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previous isoniazid liver injury; acute liver disease.",[93],{"source":33,"section":94},"Contraindications",[96],{"text":97,"refs":100},{"fa":98,"en":99},"هشدار جعبه‌ای: هپاتیت شدید و گاهی کشنده؛ خطر با افزایش سن و مصرف روزانه الکل بیشتر می‌شود؛ علائم و آنزیم کبد پایش شود.","Boxed warning: severe, sometimes fatal hepatitis; risk rises with age and daily alcohol use; monitor symptoms and liver enzymes.",[101],{"source":33,"section":102},"Boxed Warning",[],[],[],{"status":107,"reviewer":108,"date":108},"unverified",null,[110,115],{"regimen":45,"formulation":36,"input":111,"expect":114},{"ageYears":112,"weightKg":113},40,60,{"perDose":39,"tabletsPerDoseRounded":5},{"regimen":71,"formulation":22,"input":116,"expect":119},{"ageYears":117,"weightKg":118},6,20,{"perDose":120,"tabletsPerDoseRounded":121},200,2,[123],"J04AC01",{"status":125,"forms":126,"refs":139},"registered",[127,131,135],{"code":128,"en":129,"fa":130},"00712","ISONIAZID 100MG TAB","قرص ایزونیازید ۱۰۰ میلی‌گرم",{"code":132,"en":133,"fa":134},"00713","ISONIAZID 300MG TAB","قرص ایزونیازید ۳۰۰ میلی‌گرم",{"code":136,"en":137,"fa":138},"00714","ISONIAZID 500MG\u002F5ML AMP","آمپول ایزونیازید ۵۰۰ میلی‌گرم \u002F ۵ میلی‌لیتر",[140],{"source":141,"section":142,"url":143},"darooyab-generic","G-416\u002FIsoniazid","https:\u002F\u002Fwww.darooyab.ir\u002FG-416\u002FIsoniazid",[145,149,153,156,159],{"kind":146,"url":147,"label":148},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=040090","ANDA040090",{"kind":150,"url":151,"label":152},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=312cd403-b211-64ef-e063-6394a90aab88","FDA Isoniazid",{"kind":154,"url":155,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa682401.html",{"kind":157,"url":158,"label":123},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=J04AC01",{"kind":160,"url":143,"label":8},"darooyab",{"pregnancy":162,"lactation":171},{"level":163,"text":164,"quote":167,"refs":168},"caution",{"fa":165,"en":166},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Teratogenic Effects Pregnancy Category C Isoniazid has been shown to have an embryocidal effect in rats and rabbits when given orally during pregnancy.",[169],{"source":33,"section":170},"Pregnancy",{"level":163,"text":172,"quote":175,"refs":176},{"fa":173,"en":174},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","The small concentrations of isoniazid in breast milk do not produce toxicity in the nursing newborn; therefore, breast feeding should not be discouraged.",[177],{"source":33,"section":178},"Nursing Mothers",{"kind":180,"refs":181,"id":148},"ANDA",[182],{"source":33,"section":183},"SPL approval \u002F marketing category",1792092036528]