[{"data":1,"prerenderedAt":112},["ShallowReactive",2],{"drug-propylthiouracil":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":20,"regimens":35,"contraindications":81,"warnings":91,"renal":99,"monitoring":100,"interactions":101,"review":102,"examples":105},"propylthiouracil",1,{"fa":7,"en":8},"پروپیل‌تیواوراسیل","Propylthiouracil (PTU)","endocrine",{"fa":11,"en":12},"ضدتیروئید","Antithyroid",[14],{"name":15,"market":16},"PTU","US",[15,18,19],"پی تی یو","پروپیل تیواوراسیل",[21],{"id":22,"form":23,"route":24,"label":25,"concentration":26,"markets":30,"refs":31},"tab-50","tablet","oral","50 mg tablet (scored)",{"amount":27,"unit":28,"perUnit":23,"scored":29},50,"mg",true,[16],[32],{"source":33,"section":34},"fda-ptu","How Supplied",[36,64],{"id":37,"disease":38,"label":39,"population":42,"type":46,"unit":28,"dose":47,"refs":50,"notes":53},"adult","hyperthyroidism",{"fa":40,"en":41},"پرکاری تیروئید — بزرگسال: ۳۰۰ mg\u002Fday در ۳ نوبت","Hyperthyroidism — adults: 300 mg\u002Fday in 3 doses",{"minAge":43},{"value":44,"unit":45},18,"year","fixed",{"perDose":48,"dosesPerDay":49},100,3,[51],{"source":33,"section":52},"Dosage and Administration, Adults",[54],{"text":55,"refs":58},{"fa":56,"en":57},"هر ۸ ساعت. شدید یا گواتر بزرگ: ۴۰۰ mg\u002Fday (گاهی ۶۰۰ تا ۹۰۰). نگهدارنده ۱۰۰ تا ۱۵۰ mg\u002Fday. ممکن است در سه‌ماهه اول بارداری ارجح باشد.","Every 8 hours. Severe or large goitre: 400 mg\u002Fday (occasionally 600–900). Maintenance 100–150 mg\u002Fday. May be preferred in the first trimester of pregnancy.",[59,60,62],{"source":33,"section":52},{"source":33,"section":61},"Dosage and Administration",{"source":33,"section":63},"Indications and Usage",{"id":65,"disease":38,"label":66,"population":69,"type":71,"unit":28,"dose":72,"refs":76},"peds",{"fa":67,"en":68},"کودکان","Children",{"maxAge":70},{"value":44,"unit":45},"notCalculated",{"reason":73},{"fa":74,"en":75},"به‌علت آسیب شدید کبدی در کودکان توصیه نمی‌شود، مگر وقتی متی‌مازول تحمل نشود و جراحی یا ید رادیواکتیو مناسب نباشد.","Not recommended in children because of severe liver injury, except when methimazole is not tolerated and surgery or radioiodine are unsuitable.",[77,79],{"source":33,"section":78},"Dosage and Administration, Pediatric Patients",{"source":33,"section":80},"Pediatric Use",[82],{"id":83,"severity":84,"text":85,"refs":88},"ci","block",{"fa":86,"en":87},"حساسیت به دارو.","Hypersensitivity to the drug.",[89],{"source":33,"section":90},"Contraindications",[92],{"text":93,"refs":96},{"fa":94,"en":95},"سمیت کبدی: نارسایی کبد، پیوند یا مرگ در بزرگسالان و کودکان گزارش شده است.","Liver toxicity: liver failure, transplantation or death reported in adults and children.",[97],{"source":33,"section":98},"Warnings, Liver Toxicity",[],[],[],{"status":103,"reviewer":104,"date":104},"unverified",null,[106],{"regimen":37,"formulation":22,"input":107,"expect":110},{"ageYears":108,"weightKg":109},40,65,{"perDose":48,"tabletsPerDoseRounded":111},2,1792078539938]