[{"data":1,"prerenderedAt":230},["ShallowReactive",2],{"drug-heparin":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":19,"regimens":33,"contraindications":79,"warnings":89,"renal":97,"monitoring":98,"interactions":99,"review":100,"examples":103,"atc":116,"iran":118,"links":178,"populations":192,"usApproval":225},"heparin",1,{"fa":7,"en":8},"هپارین","Heparin","blood",{"fa":11,"en":12},"ضدانعقاد","Anticoagulant",[14],{"name":15,"market":16},"Heparin sodium","US",[4,7,18],"آمپول هپارین",[20],{"id":21,"form":22,"route":23,"label":24,"concentration":25,"markets":28,"refs":29},"vial-5000","injection","sc","5,000 USP units\u002FmL vial",{"amount":26,"unit":27,"perVolumeMl":5},5000,"unit",[16],[30],{"source":31,"section":32},"fda-heparin","3",[34,57],{"id":35,"disease":36,"label":37,"population":40,"type":44,"unit":27,"dose":45,"refs":47,"notes":50},"proph","dvt-prophylaxis",{"fa":38,"en":39},"پیشگیری ترومبوز پس از جراحی — ۵۰۰۰ واحد زیرجلدی هر ۸ تا ۱۲ ساعت","Post-operative prophylaxis — 5,000 units SC every 8–12 h",{"minAge":41},{"value":42,"unit":43},18,"year","fixed",{"perDose":26,"dosesPerDay":46},2,[48],{"source":31,"section":49},"2.7",[51],{"text":52,"refs":55},{"fa":53,"en":54},"اولین دوز ۲ ساعت پیش از جراحی؛ ۷ روز یا تا راه افتادن کامل.","First dose 2 h before surgery; 7 days or until fully ambulatory.",[56],{"source":31,"section":49},{"id":58,"disease":59,"label":60,"population":63,"type":65,"unit":27,"dose":66,"refs":69,"notes":72},"child","venous-thromboembolism",{"fa":61,"en":62},"کودکان — دوز اولیه ۷۵ تا ۱۰۰ واحد\u002Fkg وریدی بولوس","Children — initial 75–100 units\u002Fkg IV bolus",{"maxAge":64},{"value":42,"unit":43},"weightBased",{"perKgPerDay":67,"perKgPerDayMax":68,"dividedDoses":5},75,100,[70],{"source":31,"section":71},"2.5",[73],{"text":74,"refs":77},{"fa":75,"en":76},"سپس انفوزیون بر اساس aPTT. در نوزاد و شیرخوار فقط فرآورده بدون بنزیل الکل.","Then infusion adjusted to aPTT. In neonates and infants use preservative-free heparin only.",[78],{"source":31,"section":71},[80],{"id":81,"severity":82,"text":83,"refs":86},"ci","block",{"fa":84,"en":85},"سابقه HIT؛ حساسیت به هپارین یا فرآورده خوکی؛ وقتی پایش انعقادی ممکن نیست (دوز کامل)؛ خونریزی کنترل‌نشده.","History of HIT; hypersensitivity to heparin or pork products; full-dose use where coagulation tests cannot be done; uncontrolled bleeding.",[87],{"source":31,"section":88},"4",[90],{"text":91,"refs":94},{"fa":92,"en":93},"اشتباه مرگبار با ویال‌های «فلاش کاتتر» یا قدرت دیگر — برچسب ویال دوباره چک شود.","Fatal errors from confusing with catheter lock-flush vials or other strengths — check the vial label.",[95],{"source":31,"section":96},"2.1",[],[],[],{"status":101,"reviewer":102,"date":102},"unverified",null,[104,109],{"regimen":35,"formulation":21,"input":105,"expect":108},{"ageYears":106,"weightKg":107},50,70,{"perDose":26,"mlPerDose":5},{"regimen":58,"formulation":21,"input":110,"expect":113},{"ageYears":111,"weightKg":112},6,20,{"perDose":114,"mlPerDose":115},1500,0.3,[117],"B01AB01",{"status":119,"forms":120,"refs":173},"registered",[121,125,129,133,137,141,145,149,153,157,161,165,169],{"code":122,"en":123,"fa":124},"00625","HEPARIN SODIUM 10,000U\u002F1ML AMP","آمپول هپارین سدیم ۱۰ ۰۰۰ واحد \u002F ۱ میلی‌لیتر",{"code":126,"en":127,"fa":128},"01529","HEPARIN SODIUM 1000 IU\u002FML AMP","آمپول هپارین سدیم ۱۰۰۰ واحد بین‌المللی \u002F میلی‌لیتر",{"code":130,"en":131,"fa":132},"13044","HEPARIN SODIUM 10000IU\u002FML 10ML  AMP","آمپول هپارین سدیم ۱۰۰۰۰ واحد بین‌المللی \u002F میلی‌لیتر ۱۰ میلی‌لیتر",{"code":134,"en":135,"fa":136},"01977","HEPARIN SODIUM 2,500U\u002FML VIAL","ویال هپارین سدیم ۲ ۵۰۰ واحد \u002F میلی‌لیتر",{"code":138,"en":139,"fa":140},"01978","HEPARIN SODIUM 25,000U\u002F5ML VIAL","ویال هپارین سدیم ۲۵ ۰۰۰ واحد \u002F ۵ میلی‌لیتر",{"code":142,"en":143,"fa":144},"00626","HEPARIN SODIUM 25,000U\u002FML AMP","آمپول هپارین سدیم ۲۵ ۰۰۰ واحد \u002F میلی‌لیتر",{"code":146,"en":147,"fa":148},"00624","HEPARIN SODIUM 5,000U\u002F1ML AMP","آمپول هپارین سدیم ۵ ۰۰۰ واحد \u002F ۱ میلی‌لیتر",{"code":150,"en":151,"fa":152},"13038","HEPARIN SODIUM 5,000U\u002F1ML PRE FILLED SYRINGE","سرنگ از پیش پرشده هپارین سدیم ۵ ۰۰۰ واحد \u002F ۱ میلی‌لیتر",{"code":154,"en":155,"fa":156},"13454","HEPARIN SODIUM 5000IU\u002F5ML INJ","فرآورده تزریقی هپارین سدیم ۵۰۰۰ واحد بین‌المللی \u002F ۵ میلی‌لیتر",{"code":158,"en":159,"fa":160},"10313","HEPARIN SODIUM 60,000U 100GR AMP","آمپول هپارین سدیم ۶۰ ۰۰۰ واحد ۱۰۰ گرم",{"code":162,"en":163,"fa":164},"51851","HEPARIN SODIUM INJECTION PARENTERAL 5000 [iU]\u002F1mL 5 mL","فرآورده تزریقی هپارین سدیم ۵۰۰۰ واحد بین‌المللی \u002F ۱ میلی‌لیتر ۵ میلی‌لیتر",{"code":166,"en":167,"fa":168},"52530","HEPARIN SODIUM INJECTION PARENTERAL 1000 [iU]\u002F1mL 1 mL","فرآورده تزریقی هپارین سدیم ۱۰۰۰ واحد بین‌المللی \u002F ۱ میلی‌لیتر ۱ میلی‌لیتر",{"code":170,"en":171,"fa":172},"52780","HEPARIN SODIUM INJECTION PARENTERAL 1000 [iU]\u002F1mL 2 mL","فرآورده تزریقی هپارین سدیم ۱۰۰۰ واحد بین‌المللی \u002F ۱ میلی‌لیتر ۲ میلی‌لیتر",[174],{"source":175,"section":176,"url":177},"darooyab-generic","G-1701\u002FHeparin","https:\u002F\u002Fwww.darooyab.ir\u002FG-1701\u002FHeparin",[179,183,187,190],{"kind":180,"url":181,"label":182},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=205323","ANDA205323",{"kind":184,"url":185,"label":186},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=301b19bc-21c2-4a35-9d29-569b08d855c4","FDA Heparin inj.",{"kind":188,"url":189,"label":117},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=B01AB01",{"kind":191,"url":177,"label":8},"darooyab",{"pregnancy":193,"lactation":202,"pediatric":210,"geriatric":217},{"level":194,"text":195,"quote":198,"refs":199},"caution",{"fa":196,"en":197},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary There are no available data on heparin sodium injection use in pregnant women to inform a drug-associated risk of major birth defects and miscarriage.",[200],{"source":31,"section":201},"8.1",{"level":194,"text":203,"quote":206,"refs":207},{"fa":204,"en":205},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary If available, preservative-free heparin sodium injection is recommended when heparin therapy is needed during lactation.",[208],{"source":31,"section":209},"8.2",{"level":194,"text":211,"quote":214,"refs":215},{"fa":212,"en":213},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","Do not use benzyl alcohol-preserved drugs in neonates and infants.",[216],{"source":31,"section":71},{"level":194,"text":218,"quote":221,"refs":222},{"fa":219,"en":220},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","… gher incidence of bleeding has been reported in patients, particularly women, over 60 years of age [see Warnings and Precautions (5.2) ] .",[223],{"source":31,"section":224},"8.5",{"kind":226,"refs":227,"id":182},"ANDA",[228],{"source":31,"section":229},"SPL approval \u002F marketing category",1792092035309]