[{"data":1,"prerenderedAt":196},["ShallowReactive",2],{"drug-gabapentin":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":21,"regimens":80,"contraindications":152,"warnings":172,"renal":173,"monitoring":174,"interactions":175,"review":176,"examples":179},"gabapentin",1,{"fa":7,"en":8},"گاباپنتین","Gabapentin","neurology",{"fa":11,"en":12},"ضدتشنج \u002F ضددرد نوروپاتیک","Anticonvulsant \u002F neuropathic pain",[14],{"name":15,"market":16},"Neurontin","US",[18,19,7,20],"neurontin","نورونتین","گاباپنتین ۳۰۰",[22,36,44,52,62,70],{"id":23,"form":24,"route":25,"label":26,"concentration":27,"markets":31,"refs":32},"cap-100","capsule","oral","100 mg capsule",{"amount":28,"unit":29,"perUnit":24,"scored":30},100,"mg",false,[16],[33],{"source":34,"section":35},"fda-neurontin","3",{"id":37,"form":24,"route":25,"label":38,"concentration":39,"markets":41,"refs":42},"cap-300","300 mg capsule",{"amount":40,"unit":29,"perUnit":24,"scored":30},300,[16],[43],{"source":34,"section":35},{"id":45,"form":24,"route":25,"label":46,"concentration":47,"markets":49,"refs":50},"cap-400","400 mg capsule",{"amount":48,"unit":29,"perUnit":24,"scored":30},400,[16],[51],{"source":34,"section":35},{"id":53,"form":54,"route":25,"label":55,"concentration":56,"markets":59,"refs":60},"tab-600","tablet","600 mg tablet (scored)",{"amount":57,"unit":29,"perUnit":54,"scored":58},600,true,[16],[61],{"source":34,"section":35},{"id":63,"form":54,"route":25,"label":64,"concentration":65,"markets":67,"refs":68},"tab-800","800 mg tablet (scored)",{"amount":66,"unit":29,"perUnit":54,"scored":58},800,[16],[69],{"source":34,"section":35},{"id":71,"form":72,"route":25,"label":73,"concentration":74,"markets":77,"refs":78},"sol-250","solution","250 mg\u002F5 mL oral solution",{"amount":75,"unit":29,"perVolumeMl":76},250,5,[16],[79],{"source":34,"section":35},[81,108,131],{"id":82,"disease":83,"label":84,"population":87,"type":91,"unit":29,"dose":92,"refs":97,"notes":101},"phn","neuropathic-pain",{"fa":85,"en":86},"درد پس از زونا — بزرگسال: روز ۱: ۳۰۰، روز ۲: ۶۰۰، روز ۳: ۹۰۰ mg\u002Fday","Postherpetic neuralgia — adults: day 1 300, day 2 600, day 3 900 mg\u002Fday",{"minAge":88},{"value":89,"unit":90},18,"year","titration",{"dividedDoses":93,"titration":94},3,{"start":95,"increment":40,"incrementEveryDays":5,"targetMin":96,"targetMax":96,"max":96},900,1800,[98],{"source":99,"section":100},"fda-gabapentin","2.1",[102],{"text":103,"refs":106},{"fa":104,"en":105},"روز ۱: ۳۰۰ mg تک‌دوز؛ روز ۲: ۳۰۰ دو بار؛ روز ۳: ۳۰۰ سه بار؛ سپس تا ۱۸۰۰ mg\u002Fday (۶۰۰ سه بار). بالای ۱۸۰۰ سود اضافه نشان نداده. دوز نمایش‌داده‌شده از روز ۳ است.","Day 1: 300 mg once; day 2: 300 twice; day 3: 300 three times; then up to 1,800 mg\u002Fday (600 tid). No added benefit shown above 1,800. Displayed dose is from day 3.",[107],{"source":99,"section":100},{"id":109,"disease":110,"label":111,"population":114,"type":117,"unit":29,"dose":118,"refs":119,"notes":122},"epi-12","epilepsy",{"fa":112,"en":113},"صرع پارشیل — ۱۲ سال به بالا: ۳۰۰ mg سه بار در روز","Partial seizures — ≥12 y: 300 mg three times daily",{"minAge":115},{"value":116,"unit":90},12,"fixed",{"perDose":40,"perDoseMax":57,"dosesPerDay":93},[120],{"source":99,"section":121},"2.2",[123],{"text":124,"refs":127},{"fa":125,"en":126},"نگهدارنده ۳۰۰ تا ۶۰۰ mg سه بار؛ تا ۲۴۰۰ mg\u002Fday در مطالعات طولانی. فاصله دوزها بیش از ۱۲ ساعت نشود. نارسایی کلیه: کاهش دوز (جدول ۱).","Maintenance 300–600 mg tid; up to 2,400 mg\u002Fday in long-term studies. Interval between doses ≤12 h. Renal impairment: reduce (Table 1).",[128,129],{"source":99,"section":121},{"source":99,"section":130},"2.3",{"id":132,"disease":110,"label":133,"population":136,"type":139,"unit":29,"dose":140,"refs":143,"notes":145},"epi-3-11",{"fa":134,"en":135},"صرع پارشیل — ۳ تا ۱۱ سال: شروع ۱۰ تا ۱۵ mg\u002Fkg\u002Fday در ۳ نوبت","Partial seizures — 3–11 y: start 10–15 mg\u002Fkg\u002Fday in 3 doses",{"minAge":137,"maxAge":138},{"value":93,"unit":90},{"value":116,"unit":90},"weightBased",{"perKgPerDay":141,"perKgPerDayMax":142,"dividedDoses":93},10,15,[144],{"source":99,"section":121},[146],{"text":147,"refs":150},{"fa":148,"en":149},"طی حدود ۳ روز به نگهدارنده: ۳ تا ۴ سال ۴۰ mg\u002Fkg\u002Fday؛ ۵ تا ۱۱ سال ۲۵ تا ۳۵ mg\u002Fkg\u002Fday (سه نوبت). تا ۵۰ mg\u002Fkg\u002Fday مصرف شده.","Titrate over about 3 days to maintenance: 3–4 y 40 mg\u002Fkg\u002Fday; 5–11 y 25–35 mg\u002Fkg\u002Fday (three doses). Up to 50 mg\u002Fkg\u002Fday has been used.",[151],{"source":99,"section":121},[153,162],{"id":154,"severity":155,"text":156,"refs":159},"ci","block",{"fa":157,"en":158},"حساسیت به گاباپنتین.","Hypersensitivity to gabapentin.",[160],{"source":99,"section":161},"4",{"id":163,"severity":155,"rule":164,"text":166,"refs":169},"under-3",{"maxAge":165},{"value":93,"unit":90},{"fa":167,"en":168},"زیر ۳ سال ثابت نشده.","Not established below 3 years.",[170],{"source":99,"section":171},"8.4",[],[],[],[],{"status":177,"reviewer":178,"date":178},"unverified",null,[180,185,190],{"regimen":82,"formulation":37,"input":181,"expect":184},{"ageYears":182,"weightKg":183},65,70,{"perDose":40,"tabletsPerDoseRounded":5},{"regimen":109,"formulation":37,"input":186,"expect":189},{"ageYears":187,"weightKg":188},14,50,{"perDose":40,"upperPerDose":57},{"regimen":132,"formulation":71,"input":191,"expect":194},{"ageYears":192,"weightKg":193},6,20,{"perDose":195,"upperPerDose":28},66.67,1792078535667]