[{"data":1,"prerenderedAt":166},["ShallowReactive",2],{"drug-rabies-vaccine":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":21,"regimens":34,"contraindications":67,"warnings":76,"renal":77,"monitoring":78,"interactions":79,"review":80,"examples":83,"atc":94,"iran":96,"links":112,"populations":127,"usApproval":161},"rabies-vaccine",1,{"fa":7,"en":8},"واکسن هاری","Rabies vaccine","anti-infectives",{"fa":11,"en":12},"واکسن غیرفعال","Inactivated vaccine",[14],{"name":15,"market":16},"Imovax Rabies","US",[18,19,7,20],"imovax","rabavert","verorab",[22],{"id":23,"form":24,"route":25,"label":26,"concentration":27,"markets":29,"refs":30},"vial-1","injection","im","1 mL dose after reconstitution",{"amount":5,"unit":28,"perVolumeMl":5},"mL",[16],[31],{"source":32,"section":33},"fda-imovax","3",[35,55],{"id":36,"disease":37,"label":38,"population":41,"type":42,"unit":28,"dose":43,"refs":44,"durationDays":47,"notes":48},"pep","rabies-exposure",{"fa":39,"en":40},"پیشگیری پس از تماس — ۱ mL عضلانی در روزهای ۰، ۳، ۷، ۱۴ و ۲۸ (همه سنین)","Post-exposure — 1 mL IM on days 0, 3, 7, 14 and 28 (all ages)",{},"fixed",{"perDose":5,"dosesPerDay":5},[45],{"source":32,"section":46},"2.2",{"min":5,"max":5},[49],{"text":50,"refs":53},{"fa":51,"en":52},"افراد واکسن‌نزده یا با نقص ایمنی: روزهای ۰، ۳، ۷، ۱۴ و ۲۸ همراه ایمونوگلوبولین هاری در روز ۰. افرادی که قبلاً واکسن کامل زده‌اند: فقط روز ۰ و ۳، بدون ایمونوگلوبولین. دور از محل تزریق ایمونوگلوبولین.","Unvaccinated or immunosuppressed: days 0, 3, 7, 14 and 28, with rabies immune globulin on day 0. Previously vaccinated: days 0 and 3 only, no immune globulin. Away from the immune globulin site.",[54],{"source":32,"section":46},{"id":56,"disease":57,"label":58,"population":61,"type":42,"unit":28,"dose":62,"refs":63,"durationDays":66},"prep","immunization",{"fa":59,"en":60},"پیشگیری پیش از تماس — ۱ mL عضلانی روز ۰ و ۷ (یا ۰، ۷ و ۲۱\u002F۲۸)","Pre-exposure — 1 mL IM on days 0 and 7 (or 0, 7 and 21\u002F28)",{},{"perDose":5,"dosesPerDay":5},[64],{"source":32,"section":65},"2.1",{"min":5,"max":5},[68],{"id":56,"severity":69,"text":70,"refs":73},"warn",{"fa":71,"en":72},"پیشگیری پیش از تماس: حساسیت سیستمیک تهدیدکننده حیات به اجزای واکسن. پس از تماس منع مصرف ندارد.","Pre-exposure: life-threatening systemic hypersensitivity to a component. No contraindication after exposure.",[74],{"source":32,"section":75},"4",[],[],[],[],{"status":81,"reviewer":82,"date":82},"unverified",null,[84,89],{"regimen":36,"formulation":23,"input":85,"expect":88},{"ageYears":86,"weightKg":87},8,25,{"perDose":5,"mlPerDose":5},{"regimen":56,"formulation":23,"input":90,"expect":93},{"ageYears":91,"weightKg":92},30,70,{"perDose":5,"mlPerDose":5},[95],"J07BG01",{"status":97,"forms":98,"refs":107},"registered",[99,103],{"code":100,"en":101,"fa":102},"14051","VACCINE-RABIES PCEC VIAL","ویال واکسن–هاری پسک",{"code":104,"en":105,"fa":106},"52107","RABIES VACCINE INJECTION, POWDER, FOR SUSPENSION PARENTERAL 2.5 [iU] 1 mL","پودر برای تهیه سوسپانسیون تزریقی واکسن هاری ۲٫۵ واحد بین‌المللی ۱ میلی‌لیتر",[108],{"source":109,"section":110,"url":111},"darooyab-generic","G-3505\u002FRabies-Vaccines","https:\u002F\u002Fwww.darooyab.ir\u002FG-3505\u002FRabies-Vaccines",[113,117,121,124],{"kind":114,"url":115,"label":116},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=103931","BLA103931",{"kind":118,"url":119,"label":120},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=ba8d4e72-f452-4859-ae6f-3644b4b0a78c","FDA Imovax Rabies",{"kind":122,"url":123,"label":95},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=J07BG01",{"kind":125,"url":111,"label":126},"darooyab","Rabies-Vaccines",{"pregnancy":128,"lactation":137,"pediatric":145,"geriatric":153},{"level":129,"text":130,"quote":133,"refs":134},"caution",{"fa":131,"en":132},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary All pregnancies have a risk of birth defect, loss, or other adverse outcomes.",[135],{"source":32,"section":136},"8.1",{"level":129,"text":138,"quote":141,"refs":142},{"fa":139,"en":140},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Data are not available to assess the effects of IMOVAX RABIES on the breastfed infant or on milk production\u002Fexcretion.",[143],{"source":32,"section":144},"8.2",{"level":129,"text":146,"quote":149,"refs":150},{"fa":147,"en":148},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","Safety and efficacy have been established in all pediatric age groups [See Adverse Reactions (6.1) and Clinical Studies (14) ] .",[151],{"source":32,"section":152},"8.4",{"level":129,"text":154,"quote":157,"refs":158},{"fa":155,"en":156},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Clinical studies of IMOVAX RABIES did not include sufficient numbers of participants aged 65 and over to determine whether they respond differently from younger participants [See Adverse Reactions (6.1) and Clinical Studies (14) ] .",[159],{"source":32,"section":160},"8.5",{"kind":162,"refs":163,"id":116},"BLA",[164],{"source":32,"section":165},"SPL approval \u002F marketing category",1792108435708]