[{"data":1,"prerenderedAt":230},["ShallowReactive",2],{"drug-rabeprazole":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":21,"regimens":36,"contraindications":114,"warnings":124,"renal":125,"monitoring":126,"interactions":127,"review":135,"examples":138,"atc":156,"iran":158,"links":174,"populations":191,"usApproval":225},"rabeprazole",1,{"fa":7,"en":8},"رابپرازول","Rabeprazole","alimentary-metabolism",{"fa":11,"en":12},"مهارکننده پمپ پروتون","Proton pump inhibitor",[14],{"name":15,"market":16},"Aciphex","US",[18,19,7,20],"aciphex","pariet","پاریت",[22],{"id":23,"form":24,"route":25,"label":26,"concentration":27,"markets":31,"refs":32},"tab-20","tablet","oral","20 mg delayed-release tablet (swallow whole)",{"amount":28,"unit":29,"perUnit":24,"scored":30},20,"mg",false,[16],[33],{"source":34,"section":35},"fda-rabeprazole","3",[37,62,81,93],{"id":38,"disease":39,"label":40,"population":43,"type":47,"unit":29,"dose":48,"refs":49,"durationDays":52,"notes":55},"erosive","erosive-esophagitis",{"fa":41,"en":42},"ازوفاژیت اروزیو — ۲۰ mg روزانه ۴ تا ۸ هفته","Erosive GERD — 20 mg daily for 4–8 weeks",{"minAge":44},{"value":45,"unit":46},18,"year","fixed",{"perDose":28,"dosesPerDay":5},[50],{"source":34,"section":51},"2",{"min":53,"max":54},28,56,[56],{"text":57,"refs":60},{"fa":58,"en":59},"نگهدارنده پس از بهبود: ۲۰ mg روزانه. قرص کامل بلعیده شود.","Maintenance of healing: 20 mg daily. Swallow whole.",[61],{"source":34,"section":51},{"id":63,"disease":63,"label":64,"population":67,"type":47,"unit":29,"dose":70,"refs":71,"durationDays":73,"notes":74},"gerd",{"fa":65,"en":66},"ریفلاکس علامت‌دار (۱۲ سال به بالا) — ۲۰ mg روزانه تا ۴ هفته","Symptomatic GERD (≥12 y) — 20 mg daily up to 4 weeks",{"minAge":68},{"value":69,"unit":46},12,{"perDose":28,"dosesPerDay":5},[72],{"source":34,"section":51},{"min":53,"max":54},[75],{"text":76,"refs":79},{"fa":77,"en":78},"نوجوان ۱۲ سال به بالا: تا ۸ هفته.","Adolescents ≥12 y: up to 8 weeks.",[80],{"source":34,"section":51},{"id":82,"disease":83,"label":84,"population":87,"type":47,"unit":29,"dose":89,"refs":90,"durationDays":92},"du","peptic-ulcer-disease",{"fa":85,"en":86},"زخم دوازدهه — ۲۰ mg روزانه پس از صبحانه تا ۴ هفته","Duodenal ulcer — 20 mg daily after the morning meal up to 4 weeks",{"minAge":88},{"value":45,"unit":46},{"perDose":28,"dosesPerDay":5},[91],{"source":34,"section":51},{"min":53,"max":53},{"id":94,"disease":95,"label":96,"population":99,"type":47,"unit":29,"dose":101,"refs":103,"durationDays":105,"notes":107},"hp","h-pylori",{"fa":97,"en":98},"ریشه‌کنی هلیکوباکتر — ۲۰ mg دو بار در روز + آموکسی‌سیلین ۱ g + کلاریترومایسین ۵۰۰ mg، ۷ روز","H. pylori eradication — 20 mg twice daily + amoxicillin 1 g + clarithromycin 500 mg, 7 days",{"minAge":100},{"value":45,"unit":46},{"perDose":28,"dosesPerDay":102},2,[104],{"source":34,"section":51},{"min":106,"max":106},7,[108],{"text":109,"refs":112},{"fa":110,"en":111},"هر سه دارو دو بار در روز با صبحانه و شام.","All three drugs twice daily with morning and evening meals.",[113],{"source":34,"section":51},[115],{"id":116,"severity":117,"text":118,"refs":121},"ci","block",{"fa":119,"en":120},"حساسیت به رابپرازول یا بنزیمیدازول‌های جایگزین‌شده؛ مصرف همزمان ریلپیویرین.","Hypersensitivity to rabeprazole or substituted benzimidazoles; concomitant rilpivirine.",[122],{"source":34,"section":123},"4",[],[],[],[128],{"with":129,"text":130,"refs":133},"rilpivirine",{"fa":131,"en":132},"ریلپیویرین: منع مصرف همزمان.","Rilpivirine: contraindicated.",[134],{"source":34,"section":123},{"status":136,"reviewer":137,"date":137},"unverified",null,[139,144,148,152],{"regimen":38,"formulation":23,"input":140,"expect":143},{"ageYears":141,"weightKg":142},50,70,{"perDose":28,"tabletsPerDoseRounded":5},{"regimen":94,"formulation":23,"input":145,"expect":147},{"ageYears":146,"weightKg":142},40,{"perDose":28,"tabletsPerDoseRounded":5},{"regimen":82,"formulation":23,"input":149,"expect":151},{"ageYears":150,"weightKg":142},45,{"perDose":28,"tabletsPerDoseRounded":5},{"regimen":63,"formulation":23,"input":153,"expect":155},{"ageYears":154,"weightKg":141},14,{"perDose":28,"tabletsPerDoseRounded":5},[157],"A02BC04",{"status":159,"forms":160,"refs":169},"registered",[161,165],{"code":162,"en":163,"fa":164},"07173","RABEPRAZOLE 10MG TAB","قرص رابپرازول ۱۰ میلی‌گرم",{"code":166,"en":167,"fa":168},"06438","RABEPRAZOLE 20MG TAB","قرص رابپرازول ۲۰ میلی‌گرم",[170],{"source":171,"section":172,"url":173},"darooyab-generic","G-2636\u002FRabeprazole","https:\u002F\u002Fwww.darooyab.ir\u002FG-2636\u002FRabeprazole",[175,179,183,186,189],{"kind":176,"url":177,"label":178},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=208644","ANDA208644",{"kind":180,"url":181,"label":182},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=45092108-7c4a-48f9-8222-ca8612e82189","FDA Rabeprazole",{"kind":184,"url":185,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa699060.html",{"kind":187,"url":188,"label":157},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=A02BC04",{"kind":190,"url":173,"label":8},"darooyab",{"pregnancy":192,"lactation":201,"pediatric":209,"geriatric":217},{"level":193,"text":194,"quote":197,"refs":198},"caution",{"fa":195,"en":196},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary There are no available human data on rabeprazole sodium delayed-release tablets use in pregnant women to inform the drug associated risk.",[199],{"source":34,"section":200},"8.1",{"level":193,"text":202,"quote":205,"refs":206},{"fa":203,"en":204},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary Lactation studies have not been conducted to assess the presence of rabeprazole in human milk, the effects of rabeprazole on the breastfed infant, or the effects of rabeprazole on milk production.",[207],{"source":34,"section":208},"8.2",{"level":193,"text":210,"quote":213,"refs":214},{"fa":211,"en":212},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","The safety and effectiveness of rabeprazole sodium delayed-release tablets have been established in pediatric patients for adolescent patients 12 years of age and older for the treatment of symptomatic GERD.",[215],{"source":34,"section":216},"8.4",{"level":193,"text":218,"quote":221,"refs":222},{"fa":219,"en":220},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Of the total number of subjects (n=2,009) in clinical studies of rabeprazole sodium delayed-release tablets, 19% were 65 years and over, while 4% were 75 years and over.",[223],{"source":34,"section":224},"8.5",{"kind":226,"refs":227,"id":178},"ANDA",[228],{"source":34,"section":229},"SPL approval \u002F marketing category",1792115194049]