[{"data":1,"prerenderedAt":142},["ShallowReactive",2],{"drug-iron-dextran":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":22,"regimens":36,"contraindications":59,"warnings":69,"renal":84,"monitoring":85,"interactions":86,"review":87,"examples":90,"atc":91,"iran":93,"links":100,"populations":119,"usApproval":137},"iron-dextran",1,{"fa":7,"en":8},"آیرون دکستران","Iron dextran","blood",{"fa":11,"en":12},"آهن تزریقی","Parenteral iron",[14],{"name":15,"market":16},"INFeD","US",[18,19,20,7,21],"infed","cosmofer","کاسموفر","آهن دکستران",[23],{"id":24,"form":25,"route":26,"label":27,"concentration":28,"markets":31,"refs":32},"inj-50","injection","iv","50 mg\u002FmL, 2 mL vial (IV or IM)",{"amount":29,"unit":30,"perVolumeMl":5},50,"mg",[16],[33],{"source":34,"section":35},"fda-infed","3",[37],{"id":38,"disease":39,"label":40,"population":43,"type":47,"unit":30,"dose":48,"refs":52},"ida","iron-deficiency-anemia",{"fa":41,"en":42},"فقر آهن وقتی آهن خوراکی ممکن نیست — دوز کل از جدول یا فرمول برچسب (هموگلوبین و وزن)","Iron deficiency when oral iron is not possible — total dose from the label table or formula (haemoglobin and weight)",{"minAge":44},{"value":45,"unit":46},4,"month","notCalculated",{"reason":49},{"fa":50,"en":51},"بزرگسال و کودک بالای ۱۵ kg: حجم (mL) = ۰٫۰۴۴۲ × (Hb هدف − Hb فعلی) × وزن بدون چربی + ۰٫۲۶ × وزن بدون چربی (هدف ۱۴٫۸). ۵ تا ۱۵ kg: با وزن واقعی و هدف ۱۲. ابتدا دوز آزمایشی ۰٫۵ mL و ۱ ساعت صبر؛ حداکثر روزانه ۲ mL (۱۰۰ mg)؛ سرعت حداکثر ۵۰ mg\u002Fدقیقه.","Adults and children >15 kg: volume (mL) = 0.0442 × (target Hb − observed Hb) × lean body weight + 0.26 × LBW (target 14.8). 5–15 kg: actual weight and target 12. Give a 0.5 mL test dose first and wait 1 h; max daily 2 mL (100 mg); rate max 50 mg\u002Fmin.",[53,55,57],{"source":34,"section":54},"2.2",{"source":34,"section":56},"2.4",{"source":34,"section":58},"2.1",[60],{"id":61,"severity":62,"text":63,"refs":66},"hyper","block",{"fa":64,"en":65},"سابقه حساسیت به آیرون دکستران.","Previous hypersensitivity to iron dextran.",[67],{"source":34,"section":68},"4",[70,77],{"text":71,"refs":74},{"fa":72,"en":73},"هشدار جعبه‌ای: واکنش‌های آنافیلاکتیک کشنده — دوز آزمایشی پیش از اولین دوز درمانی و امکانات احیا در دسترس.","Boxed warning: fatal anaphylactic-type reactions — test dose before the first therapeutic dose, resuscitation equipment at hand.",[75],{"source":34,"section":76},"Boxed Warning",{"text":78,"refs":81},{"fa":79,"en":80},"واکنش تأخیری (آرترالژی، میالژی، تب) ۱ تا ۲ روز بعد؛ اضافه بار آهن.","Delayed reactions (arthralgia, myalgia, fever) 1–2 days later; iron overload.",[82],{"source":34,"section":83},"5",[],[],[],{"status":88,"reviewer":89,"date":89},"unverified",null,[],[92],"B03AC",{"status":94,"refs":95},"not-found",[96],{"source":97,"section":98,"url":99},"darooyab-generic","G-2895\u002FIron-Dextran","https:\u002F\u002Fwww.darooyab.ir\u002FG-2895\u002FIron-Dextran",[101,105,109,113,116],{"kind":102,"url":103,"label":104},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=017441","NDA017441",{"kind":106,"url":107,"label":108},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=94b01b1e-794b-4bea-8e24-2e54683fc023","FDA INFeD",{"kind":110,"url":111,"label":112},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa614033.html","Iron Dextran Injection",{"kind":114,"url":115,"label":92},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=B03AC",{"kind":117,"url":99,"label":118},"darooyab","Iron-Dextran",{"pregnancy":120,"pediatric":129},{"level":121,"text":122,"quote":125,"refs":126},"caution",{"fa":123,"en":124},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary Parenteral iron administration may be associated with hypersensitivity reactions [see Warnings and Precautions ( 5.1 )] , which may have serious consequences, such as fetal bradycardia (see Clinical Considerations).",[127],{"source":34,"section":128},"8.1",{"level":121,"text":130,"quote":133,"refs":134},{"fa":131,"en":132},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","INFeD is not recommended for use in infants under 4 months of age [s ee Dosage and Administration ( 2.2 ) ].",[135],{"source":34,"section":136},"8.4",{"kind":138,"refs":139,"id":104},"NDA",[140],{"source":34,"section":141},"SPL approval \u002F marketing category",1792444404827]