[{"data":1,"prerenderedAt":213},["ShallowReactive",2],{"drug-magnesium-sulfate":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":22,"regimens":36,"contraindications":78,"warnings":88,"renal":96,"monitoring":97,"interactions":98,"review":99,"examples":102,"atc":109,"iran":111,"links":175,"populations":190,"usApproval":208},"magnesium-sulfate",1,{"fa":7,"en":8},"سولفات منیزیم (تزریقی)","Magnesium sulfate (injection)","blood",{"fa":11,"en":12},"الکترولیت \u002F ضدتشنج اکلامپسی","Electrolyte \u002F anticonvulsant in eclampsia",[14],{"name":15,"market":16},"Magnesium sulfate 50%","US",[18,19,20,21],"magnesium sulfate","سولفات منیزیم","منیزیم سولفات","آمپول منیزیم",[23],{"id":24,"form":25,"route":26,"label":27,"concentration":28,"markets":31,"refs":32},"syr-50","injection","im","50% (500 mg\u002FmL; 4 mEq\u002FmL)",{"amount":29,"unit":30,"perVolumeMl":5},500,"mg",[16],[33],{"source":34,"section":35},"fda-magsulf","How Supplied",[37,64],{"id":38,"disease":39,"label":40,"population":43,"type":47,"unit":30,"dose":48,"refs":51,"durationDays":54,"notes":55},"mild","hypomagnesemia",{"fa":41,"en":42},"کمبود خفیف منیزیم — بزرگسال: ۱ گرم عضلانی هر ۶ ساعت (۴ دوز)","Mild magnesium deficiency — adult: 1 g IM every 6 h for 4 doses",{"minAge":44},{"value":45,"unit":46},18,"year","fixed",{"perDose":49,"dosesPerDay":50},1000,4,[52],{"source":34,"section":53},"Dosage — In Magnesium Deficiency",{"min":5,"max":5},[56],{"text":57,"refs":60},{"fa":58,"en":59},"۲ mL از محلول ۵۰٪. شدید: تا ۲۵۰ mg\u002Fkg عضلانی در ۴ ساعت، یا ۵ گرم در یک لیتر سرم طی ۳ ساعت. در کودکان پیش از عضلانی به ۲۰٪ یا کمتر رقیق شود.","2 mL of the 50% solution. Severe: up to 250 mg\u002Fkg IM within 4 h, or 5 g in 1 L over 3 h. In children dilute to ≤20% before IM.",[61,62],{"source":34,"section":53},{"source":34,"section":63},"Dosage and Administration",{"id":65,"disease":65,"label":66,"population":69,"type":70,"unit":30,"dose":71,"refs":75},"eclampsia",{"fa":67,"en":68},"پره‌اکلامپسی شدید \u002F اکلامپسی — طبق پروتکل برچسب","Severe pre-eclampsia \u002F eclampsia — per label protocol",{},"notCalculated",{"reason":72},{"fa":73,"en":74},"دوز اولیه کل ۱۰ تا ۱۴ گرم: ۴ تا ۵ گرم وریدی + تا ۱۰ گرم عضلانی (۵ گرم در هر باسن)، سپس ۴ تا ۵ گرم عضلانی هر ۴ ساعت یا ۱ تا ۲ گرم در ساعت انفوزیون؛ حداکثر ۳۰ تا ۴۰ گرم در ۲۴ ساعت. رفلکس زانو و تنفس پایش شود.","Total initial dose 10–14 g: 4–5 g IV + up to 10 g IM (5 g each buttock), then 4–5 g IM every 4 h or 1–2 g\u002Fh infusion; do not exceed 30–40 g in 24 h. Monitor patellar reflex and respiration.",[76],{"source":34,"section":77},"Dosage — In Pre-eclampsia or Eclampsia",[79],{"id":80,"severity":81,"text":82,"refs":85},"ci","block",{"fa":83,"en":84},"بلوک قلبی یا آسیب میوکارد (تزریقی).","Heart block or myocardial damage (parenteral).",[86],{"source":34,"section":87},"Contraindications",[89],{"text":90,"refs":93},{"fa":91,"en":92},"مصرف مداوم بیش از ۵ تا ۷ روز در بارداری می‌تواند هیپوکلسمی و ناهنجاری استخوانی جنین بدهد. در نارسایی کلیه با احتیاط.","Continuous use beyond 5–7 days in pregnancy can cause fetal hypocalcaemia and bone abnormalities. Use caution in renal impairment.",[94],{"source":34,"section":95},"Warnings",[],[],[],{"status":100,"reviewer":101,"date":101},"unverified",null,[103],{"regimen":38,"formulation":24,"input":104,"expect":107},{"ageYears":105,"weightKg":106},40,70,{"perDose":49,"mlPerDose":108},2,[110],"B05XA05",{"status":112,"forms":113,"refs":170},"registered",[114,118,122,126,130,134,138,142,146,150,154,158,162,166],{"code":115,"en":116,"fa":117},"02484","MAGNESIUM GLUCONATE 0.22MG TAB","قرص منیزیم گلوکونات ۰٫۲۲ میلی‌گرم",{"code":119,"en":120,"fa":121},"00776","MAGNESIUM GLUCONATE 500MG TAB","قرص منیزیم گلوکونات ۵۰۰ میلی‌گرم",{"code":123,"en":124,"fa":125},"15514","MAGNESIUM LACTATE DIHYDRATE 4MG TAB","قرص منیزیم لاکتات دی‌هیدرات ۴ میلی‌گرم",{"code":127,"en":128,"fa":129},"08272","MAGNESIUM SULFATE 10% 10ML VIAL","ویال منیزیم سولفات ۱۰ درصد ۱۰ میلی‌لیتر",{"code":131,"en":132,"fa":133},"17831","MAGNESIUM SULFATE 10% 50ML BAG","منیزیم سولفات ۱۰ درصد ۵۰ میلی‌لیتر",{"code":135,"en":136,"fa":137},"00778","MAGNESIUM SULFATE 10% 50ML VIAL","ویال منیزیم سولفات ۱۰ درصد ۵۰ میلی‌لیتر",{"code":139,"en":140,"fa":141},"01337","MAGNESIUM SULFATE 20 G POWDER","پودر منیزیم سولفات ۲۰ گرم",{"code":143,"en":144,"fa":145},"08269","MAGNESIUM SULFATE 20% 10ML VIAL","ویال منیزیم سولفات ۲۰ درصد ۱۰ میلی‌لیتر",{"code":147,"en":148,"fa":149},"17832","MAGNESIUM SULFATE 20% 50ML BAG","منیزیم سولفات ۲۰ درصد ۵۰ میلی‌لیتر",{"code":151,"en":152,"fa":153},"00779","MAGNESIUM SULFATE 20% 50ML VIAL","ویال منیزیم سولفات ۲۰ درصد ۵۰ میلی‌لیتر",{"code":155,"en":156,"fa":157},"03823","MAGNESIUM SULFATE 50% 10ML VIAL","ویال منیزیم سولفات ۵۰ درصد ۱۰ میلی‌لیتر",{"code":159,"en":160,"fa":161},"00780","MAGNESIUM SULFATE 50% 50ML VIAL","ویال منیزیم سولفات ۵۰ درصد ۵۰ میلی‌لیتر",{"code":163,"en":164,"fa":165},"51854","MAGNESIUM SULFATE INJECTION PARENTERAL 10 % 50 mL","فرآورده تزریقی منیزیم سولفات ۱۰ درصد ۵۰ میلی‌لیتر",{"code":167,"en":168,"fa":169},"22689","MAGNESIUM SULFATE INJECTION PARENTERAL 50 % 50 mL","فرآورده تزریقی منیزیم سولفات ۵۰ درصد ۵۰ میلی‌لیتر",[171],{"source":172,"section":173,"url":174},"darooyab-generic","G-2507\u002FMagnesium-Sulfate","https:\u002F\u002Fwww.darooyab.ir\u002FG-2507\u002FMagnesium-Sulfate",[176,180,184,187],{"kind":177,"url":178,"label":179},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=075151","ANDA075151",{"kind":181,"url":182,"label":183},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=d4b5863a-efb9-4551-a9ad-2b06e8666d87","FDA Mag. sulfate 50%",{"kind":185,"url":186,"label":110},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=B05XA05",{"kind":188,"url":174,"label":189},"darooyab","Magnesium-Sulfate",{"pregnancy":191,"lactation":200},{"level":192,"text":193,"quote":196,"refs":197},"caution",{"fa":194,"en":195},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","(See WARNINGS and PRECAUTIONS )",[198],{"source":34,"section":199},"Precautions\u002FWarnings – Pregnancy",{"level":192,"text":201,"quote":204,"refs":205},{"fa":202,"en":203},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Since magnesium is distributed into milk during parenteral magnesium sulfate administration, the drug should be used with caution in nursing women.",[206],{"source":34,"section":207},"Precautions\u002FWarnings – Nursing Mothers",{"kind":209,"refs":210,"id":179},"ANDA",[211],{"source":34,"section":212},"SPL approval \u002F marketing category",1792091063248]