[{"data":1,"prerenderedAt":277},["ShallowReactive",2],{"drug-ivig":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":22,"regimens":36,"contraindications":87,"warnings":97,"renal":112,"monitoring":113,"interactions":114,"review":115,"examples":118,"atc":133,"iran":135,"usApproval":223,"links":229,"populations":243},"ivig",1,{"fa":7,"en":8},"ایمونوگلوبولین وریدی (IVIG)","Immune globulin intravenous (IVIG) 10%","anti-infectives",{"fa":11,"en":12},"ایمونوگلوبولین انسانی","Human immune globulin",[14],{"name":15,"market":16},"Gammagard Liquid","US",[4,18,19,20,21],"immune globulin","ایمونوگلوبولین","آی وی آی جی","gammagard",[23],{"id":24,"form":25,"route":26,"label":27,"concentration":28,"markets":31,"refs":32},"sol-10","injection","iv","10% (100 mg\u002FmL)",{"amount":29,"unit":30,"perVolumeMl":5},100,"mg",[16],[33],{"source":34,"section":35},"fda-gammagard","3",[37,63],{"id":38,"disease":39,"label":40,"population":43,"type":47,"unit":30,"dose":48,"refs":52,"durationDays":55,"notes":56},"pi","primary-immunodeficiency",{"fa":41,"en":42},"نقص ایمنی اولیه — ۳۰۰ تا ۶۰۰ mg\u002Fkg وریدی هر ۳ تا ۴ هفته","Primary immunodeficiency — 300–600 mg\u002Fkg IV every 3–4 weeks",{"minAge":44},{"value":45,"unit":46},2,"year","weightBased",{"perKgPerDose":49,"perKgPerDoseMax":50,"intervalHours":51},300,600,24,[53],{"source":34,"section":54},"2.1, Table 1",{"min":5,"max":5},[57],{"text":58,"refs":61},{"fa":59,"en":60},"شروع ۰٫۵ mL\u002Fkg\u002Fساعت ۳۰ دقیقه، سپس هر ۳۰ دقیقه افزایش تا ۵ mL\u002Fkg\u002Fساعت. تنظیم با سطح IgG.","Start 0.5 mL\u002Fkg\u002Fh for 30 min, then increase every 30 min up to 5 mL\u002Fkg\u002Fh. Adjust to IgG levels.",[62],{"source":34,"section":54},{"id":64,"disease":64,"label":65,"population":68,"type":47,"unit":30,"dose":71,"refs":73,"durationDays":76,"notes":77},"cidp",{"fa":66,"en":67},"CIDP بزرگسال — القا ۲ g\u002Fkg تقسیم طی ۲ تا ۵ روز؛ نگهدارنده ۱ g\u002Fkg هر ۳ هفته","CIDP, adults — induction 2 g\u002Fkg divided over 2–5 days; maintenance 1 g\u002Fkg every 3 weeks",{"minAge":69},{"value":70,"unit":46},18,{"perKgPerDose":72,"intervalHours":51},2000,[74],{"source":34,"section":75},"2.3, Table 5",{"min":5,"max":5},[78],{"text":79,"refs":82},{"fa":80,"en":81},"عدد ماشین‌حساب کل دوز القا است (تقسیم طی ۲ تا ۵ روز). نوروپاتی حرکتی چندکانونی: ۰٫۵ تا ۲٫۴ g\u002Fkg\u002Fماه.","The calculator gives the total induction dose (divide over 2–5 days). Multifocal motor neuropathy: 0.5–2.4 g\u002Fkg\u002Fmonth.",[83,85],{"source":34,"section":84},"2.3",{"source":34,"section":86},"2.2",[88],{"id":89,"severity":90,"text":91,"refs":94},"ci","block",{"fa":92,"en":93},"آنافیلاکسی یا حساسیت شدید به ایمونوگلوبولین انسانی؛ کمبود IgA با آنتی‌بادی ضد IgA و سابقه حساسیت.","Anaphylaxis or severe hypersensitivity to human immune globulin; IgA deficiency with anti-IgA antibodies and history of hypersensitivity.",[95],{"source":34,"section":96},"4",[98,105],{"text":99,"refs":102},{"fa":100,"en":101},"هشدار جعبه‌ای: ترومبوز؛ اختلال و نارسایی حاد کلیه — کمترین غلظت و سرعت در بیماران پرخطر، هیدراتاسیون کافی.","Boxed warning: thrombosis; renal dysfunction and acute renal failure — use minimum concentration and rate in at-risk patients, ensure hydration.",[103],{"source":34,"section":104},"Boxed Warning",{"text":106,"refs":109},{"fa":107,"en":108},"مننژیت آسپتیک؛ همولیز؛ TRALI؛ افزایش ویسکوزیته.","Aseptic meningitis; haemolysis; TRALI; hyperviscosity.",[110],{"source":34,"section":111},"5",[],[],[],{"status":116,"reviewer":117,"date":117},"unverified",null,[119,127],{"regimen":38,"formulation":24,"input":120,"expect":123},{"ageYears":121,"weightKg":122},30,70,{"perDose":124,"mlPerDose":125,"upperPerDose":126},21000,210,42000,{"regimen":64,"formulation":24,"input":128,"expect":130},{"ageYears":129,"weightKg":122},50,{"perDose":131,"mlPerDose":132},140000,1400,[134],"J06BA02",{"status":136,"forms":137,"refs":218},"registered",[138,142,146,150,154,158,162,166,170,174,178,182,186,190,194,198,202,206,210,214],{"code":139,"en":140,"fa":141},"15813","IMMUNE GLOBULIN (I.V) 9G\u002F150ML VIAL","ویال ایمونوگلوبولین (ای.و) ۹ گرم \u002F ۱۵۰ میلی‌لیتر",{"code":143,"en":144,"fa":145},"01763","IMMUNE GLOBULIN 10 G (IV )VIAL","ویال ایمونوگلوبولین ۱۰ گرم (وریدی)",{"code":147,"en":148,"fa":149},"17772","IMMUNE GLOBULIN 10G\u002F100ML VIAL","ویال ایمونوگلوبولین ۱۰ گرم \u002F ۱۰۰ میلی‌لیتر",{"code":151,"en":152,"fa":153},"11694","IMMUNE GLOBULIN 12G VIAL","ویال ایمونوگلوبولین ۱۲ گرم",{"code":155,"en":156,"fa":157},"00919","IMMUNE GLOBULIN 1G (IV ) VIAL","ویال ایمونوگلوبولین ۱ گرم (وریدی)",{"code":159,"en":160,"fa":161},"00918","IMMUNE GLOBULIN 2.5 G INJECTION POWDER (IV) VIAL","پودر تزریقی ایمونوگلوبولین ۲٫۵ گرم (وریدی)",{"code":163,"en":164,"fa":165},"17770","IMMUNE GLOBULIN 2.5G\u002F25ML VIAL","ویال ایمونوگلوبولین ۲٫۵ گرم \u002F ۲۵ میلی‌لیتر",{"code":167,"en":168,"fa":169},"05843","IMMUNE GLOBULIN 2.5G\u002F50ML (IV) VIAL","ویال ایمونوگلوبولین ۲٫۵ گرم \u002F ۵۰ میلی‌لیتر (وریدی)",{"code":171,"en":172,"fa":173},"13516","IMMUNE GLOBULIN 20G\u002F200ML VIAL","ویال ایمونوگلوبولین ۲۰ گرم \u002F ۲۰۰ میلی‌لیتر",{"code":175,"en":176,"fa":177},"00920","IMMUNE GLOBULIN 3G VIAL","ویال ایمونوگلوبولین ۳ گرم",{"code":179,"en":180,"fa":181},"00878","IMMUNE GLOBULIN 5G INJECTION POWDER (IV) VIAL","پودر تزریقی ایمونوگلوبولین ۵ گرم (وریدی)",{"code":183,"en":184,"fa":185},"05842","IMMUNE GLOBULIN 5G\u002F100ML VIAL","ویال ایمونوگلوبولین ۵ گرم \u002F ۱۰۰ میلی‌لیتر",{"code":187,"en":188,"fa":189},"17773","IMMUNE GLOBULIN 5G\u002F50ML VIAL","ویال ایمونوگلوبولین ۵ گرم \u002F ۵۰ میلی‌لیتر",{"code":191,"en":192,"fa":193},"00879","IMMUNE GLOBULIN 6G (IV ) VIAL","ویال ایمونوگلوبولین ۶ گرم (وریدی)",{"code":195,"en":196,"fa":197},"50894","IMMUNE GLOBULIN INJECTION INTRAVENOUS 50 mg\u002F1mL 20 mL","فرآورده تزریقی ایمونوگلوبولین ۵۰ میلی‌گرم \u002F ۱ میلی‌لیتر ۲۰ میلی‌لیتر",{"code":199,"en":200,"fa":201},"50893","IMMUNE GLOBULIN INJECTION INTRAVENOUS 50 mg\u002F1mL 200 mL","فرآورده تزریقی ایمونوگلوبولین ۵۰ میلی‌گرم \u002F ۱ میلی‌لیتر ۲۰۰ میلی‌لیتر",{"code":203,"en":204,"fa":205},"50081","IMMUNE GLOBULIN INJECTION PARENTERAL 200 mg\u002F1mL 5 mL","فرآورده تزریقی ایمونوگلوبولین ۲۰۰ میلی‌گرم \u002F ۱ میلی‌لیتر ۵ میلی‌لیتر",{"code":207,"en":208,"fa":209},"50082","IMMUNE GLOBULIN INJECTION PARENTERAL 200 mg\u002F1mL 10 mL","فرآورده تزریقی ایمونوگلوبولین ۲۰۰ میلی‌گرم \u002F ۱ میلی‌لیتر ۱۰ میلی‌لیتر",{"code":211,"en":212,"fa":213},"50083","IMMUNE GLOBULIN INJECTION PARENTERAL 200 mg\u002F1mL 20 mL","فرآورده تزریقی ایمونوگلوبولین ۲۰۰ میلی‌گرم \u002F ۱ میلی‌لیتر ۲۰ میلی‌لیتر",{"code":215,"en":216,"fa":217},"52194","IMMUNE GLOBULIN INJECTION INTRAVENOUS 50 mg\u002F1mL 10 mL","فرآورده تزریقی ایمونوگلوبولین ۵۰ میلی‌گرم \u002F ۱ میلی‌لیتر ۱۰ میلی‌لیتر",[219],{"source":220,"section":221,"url":222},"darooyab-generic","G-4557\u002FImmune-Globulin-Intravenous","https:\u002F\u002Fwww.darooyab.ir\u002FG-4557\u002FImmune-Globulin-Intravenous",{"kind":224,"refs":225,"id":228},"BLA",[226],{"source":34,"section":227},"SPL approval \u002F marketing category","BLA125105",[230,233,237,240],{"kind":231,"url":232,"label":228},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=125105",{"kind":234,"url":235,"label":236},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=9d42adca-0dd7-4df7-864d-5a7feee52130","FDA Gammagard Liquid",{"kind":238,"url":239,"label":134},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=J06BA02",{"kind":241,"url":222,"label":242},"darooyab","Immune-Globulin-Intravenous",{"pregnancy":244,"lactation":253,"pediatric":261,"geriatric":269},{"level":245,"text":246,"quote":249,"refs":250},"caution",{"fa":247,"en":248},"برچسب: مطالعه حیوانی نشده و خطر جنینی نامعلوم است؛ فقط در صورت نیاز واضح.","Label: no animal studies and fetal risk unknown; give only if clearly needed.","It is not known whether GAMMAGARD LIQUID can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Immune globulins cross the placenta from maternal circulation increasingly after 30 weeks of gestation. GAMMAGARD LIQUID should be given to a pregnant woman only if clearly indicated.",[251],{"source":34,"section":252},"8.1",{"level":245,"text":254,"quote":257,"refs":258},{"fa":255,"en":256},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary There is no information regarding the presence of GAMMAGARD LIQUID in human milk, its effects on the breastfed infant or its effects on milk production.",[259],{"source":34,"section":260},"8.2",{"level":245,"text":262,"quote":265,"refs":266},{"fa":263,"en":264},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","Safety and efficacy of GAMMAGARD LIQUID in pediatric patients below the age of 2 have not been established.",[267],{"source":34,"section":268},"8.4",{"level":245,"text":270,"quote":273,"refs":274},{"fa":271,"en":272},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Infuse at the minimum intravenous infusion rate practicable [see Boxed Warning , Warnings and Precautions (5.2 , 5.4) and Dosage and Administration (2.5) ] .",[275],{"source":34,"section":276},"8.5",1792444403740]