[{"data":1,"prerenderedAt":214},["ShallowReactive",2],{"drug-naproxen":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":12,"synonyms":16,"formulations":20,"regimens":52,"contraindications":158,"warnings":177,"renal":178,"monitoring":179,"interactions":180,"review":181,"examples":184},"naproxen",1,{"fa":7,"en":8},"ناپروکسن","Naproxen","analgesics",{"fa":11,"en":11},"NSAID",[13],{"name":14,"market":15},"Naprosyn","US",[17,18,7,19],"naprosyn","ناپروسین","ناپروکسین",[21,35,43],{"id":22,"form":23,"route":24,"label":25,"concentration":26,"markets":30,"refs":31},"tab-250","tablet","oral","250 mg tablet",{"amount":27,"unit":28,"perUnit":23,"scored":29},250,"mg",false,[15],[32],{"source":33,"section":34},"fda-naproxen","3",{"id":36,"form":23,"route":24,"label":37,"concentration":38,"markets":40,"refs":41},"tab-375","375 mg tablet",{"amount":39,"unit":28,"perUnit":23,"scored":29},375,[15],[42],{"source":33,"section":34},{"id":44,"form":23,"route":24,"label":45,"concentration":46,"markets":49,"refs":50},"tab-500","500 mg tablet (scored)",{"amount":47,"unit":28,"perUnit":23,"scored":48},500,true,[15],[51],{"source":33,"section":34},[53,80,93,114,133],{"id":54,"disease":54,"label":55,"population":58,"type":62,"unit":28,"dose":63,"refs":66,"limits":69,"notes":73},"pain",{"fa":56,"en":57},"درد، دیسمنوره، تاندونیت\u002Fبورسیت — بزرگسال: ۲۵۰ mg هر ۶ تا ۸ ساعت (دوز اول ۵۰۰)","Pain, dysmenorrhoea, tendonitis\u002Fbursitis — adults: 250 mg every 6–8 h (first dose 500)",{"minAge":59},{"value":60,"unit":61},18,"year","fixed",{"perDose":27,"dosesPerDay":64,"intervalHours":65},4,6,[67],{"source":33,"section":68},"2.4",{"maxPerDay":70,"refs":71},1250,[72],{"source":33,"section":68},[74],{"text":75,"refs":78},{"fa":76,"en":77},"دوز اول ۵۰۰ mg، سپس ۲۵۰ mg هر ۶ تا ۸ ساعت در صورت نیاز؛ حداکثر ۱۲۵۰ mg\u002Fday.","First dose 500 mg, then 250 mg every 6–8 h as needed; max 1,250 mg\u002Fday.",[79],{"source":33,"section":68},{"id":81,"disease":81,"label":82,"population":85,"type":62,"unit":28,"dose":87,"refs":88,"limits":90},"dysmenorrhea",{"fa":83,"en":84},"دیسمنوره اولیه — ۲۵۰ mg هر ۶ تا ۸ ساعت (دوز اول ۵۰۰)","Primary dysmenorrhoea — 250 mg every 6–8 h (first dose 500)",{"minAge":86},{"value":60,"unit":61},{"perDose":27,"dosesPerDay":64,"intervalHours":65},[89],{"source":33,"section":68},{"maxPerDay":70,"refs":91},[92],{"source":33,"section":68},{"id":94,"disease":95,"label":96,"population":99,"type":62,"unit":28,"dose":101,"refs":103,"notes":106},"arthritis","osteoarthritis",{"fa":97,"en":98},"آرتروز، آرتریت روماتوئید، اسپوندیلیت — ۲۵۰ تا ۵۰۰ mg دو بار در روز","OA, RA, ankylosing spondylitis — 250–500 mg twice daily",{"minAge":100},{"value":60,"unit":61},{"perDose":27,"perDoseMax":47,"dosesPerDay":102},2,[104],{"source":33,"section":105},"2.1, Table 1",[107],{"text":108,"refs":111},{"fa":109,"en":110},"در صورت تحمل تا ۱۵۰۰ mg\u002Fday حداکثر ۶ ماه.","If tolerated up to 1,500 mg\u002Fday for up to 6 months.",[112],{"source":33,"section":113},"2.2",{"id":115,"disease":115,"label":116,"population":119,"type":62,"unit":28,"dose":121,"refs":123,"notes":126},"gout",{"fa":117,"en":118},"حمله حاد نقرس — ۷۵۰ mg، سپس ۲۵۰ mg هر ۸ ساعت","Acute gout — 750 mg, then 250 mg every 8 h",{"minAge":120},{"value":60,"unit":61},{"perDose":27,"dosesPerDay":122},3,[124],{"source":33,"section":125},"2.5",[127],{"text":128,"refs":131},{"fa":129,"en":130},"دوز اول ۷۵۰ mg؛ ادامه تا فروکش حمله.","First dose 750 mg; continue until the attack subsides.",[132],{"source":33,"section":125},{"id":134,"disease":135,"label":136,"population":139,"type":143,"unit":28,"dose":144,"refs":146,"notes":151},"jia","juvenile-arthritis",{"fa":137,"en":138},"آرتریت ایدیوپاتیک نوجوانان — ۵۰ kg به بالا: حدود ۱۰ mg\u002Fkg\u002Fday در ۲ نوبت","Juvenile idiopathic arthritis — ≥50 kg: about 10 mg\u002Fkg\u002Fday in 2 doses",{"minAge":140,"maxAge":141,"minWeightKg":142},{"value":102,"unit":61},{"value":60,"unit":61},50,"weightBased",{"perKgPerDay":145,"dividedDoses":102},10,[147,149],{"source":33,"section":148},"2.3",{"source":33,"section":150},"2",[152],{"text":153,"refs":156},{"fa":154,"en":155},"قرص برای کودکان زیر ۵۰ kg مناسب نیست (سوسپانسیون).","Tablets are not appropriate for children under 50 kg (use suspension).",[157],{"source":33,"section":148},[159,168],{"id":160,"severity":161,"text":162,"refs":165},"ci","block",{"fa":163,"en":164},"حساسیت به دارو؛ سابقه آسم، کهیر یا واکنش آلرژیک پس از آسپیرین یا NSAID؛ هنگام جراحی بای‌پس عروق کرونر (CABG).","Hypersensitivity; history of asthma, urticaria or allergic-type reaction after aspirin or other NSAIDs; in the setting of CABG surgery.",[166],{"source":33,"section":167},"4",{"id":169,"severity":170,"text":171,"refs":174},"boxed","warn",{"fa":172,"en":173},"هشدار جعبه‌ای: خطر حوادث قلبی‌عروقی ترومبوتیک و خونریزی، زخم و سوراخ‌شدگی گوارشی.","Boxed warning: risk of serious cardiovascular thrombotic events and GI bleeding, ulceration and perforation.",[175],{"source":33,"section":176},"Boxed Warning",[],[],[],[],{"status":182,"reviewer":183,"date":183},"unverified",null,[185,191,196,201,206,210],{"regimen":54,"formulation":22,"input":186,"expect":189},{"ageYears":187,"weightKg":188},30,70,{"perDose":27,"perDay":190},1000,{"regimen":81,"formulation":22,"input":192,"expect":195},{"ageYears":193,"weightKg":194},20,55,{"perDose":27},{"regimen":94,"formulation":22,"input":197,"expect":200},{"ageYears":198,"weightKg":199},60,75,{"perDose":27,"upperPerDose":47},{"regimen":115,"formulation":22,"input":202,"expect":204},{"ageYears":142,"weightKg":203},85,{"perDay":205},750,{"regimen":134,"formulation":22,"input":207,"expect":209},{"ageYears":208,"weightKg":142},15,{"perDose":27},{"regimen":134,"formulation":22,"input":211,"expect":212},{"ageYears":145,"weightKg":187},{"status":213},"blocked",1792078538439]