[{"data":1,"prerenderedAt":192},["ShallowReactive",2],{"drug-medroxyprogesterone-injection":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":22,"regimens":36,"contraindications":58,"warnings":68,"renal":76,"monitoring":77,"interactions":78,"review":79,"examples":82,"atc":88,"iran":90,"links":126,"populations":145,"usApproval":187},"medroxyprogesterone-injection",1,{"fa":7,"en":8},"مدروکسی‌پروژسترون تزریقی (دپو)","Medroxyprogesterone injection (Depo)","genitourinary-sex-hormones",{"fa":11,"en":12},"پروژستین ضدبارداری","Progestin contraceptive",[14],{"name":15,"market":16},"Depo-Provera CI","US",[18,19,20,21],"depo provera","دپو پروورا","آمپول ضد بارداری","آمپول سه ماهه",[23],{"id":24,"form":25,"route":26,"label":27,"concentration":28,"markets":31,"refs":32},"vial-150","injection","im","150 mg\u002FmL vial or prefilled syringe",{"amount":29,"unit":30,"perVolumeMl":5},150,"mg",[16],[33],{"source":34,"section":35},"fda-depoprovera","3",[37],{"id":38,"disease":39,"label":40,"population":43,"type":44,"unit":30,"dose":45,"refs":46,"durationDays":49,"notes":50},"contra","contraception",{"fa":41,"en":42},"پیشگیری از بارداری — ۱۵۰ mg عضلانی عمیق هر ۳ ماه (۱۳ هفته)","Contraception — 150 mg deep IM every 3 months (13 weeks)",{},"fixed",{"perDose":29,"dosesPerDay":5},[47],{"source":34,"section":48},"2",{"min":5,"max":5},[51],{"text":52,"refs":55},{"fa":53,"en":54},"در عضله باسن یا دلتوئید؛ پیش از تزریق به‌شدت تکان داده شود.","Gluteal or deltoid muscle; shake vigorously before use.",[56],{"source":34,"section":57},"2.1",[59],{"id":60,"severity":61,"text":62,"refs":65},"ci","block",{"fa":63,"en":64},"ترومبوفلبیت فعال یا سابقه ترومبوآمبولی یا بیماری عروق مغز؛ سرطان پستان؛ بیماری قابل توجه کبد؛ خونریزی واژینال تشخیص‌داده‌نشده؛ حساسیت.","Active thrombophlebitis or history of thromboembolism or cerebrovascular disease; breast cancer; significant liver disease; undiagnosed vaginal bleeding; hypersensitivity.",[66],{"source":34,"section":67},"4",[69],{"text":70,"refs":73},{"fa":71,"en":72},"هشدار جعبه‌ای: کاهش تراکم استخوان؛ بیش از ۲ سال فقط اگر روش دیگری مناسب نباشد.","Boxed warning: loss of bone mineral density; use beyond 2 years only if other methods are inadequate.",[74],{"source":34,"section":75},"Boxed Warning",[],[],[],{"status":80,"reviewer":81,"date":81},"unverified",null,[83],{"regimen":38,"formulation":24,"input":84,"expect":87},{"ageYears":85,"weightKg":86},25,60,{"perDose":29,"mlPerDose":5},[89],"G03AC06",{"status":91,"forms":92,"refs":121},"registered",[93,97,101,105,109,113,117],{"code":94,"en":95,"fa":96},"00791","MEDROXYPROGESTERONE ACETATE 150MG\u002F1ML AMP","آمپول مدروکسی‌پروژسترون استات ۱۵۰ میلی‌گرم \u002F ۱ میلی‌لیتر",{"code":98,"en":99,"fa":100},"13657","MEDROXYPROGESTERONE ACETATE 150MG\u002F3ML VIAL","ویال مدروکسی‌پروژسترون استات ۱۵۰ میلی‌گرم \u002F ۳ میلی‌لیتر",{"code":102,"en":103,"fa":104},"00789","MEDROXYPROGESTERONE ACETATE 250MG TAB","قرص مدروکسی‌پروژسترون استات ۲۵۰ میلی‌گرم",{"code":106,"en":107,"fa":108},"00793","MEDROXYPROGESTERONE ACETATE 500MG\u002F2.5ML AMP","آمپول مدروکسی‌پروژسترون استات ۵۰۰ میلی‌گرم \u002F ۲٫۵ میلی‌لیتر",{"code":110,"en":111,"fa":112},"00790","MEDROXYPROGESTERONE ACETATE 500MG\u002F5ML VIAL","ویال مدروکسی‌پروژسترون استات ۵۰۰ میلی‌گرم \u002F ۵ میلی‌لیتر",{"code":114,"en":115,"fa":116},"00792","MEDROXYPROGESTERONE ACETATE 5MG TAB","قرص مدروکسی‌پروژسترون استات ۵ میلی‌گرم",{"code":118,"en":119,"fa":120},"06066","MEDROXYPROGESTRON 500MG\u002F3.3ML VIAL","ویال مدروکسیپروجسترون ۵۰۰ میلی‌گرم \u002F ۳٫۳ میلی‌لیتر",[122],{"source":123,"section":124,"url":125},"darooyab-generic","G-3275\u002FMedroxyprogesterone-Acetate","https:\u002F\u002Fwww.darooyab.ir\u002FG-3275\u002FMedroxyprogesterone-Acetate",[127,131,135,139,142],{"kind":128,"url":129,"label":130},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=020246","NDA020246",{"kind":132,"url":133,"label":134},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=199cf13e-0859-4a73-9b45-e700d0cd1049","FDA Depo-Provera CI",{"kind":136,"url":137,"label":138},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa604039.html","Medroxyprogesterone Injection",{"kind":140,"url":141,"label":89},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=G03AC06",{"kind":143,"url":125,"label":144},"darooyab","Medroxyprogesterone-Acetate",{"pregnancy":146,"lactation":155,"pediatric":163,"geriatric":171,"reproductive":179},{"level":147,"text":148,"quote":151,"refs":152},"caution",{"fa":149,"en":150},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary There is no use for contraception in pregnancy; therefore, Depo-Provera CI should be discontinued during pregnancy.",[153],{"source":34,"section":154},"8.1",{"level":147,"text":156,"quote":159,"refs":160},{"fa":157,"en":158},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary Although medroxyprogesterone acetate is detectable in the milk of mothers receiving Depo-Provera CI, milk composition, quality, and amount do not appear to be adversely affected.",[161],{"source":34,"section":162},"8.2",{"level":147,"text":164,"quote":167,"refs":168},{"fa":165,"en":166},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","Depo-Provera CI is not indicated before menarche.",[169],{"source":34,"section":170},"8.4",{"level":147,"text":172,"quote":175,"refs":176},{"fa":173,"en":174},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","This product has not been studied in post-menopausal women and is not indicated in this population.",[177],{"source":34,"section":178},"8.5",{"level":147,"text":180,"quote":183,"refs":184},{"fa":181,"en":182},"برچسب نکته‌ای درباره بارداری، پیشگیری یا باروری زنان و مردان دارد.","Label has advice on pregnancy testing, contraception or fertility for females and males.","Depo-Provera CI is indicated for the prevention of pregnancy and would therefore be expected to impair female fertility until cessation of treatment.",[185],{"source":34,"section":186},"8.3",{"kind":188,"refs":189,"id":130},"NDA",[190],{"source":34,"section":191},"SPL approval \u002F marketing category",1792091063442]