[{"data":1,"prerenderedAt":168},["ShallowReactive",2],{"drug-pilocarpine-presbyopia":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":22,"regimens":35,"contraindications":58,"warnings":68,"renal":76,"monitoring":77,"interactions":78,"review":79,"examples":82,"atc":88,"iran":90,"links":114,"populations":129,"usApproval":163},"pilocarpine-presbyopia",1,{"fa":7,"en":8},"پیلوکارپین ۱٫۲۵٪ (پیرچشمی)","Pilocarpine 1.25% (presbyopia)","sensory-organs",{"fa":11,"en":12},"کولینرژیک (میوتیک)","Cholinergic (miotic)",[14],{"name":15,"market":16},"Vuity","US",[18,19,20,21],"vuity","ویوتی","pilocarpine","پیلوکارپین",[23],{"id":24,"form":25,"route":26,"label":27,"concentration":28,"markets":30,"refs":31},"drops","eye-drops","ophthalmic","1.25% eye drops",{"amount":5,"unit":29,"perUnit":29},"drop",[16],[32],{"source":33,"section":34},"fda-pilocarpine-125","3",[36],{"id":37,"disease":38,"label":39,"population":42,"type":46,"unit":29,"dose":47,"refs":48,"notes":51},"presb","presbyopia",{"fa":40,"en":41},"پیرچشمی بزرگسال — یک قطره در هر چشم یک بار در روز","Presbyopia, adults — 1 drop in each eye once daily",{"minAge":43},{"value":44,"unit":45},18,"year","fixed",{"perDose":5,"dosesPerDay":5},[49],{"source":33,"section":50},"2",[52],{"text":53,"refs":56},{"fa":54,"en":55},"با سایر قطره‌های چشمی دست‌کم ۵ دقیقه فاصله.","Separate other eye drops by at least 5 min.",[57],{"source":33,"section":50},[59],{"id":60,"severity":61,"text":62,"refs":65},"hyper","block",{"fa":63,"en":64},"حساسیت به پیلوکارپین.","Hypersensitivity to pilocarpine.",[66],{"source":33,"section":67},"4",[69],{"text":70,"refs":73},{"fa":71,"en":72},"تاری دید و دید کم در نور ضعیف (رانندگی شبانه با احتیاط)؛ خطر جداشدگی شبکیه؛ ایریت.","Blurred vision and poor dim-light vision (caution driving at night); risk of retinal detachment; iritis.",[74],{"source":33,"section":75},"5",[],[],[],{"status":80,"reviewer":81,"date":81},"unverified",null,[83],{"regimen":37,"formulation":24,"input":84,"expect":87},{"ageYears":85,"weightKg":86},50,70,{"perDose":5},[89],"S01EB01",{"status":91,"forms":92,"refs":109},"registered",[93,97,101,105],{"code":94,"en":95,"fa":96},"01006","PILOCARPINE 1% 10ML OPH DROP","قطره چشمی پیلوکارپین ۱ درصد ۱۰ میلی‌لیتر",{"code":98,"en":99,"fa":100},"01007","PILOCARPINE 2% 10ML OPH DROP","قطره چشمی پیلوکارپین ۲ درصد ۱۰ میلی‌لیتر",{"code":102,"en":103,"fa":104},"01008","PILOCARPINE 4% 10ML OPH DROP","قطره چشمی پیلوکارپین ۴ درصد ۱۰ میلی‌لیتر",{"code":106,"en":107,"fa":108},"06016","PILOCARPINE 5MG TAB","قرص پیلوکارپین ۵ میلی‌گرم",[110],{"source":111,"section":112,"url":113},"darooyab-generic","G-3052\u002FPilocarpine","https:\u002F\u002Fwww.darooyab.ir\u002FG-3052\u002FPilocarpine",[115,119,123,126],{"kind":116,"url":117,"label":118},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=217733","ANDA217733",{"kind":120,"url":121,"label":122},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=93e37b61-7b90-4740-b0b4-17d39d3b03f6","FDA Pilocarpine 1.25%",{"kind":124,"url":125,"label":89},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=S01EB01",{"kind":127,"url":113,"label":128},"darooyab","Pilocarpine",{"pregnancy":130,"lactation":139,"pediatric":147,"geriatric":155},{"level":131,"text":132,"quote":135,"refs":136},"caution",{"fa":133,"en":134},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary There are no adequate and well-controlled studies of pilocarpine hydrochloride ophthalmic solution administration in pregnant women to inform a drug-associated risk.",[137],{"source":33,"section":138},"8.1",{"level":131,"text":140,"quote":143,"refs":144},{"fa":141,"en":142},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary There is no information regarding the presence of pilocarpine in human milk, the effects on the breastfed infants or the effects on milk production to inform risk of pilocarpine hydrochloride ophthalmic solution to an infant during lactation.",[145],{"source":33,"section":146},"8.2",{"level":131,"text":148,"quote":151,"refs":152},{"fa":149,"en":150},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","Presbyopia does not occur in the pediatric population.",[153],{"source":33,"section":154},"8.4",{"level":131,"text":156,"quote":159,"refs":160},{"fa":157,"en":158},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Clinical studies of pilocarpine hydrochloride ophthalmic solution did not include participants aged 65 and over to determine whether they respond differently from younger participants.",[161],{"source":33,"section":162},"8.5",{"kind":164,"refs":165,"id":118},"ANDA",[166],{"source":33,"section":167},"SPL approval \u002F marketing category",1792191561342]