[{"data":1,"prerenderedAt":181},["ShallowReactive",2],{"drug-labetalol":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":20,"regimens":51,"contraindications":75,"warnings":85,"renal":86,"monitoring":87,"interactions":88,"review":89,"examples":92,"atc":98,"iran":100,"links":132,"populations":149,"usApproval":176},"labetalol",1,{"fa":7,"en":8},"لابتالول","Labetalol","cardiovascular",{"fa":11,"en":12},"بتابلاکر با اثر آلفا","Alpha\u002Fbeta blocker",[14],{"name":15,"market":16},"Trandate","US",[18,7,19],"trandate","ترانديت",[21,35,43],{"id":22,"form":23,"route":24,"label":25,"concentration":26,"markets":30,"refs":31},"tab-100","tablet","oral","100 mg tablet (scored)",{"amount":27,"unit":28,"perUnit":23,"scored":29},100,"mg",true,[16],[32],{"source":33,"section":34},"fda-labetalol","How Supplied",{"id":36,"form":23,"route":24,"label":37,"concentration":38,"markets":40,"refs":41},"tab-200","200 mg tablet (scored)",{"amount":39,"unit":28,"perUnit":23,"scored":29},200,[16],[42],{"source":33,"section":34},{"id":44,"form":23,"route":24,"label":45,"concentration":46,"markets":48,"refs":49},"tab-300","300 mg tablet (scored)",{"amount":47,"unit":28,"perUnit":23,"scored":29},300,[16],[50],{"source":33,"section":34},[52],{"id":53,"disease":54,"label":55,"population":58,"type":62,"unit":28,"dose":63,"refs":65,"notes":68},"htn","hypertension",{"fa":56,"en":57},"فشار خون — شروع ۱۰۰ mg دو بار در روز","Hypertension — start 100 mg twice daily",{"minAge":59},{"value":60,"unit":61},18,"year","fixed",{"perDose":27,"dosesPerDay":64},2,[66],{"source":33,"section":67},"Dosage and Administration",[69],{"text":70,"refs":73},{"fa":71,"en":72},"هر ۲ تا ۳ روز ۱۰۰ mg دو بار افزایش؛ نگهدارنده معمول ۲۰۰ تا ۴۰۰ mg دو بار در روز.","Increase by 100 mg twice daily every 2–3 days; usual maintenance 200–400 mg twice daily.",[74],{"source":33,"section":67},[76],{"id":77,"severity":78,"text":79,"refs":82},"ci","block",{"fa":80,"en":81},"آسم؛ نارسایی آشکار قلب؛ بلوک بیش از درجه ۱؛ شوک کاردیوژنیک؛ برادی‌کاردی شدید؛ افت فشار طولانی.","Bronchial asthma; overt heart failure; greater than first-degree block; cardiogenic shock; severe bradycardia; prolonged hypotension.",[83],{"source":33,"section":84},"Contraindications",[],[],[],[],{"status":90,"reviewer":91,"date":91},"unverified",null,[93],{"regimen":53,"formulation":22,"input":94,"expect":97},{"ageYears":95,"weightKg":96},50,80,{"perDose":27,"tabletsPerDoseRounded":5},[99],"C07AG01",{"status":101,"forms":102,"refs":127},"registered",[103,107,111,115,119,123],{"code":104,"en":105,"fa":106},"09314","LABETALOL 100MG TAB","قرص لابتالول ۱۰۰ میلی‌گرم",{"code":108,"en":109,"fa":110},"09315","LABETALOL 200MG TAB","قرص لابتالول ۲۰۰ میلی‌گرم",{"code":112,"en":113,"fa":114},"09316","LABETALOL 400MG TAB","قرص لابتالول ۴۰۰ میلی‌گرم",{"code":116,"en":117,"fa":118},"08004","LABETALOL 5MG\u002FML 20ML INJ","فرآورده تزریقی لابتالول ۵ میلی‌گرم \u002F میلی‌لیتر ۲۰ میلی‌لیتر",{"code":120,"en":121,"fa":122},"52006","LABETALOL HYDROCHLORIDE INJECTION PARENTERAL 5 mg\u002F1mL 4 mL","فرآورده تزریقی لابتالول هیدروکلراید ۵ میلی‌گرم \u002F ۱ میلی‌لیتر ۴ میلی‌لیتر",{"code":124,"en":125,"fa":126},"52258","LABETALOL HYDROCHLORIDE INJECTION PARENTERAL 5 mg\u002F1mL 10 mL","فرآورده تزریقی لابتالول هیدروکلراید ۵ میلی‌گرم \u002F ۱ میلی‌لیتر ۱۰ میلی‌لیتر",[128],{"source":129,"section":130,"url":131},"darooyab-generic","G-1725\u002FLabetalol","https:\u002F\u002Fwww.darooyab.ir\u002FG-1725\u002FLabetalol",[133,137,141,144,147],{"kind":134,"url":135,"label":136},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=207743","ANDA207743",{"kind":138,"url":139,"label":140},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=63ede355-42ec-4c52-a941-51e5f6b35ed6","FDA Labetalol",{"kind":142,"url":143,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa685034.html",{"kind":145,"url":146,"label":99},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=C07AG01",{"kind":148,"url":131,"label":8},"darooyab",{"pregnancy":150,"lactation":159,"pediatric":167},{"level":151,"text":152,"quote":155,"refs":156},"caution",{"fa":153,"en":154},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Teratogenic Effects Pregnancy Category C Teratogenic studies were performed with labetalol in rats and rabbits at oral doses up to approximately six and four times the maximum recommended human dose (MRHD), respectively.",[157],{"source":33,"section":158},"Pregnancy",{"level":151,"text":160,"quote":163,"refs":164},{"fa":161,"en":162},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Caution should be exercised when labetalol hydrochloride is administered to a nursing woman..",[165],{"source":33,"section":166},"Nursing Mothers",{"level":168,"text":169,"quote":172,"refs":173},"not-established",{"fa":170,"en":171},"برچسب: ایمنی و اثربخشی در کودکان ثابت نشده است.","Label: safety and effectiveness in children have not been established.","Safety and effectiveness in pediatric patients have not been established.",[174],{"source":33,"section":175},"Pediatric Use",{"kind":177,"refs":178,"id":136},"ANDA",[179],{"source":33,"section":180},"SPL approval \u002F marketing category",1792092037200]