[{"data":1,"prerenderedAt":257},["ShallowReactive",2],{"drug-rifampin":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":22,"regimens":45,"contraindications":119,"warnings":129,"renal":137,"monitoring":138,"interactions":139,"review":140,"examples":143,"atc":162,"iran":164,"links":200,"populations":218,"usApproval":252},"rifampin",1,{"fa":7,"en":8},"ریفامپین","Rifampin (rifampicin)","anti-infectives",{"fa":11,"en":12},"ریفامایسین (ضدسل)","Rifamycin (antituberculous)",[14],{"name":15,"market":16},"Rifadin","US",[18,19,20,21,7],"rifampicin","rifadin","ریفامپیسین","ریفادین",[23,37],{"id":24,"form":25,"route":26,"label":27,"concentration":28,"markets":32,"refs":33},"cap-150","capsule","oral","150 mg capsule",{"amount":29,"unit":30,"perUnit":25,"scored":31},150,"mg",false,[16],[34],{"source":35,"section":36},"fda-rifampin","How Supplied",{"id":38,"form":25,"route":26,"label":39,"concentration":40,"markets":42,"refs":43},"cap-300","300 mg capsule",{"amount":41,"unit":30,"perUnit":25,"scored":31},300,[16],[44],{"source":35,"section":36},[46,73,87,102],{"id":47,"disease":48,"label":49,"population":52,"type":56,"unit":30,"dose":57,"refs":59,"limits":62,"notes":66},"tb-adult","tuberculosis",{"fa":50,"en":51},"سل — بزرگسال: ۱۰ mg\u002Fkg یک بار در روز (حداکثر ۶۰۰ mg)","TB — adult: 10 mg\u002Fkg once daily (max 600 mg)",{"minAge":53},{"value":54,"unit":55},18,"year","weightBased",{"perKgPerDay":58,"dividedDoses":5},10,[60],{"source":35,"section":61},"Dosage and Administration — Tuberculosis",{"maxPerDay":63,"refs":64},600,[65],{"source":35,"section":61},[67],{"text":68,"refs":71},{"fa":69,"en":70},"ناشتا: ۱ ساعت قبل یا ۲ ساعت بعد غذا، با یک لیوان آب؛ همیشه همراه داروهای دیگر سل.","Empty stomach: 1 h before or 2 h after a meal with water; always with other TB drugs.",[72],{"source":35,"section":61},{"id":74,"disease":48,"label":75,"population":78,"type":56,"unit":30,"dose":80,"refs":82,"limits":84},"tb-child",{"fa":76,"en":77},"سل — کودک: ۱۰ تا ۲۰ mg\u002Fkg یک بار در روز (حداکثر ۶۰۰ mg)","TB — child: 10–20 mg\u002Fkg once daily (max 600 mg)",{"maxAge":79},{"value":54,"unit":55},{"perKgPerDay":58,"perKgPerDayMax":81,"dividedDoses":5},20,[83],{"source":35,"section":61},{"maxPerDay":63,"refs":85},[86],{"source":35,"section":61},{"id":88,"disease":89,"label":90,"population":93,"type":95,"unit":30,"dose":96,"refs":98,"durationDays":101},"mening-adult","meningococcal-carrier",{"fa":91,"en":92},"حامل مننگوکوک — بزرگسال: ۶۰۰ mg دو بار در روز، ۲ روز","Meningococcal carrier — adult: 600 mg twice daily, 2 days",{"minAge":94},{"value":54,"unit":55},"fixed",{"perDose":63,"dosesPerDay":97},2,[99],{"source":35,"section":100},"Dosage and Administration — Meningococcal Carriers",{"min":97,"max":97},{"id":103,"disease":89,"label":104,"population":107,"type":56,"unit":30,"dose":111,"refs":113,"limits":115,"durationDays":118},"mening-child",{"fa":105,"en":106},"حامل مننگوکوک — کودک ۱ ماه به بالا: ۱۰ mg\u002Fkg هر ۱۲ ساعت، ۲ روز","Meningococcal carrier — child ≥1 month: 10 mg\u002Fkg every 12 h, 2 days",{"minAge":108,"maxAge":110},{"value":5,"unit":109},"month",{"value":54,"unit":55},{"perKgPerDose":58,"intervalHours":112},12,[114],{"source":35,"section":100},{"maxPerDose":63,"refs":116},[117],{"source":35,"section":100},{"min":97,"max":97},[120],{"id":121,"severity":122,"text":123,"refs":126},"ci","block",{"fa":124,"en":125},"حساسیت به ریفامایسین‌ها؛ هم‌زمان با ساکویناویر\u002Fریتوناویر و برخی داروهای ضدویروس.","Hypersensitivity to rifamycins; with saquinavir\u002Fritonavir and certain antivirals.",[127],{"source":35,"section":128},"Contraindications",[130],{"text":131,"refs":134},{"fa":132,"en":133},"ادرار، خلط و اشک رنگی می‌شود و لنز تماسی نرم ممکن است برای همیشه رنگ بگیرد. قرص و سایر روش‌های هورمونی پیشگیری ممکن است کم‌اثر شوند.","Urine, sputum and tears may be discoloured and soft contact lenses permanently stained. Hormonal contraceptives may become less reliable.",[135],{"source":35,"section":136},"Precautions — Information for Patients",[],[],[],{"status":141,"reviewer":142,"date":142},"unverified",null,[144,149,153,157],{"regimen":47,"formulation":38,"input":145,"expect":148},{"ageYears":146,"weightKg":147},40,60,{"perDose":63,"tabletsPerDoseRounded":97},{"regimen":74,"formulation":24,"input":150,"expect":152},{"ageYears":58,"weightKg":151},30,{"perDose":41,"tabletsPerDoseRounded":97},{"regimen":88,"formulation":38,"input":154,"expect":156},{"ageYears":151,"weightKg":155},70,{"perDose":63},{"regimen":103,"formulation":24,"input":158,"expect":161},{"ageYears":159,"weightKg":160},4,15,{"perDose":29,"tabletsPerDoseRounded":5},[163],"J04AB02",{"status":165,"forms":166,"refs":195},"registered",[167,171,175,179,183,187,191],{"code":168,"en":169,"fa":170},"01101","RIFAMPICIN 150MG CAP","کپسول ریفامپیسین ۱۵۰ میلی‌گرم",{"code":172,"en":173,"fa":174},"01102","RIFAMPICIN 153MG\u002FML DROP ORAL","قطره خوراکی ریفامپیسین ۱۵۳ میلی‌گرم \u002F میلی‌لیتر",{"code":176,"en":177,"fa":178},"14626","RIFAMPICIN 20MG\u002FML 60ML SYRUP","شربت ریفامپیسین ۲۰ میلی‌گرم \u002F میلی‌لیتر ۶۰ میلی‌لیتر",{"code":180,"en":181,"fa":182},"01103","RIFAMPICIN 300MG CAP","کپسول ریفامپیسین ۳۰۰ میلی‌گرم",{"code":184,"en":185,"fa":186},"01100","RIFAMPICIN 600MG VIAL","ویال ریفامپیسین ۶۰۰ میلی‌گرم",{"code":188,"en":189,"fa":190},"52408","RIFAMPICIN SYRUP ORAL 20 mg\u002F1mL 60 mL","شربت ریفامپیسین ۲۰ میلی‌گرم \u002F ۱ میلی‌لیتر ۶۰ میلی‌لیتر",{"code":192,"en":193,"fa":194},"53021","RIFAMPICIN SUSPENSION ORAL 20 mg\u002F1mL 200 mL","سوسپانسیون خوراکی ریفامپیسین ۲۰ میلی‌گرم \u002F ۱ میلی‌لیتر ۲۰۰ میلی‌لیتر",[196],{"source":197,"section":198,"url":199},"darooyab-generic","G-492\u002FRifampin","https:\u002F\u002Fwww.darooyab.ir\u002FG-492\u002FRifampin",[201,205,209,213,216],{"kind":202,"url":203,"label":204},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=219918","ANDA219918",{"kind":206,"url":207,"label":208},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=b389b1a3-672f-47e3-916c-4a9c044b211b","FDA Rifampin caps.",{"kind":210,"url":211,"label":212},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa682403.html","Rifampin",{"kind":214,"url":215,"label":163},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=J04AB02",{"kind":217,"url":199,"label":212},"darooyab",{"pregnancy":219,"lactation":228,"pediatric":236,"geriatric":244},{"level":220,"text":221,"quote":224,"refs":225},"caution",{"fa":222,"en":223},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Nevertheless, because the studies in humans cannot rule out the possibility of harm, rifampin should be used during pregnancy only if the potential benefit outweighs the potential risk to the fetus.",[226],{"source":35,"section":227},"PREGNANCY",{"level":220,"text":229,"quote":232,"refs":233},{"fa":230,"en":231},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Because of the potential for tumorigenicity shown for rifampin in animal studies, a decision should be made whether to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.",[234],{"source":35,"section":235},"NURSING MOTHERS",{"level":220,"text":237,"quote":240,"refs":241},{"fa":238,"en":239},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","See CLINICAL PHARMACOLOGY–Pediatrics; see also DOSAGE AND ADMINISTRATION.",[242],{"source":35,"section":243},"PEDIATRIC USE",{"level":220,"text":245,"quote":248,"refs":249},{"fa":246,"en":247},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Caution should therefore be observed in using rifampin in elderly patients.",[250],{"source":35,"section":251},"GERIATRIC USE",{"kind":253,"refs":254,"id":204},"ANDA",[255],{"source":35,"section":256},"SPL approval \u002F marketing category",1792092043944]