20","20 mg tablet",{"amount":56,"unit":29,"perUnit":24,"scored":30},20,[16],[59],{"source":34,"section":35},[61,85],{"id":62,"disease":63,"label":64,"population":67,"type":71,"unit":29,"dose":72,"refs":73,"notes":76},"af","atrial-fibrillation",{"fa":65,"en":66},"AF غیردریچه‌ای — ۲۰ mg یک بار با شام","Non-valvular AF — 20 mg once daily with the evening meal",{"minAge":68},{"value":69,"unit":70},18,"year","fixed",{"perDose":56,"dosesPerDay":5},[74],{"source":34,"section":75},"2.1",[77],{"text":78,"refs":81},{"fa":79,"en":80},"بر اساس کلیرانس کراتینین ۱۵ یا ۲۰ mg. قرص‌های ۱۵ و ۲۰ mg با غذا.","15 or 20 mg depending on creatinine clearance. 15 and 20 mg tablets with food.",[82,84],{"source":34,"section":83},"2",{"source":34,"section":75},{"id":86,"disease":87,"label":88,"population":91,"type":71,"unit":29,"dose":93,"refs":95,"durationDays":97,"notes":99},"vte","venous-thromboembolism",{"fa":89,"en":90},"درمان DVT\u002FPE — ۱۵ mg دو بار با غذا ۲۱ روز، سپس ۲۰ mg یک بار","DVT\u002FPE — 15 mg twice daily with food for 21 days, then 20 mg once daily",{"minAge":92},{"value":69,"unit":70},{"perDose":48,"dosesPerDay":94},2,[96],{"source":34,"section":83},{"min":98,"max":98},21,[100],{"text":101,"refs":104},{"fa":102,"en":103},"پس از ۲۱ روز ۲۰ mg یک بار با غذا. پیشگیری از عود پس از ۶ ماه: ۱۰ mg یک بار.","After 21 days 20 mg once daily with food. Recurrence prevention after 6 months: 10 mg once daily.",[105],{"source":34,"section":83},[107,116],{"id":108,"severity":109,"text":110,"refs":113},"ci","block",{"fa":111,"en":112},"خونریزی پاتولوژیک فعال؛ حساسیت شدید.","Active pathological bleeding; severe hypersensitivity.",[114],{"source":34,"section":115},"4",{"id":117,"severity":118,"text":119,"refs":122},"boxed","warn",{"fa":120,"en":121},"هشدار جعبه‌ای: قطع زودهنگام خطر ترومبوز را بالا می‌برد؛ هماتوم نخاعی با بی‌حسی نخاعی.","Boxed warning: premature discontinuation raises thrombotic risk; spinal\u002Fepidural haematoma with neuraxial anaesthesia.",[123],{"source":34,"section":124},"Boxed Warning",[],[],[],[],{"status":130,"reviewer":131,"date":131},"unverified",null,[133,138],{"regimen":62,"formulation":53,"input":134,"expect":137},{"ageYears":135,"weightKg":136},70,80,{"perDose":56},{"regimen":86,"formulation":45,"input":139,"expect":141},{"ageYears":140,"weightKg":136},50,{"perDay":142},30,1792078540220]