[{"data":1,"prerenderedAt":111},["ShallowReactive",2],{"drug-medroxyprogesterone":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":22,"regimens":37,"contraindications":74,"warnings":93,"renal":94,"monitoring":95,"interactions":96,"review":97,"examples":100},"medroxyprogesterone",1,{"fa":7,"en":8},"مدروکسی‌پروژسترون","Medroxyprogesterone acetate","womens-health",{"fa":11,"en":12},"پروژستین","Progestin",[14],{"name":15,"market":16},"Provera","US",[18,19,20,21],"provera","پروورا","مدروکسی پروژسترون","MPA",[23],{"id":24,"form":25,"route":26,"label":27,"concentration":28,"markets":32,"refs":33},"tab-10","tablet","oral","10 mg tablet (scored)",{"amount":29,"unit":30,"perUnit":25,"scored":31},10,"mg",true,[16],[34],{"source":35,"section":36},"fda-medroxyprogesterone","How Supplied",[38,62],{"id":39,"disease":40,"label":41,"population":44,"type":48,"unit":30,"dose":49,"refs":50,"durationDays":53,"notes":55},"amenorrhea","secondary-amenorrhea",{"fa":42,"en":43},"آمنوره ثانویه: ۵ یا ۱۰ mg روزانه، ۵ تا ۱۰ روز","Secondary amenorrhoea: 5 or 10 mg daily for 5–10 days",{"minAge":45},{"value":46,"unit":47},12,"year","fixed",{"perDose":29,"dosesPerDay":5},[51],{"source":35,"section":52},"Dosage and Administration",{"min":54,"max":29},5,[56],{"text":57,"refs":60},{"fa":58,"en":59},"برای تبدیل ترشحی بهینه آندومتر: ۱۰ mg روزانه ۱۰ روز. خونریزی قطع معمولاً ۳ تا ۷ روز پس از توقف.","For optimal secretory transformation: 10 mg daily for 10 days. Withdrawal bleeding usually 3–7 days after stopping.",[61],{"source":35,"section":52},{"id":63,"disease":64,"label":65,"population":68,"type":48,"unit":30,"dose":70,"refs":71,"durationDays":73},"aub","abnormal-uterine-bleeding",{"fa":66,"en":67},"خونریزی غیرطبیعی رحم (هورمونی): ۵ یا ۱۰ mg روزانه ۵ تا ۱۰ روز از روز ۱۶ یا ۲۱ سیکل","Abnormal uterine bleeding (hormonal): 5 or 10 mg daily for 5–10 days from cycle day 16 or 21",{"minAge":69},{"value":46,"unit":47},{"perDose":29,"dosesPerDay":5},[72],{"source":35,"section":52},{"min":54,"max":29},[75,84],{"id":76,"severity":77,"text":78,"refs":81},"ci","block",{"fa":79,"en":80},"خونریزی تناسلی تشخیص‌داده‌نشده؛ سرطان پستان یا نئوپلازی وابسته به هورمون؛ DVT\u002FPE یا ترومبوآمبولی شریانی (فعلی یا سابقه)؛ بیماری کبد؛ بارداری؛ آنافیلاکسی به دارو.","Undiagnosed genital bleeding; breast cancer or hormone-dependent neoplasia; current or past DVT\u002FPE or arterial thromboembolism; liver disease; pregnancy; anaphylaxis to the drug.",[82],{"source":35,"section":83},"Contraindications",{"id":85,"severity":86,"text":87,"refs":90},"boxed","warn",{"fa":88,"en":89},"هشدار جعبه‌ای: با استروژن خطر DVT، PE، سکته، MI، سرطان پستان و دمانس در زنان یائسه.","Boxed warning: with oestrogen, increased risk of DVT, PE, stroke, MI, breast cancer and dementia in postmenopausal women.",[91],{"source":35,"section":92},"Boxed Warning",[],[],[],[],{"status":98,"reviewer":99,"date":99},"unverified",null,[101,106],{"regimen":39,"formulation":24,"input":102,"expect":105},{"ageYears":103,"weightKg":104},25,60,{"perDose":29},{"regimen":63,"formulation":24,"input":107,"expect":110},{"ageYears":108,"weightKg":109},35,65,{"perDose":29},1792078537605]