[{"data":1,"prerenderedAt":186},["ShallowReactive",2],{"drug-ferric-carboxymaltose":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":22,"regimens":36,"contraindications":76,"warnings":86,"renal":96,"monitoring":97,"interactions":98,"review":99,"examples":102,"atc":114,"iran":116,"links":128,"populations":147,"usApproval":181},"ferric-carboxymaltose",1,{"fa":7,"en":8},"فریک کربوکسی‌مالتوز","Ferric carboxymaltose","blood",{"fa":11,"en":12},"آهن تزریقی","Parenteral iron",[14],{"name":15,"market":16},"Injectafer","US",[18,19,20,21],"injectafer","ferinject","فرینجکت","آهن وریدی",[23],{"id":24,"form":25,"route":26,"label":27,"concentration":28,"markets":31,"refs":32},"vial-50","injection","iv","50 mg iron\u002FmL (100, 500, 750, 1000 mg vials)",{"amount":29,"unit":30,"perVolumeMl":5},50,"mg",[16],[33],{"source":34,"section":35},"fda-injectafer","3",[37,62],{"id":38,"disease":39,"label":40,"population":43,"type":46,"unit":30,"dose":47,"refs":49,"durationDays":52,"notes":53},"ge50","iron-deficiency-anemia",{"fa":41,"en":42},"کم‌خونی فقر آهن — ۵۰ kg و بیشتر: ۷۵۰ mg وریدی، دو دوز با فاصله ۷ روز","Iron deficiency anaemia — ≥50 kg: 750 mg IV, two doses ≥7 days apart",{"minAge":44,"minWeightKg":29},{"value":5,"unit":45},"year","fixed",{"perDose":48,"dosesPerDay":5},750,[50],{"source":34,"section":51},"2.2",{"min":5,"max":5},[54],{"text":55,"refs":58},{"fa":56,"en":57},"مجموع ۱۵۰۰ mg در هر دوره. بزرگسال: جایگزین یک دوز ۱۵ mg\u002Fkg تا ۱۰۰۰ mg. برای بیمار با عدم تحمل یا پاسخ ناکافی به آهن خوراکی.","Total 1,500 mg per course. Adults: alternatively a single 15 mg\u002Fkg dose up to 1,000 mg. For intolerance or poor response to oral iron.",[59,60],{"source":34,"section":51},{"source":34,"section":61},"1",{"id":63,"disease":39,"label":64,"population":67,"type":70,"unit":30,"dose":71,"refs":73,"durationDays":75},"lt50",{"fa":65,"en":66},"کم‌خونی فقر آهن — زیر ۵۰ kg (۱ سال به بالا): ۱۵ mg\u002Fkg وریدی، دو دوز با فاصله ۷ روز","Iron deficiency anaemia — \u003C50 kg (≥1 y): 15 mg\u002Fkg IV, two doses ≥7 days apart",{"minAge":68,"maxWeightKg":69},{"value":5,"unit":45},49.99,"weightBased",{"perKgPerDay":72,"dividedDoses":5},15,[74],{"source":34,"section":51},{"min":5,"max":5},[77],{"id":78,"severity":79,"text":80,"refs":83},"hyper","block",{"fa":81,"en":82},"حساسیت به Injectafer.","Hypersensitivity to Injectafer.",[84],{"source":34,"section":85},"4",[87],{"text":88,"refs":91},{"fa":89,"en":90},"هشدار جعبه‌ای: هیپوفسفاتمی شدید و طولانی (استئومالاسی، شکستگی)؛ فسفات پیش از دوره تکراری چک و هیپوفسفاتمی قبلی اصلاح شود.","Boxed warning: severe prolonged hypophosphataemia (osteomalacia, fractures); check phosphate before a repeat course and correct prior hypophosphataemia.",[92,94],{"source":34,"section":93},"Boxed Warning",{"source":34,"section":95},"2.1",[],[],[],{"status":100,"reviewer":101,"date":101},"unverified",null,[103,108],{"regimen":38,"formulation":24,"input":104,"expect":107},{"ageYears":105,"weightKg":106},35,60,{"perDose":48,"mlPerDose":72},{"regimen":63,"formulation":24,"input":109,"expect":112},{"ageYears":110,"weightKg":111},6,20,{"perDose":113,"mlPerDose":110},300,[115],"B03AC",{"status":117,"forms":118,"refs":123},"registered",[119],{"code":120,"en":121,"fa":122},"16954","FERRIC CARBOXYMALTOSE 500MG\u002F10ML VIAL","ویال فریک کاربوکسیمالتوس ۵۰۰ میلی‌گرم \u002F ۱۰ میلی‌لیتر",[124],{"source":125,"section":126,"url":127},"darooyab-generic","G-5550\u002FFerric-Carboxymaltose","https:\u002F\u002Fwww.darooyab.ir\u002FG-5550\u002FFerric-Carboxymaltose",[129,133,137,141,144],{"kind":130,"url":131,"label":132},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=203565","NDA203565",{"kind":134,"url":135,"label":136},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=517b4a19-45b3-4286-9f6a-ced4e10447de","FDA Injectafer",{"kind":138,"url":139,"label":140},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa614037.html","Ferric Carboxymaltose Injection",{"kind":142,"url":143,"label":115},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=B03AC",{"kind":145,"url":127,"label":146},"darooyab","Ferric-Carboxymaltose",{"pregnancy":148,"lactation":157,"pediatric":165,"geriatric":173},{"level":149,"text":150,"quote":153,"refs":154},"caution",{"fa":151,"en":152},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary Parenteral iron administration may be associated with hypersensitivity reactions [ see Warnings and Precautions ( 5.2 )], which may have serious consequences, such as fetal bradycardia ( see Clinical Considerations ).",[155],{"source":34,"section":156},"8.1",{"level":149,"text":158,"quote":161,"refs":162},{"fa":159,"en":160},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary The available published data on the use of ferric carboxymaltose in lactating women demonstrate that iron is present in breast milk.",[163],{"source":34,"section":164},"8.2",{"level":149,"text":166,"quote":169,"refs":170},{"fa":167,"en":168},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","The safety and effectiveness of Injectafer for IDA in pediatric patients aged 1 year and older who have normal kidney function and have either intolerance to oral iron or have had unsatisfactory response to oral iron have been established.",[171],{"source":34,"section":172},"8.4",{"level":149,"text":174,"quote":177,"refs":178},{"fa":175,"en":176},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Of the 1,775 subjects in clinical studies of Injectafer, 50% were 65 years and over, while 25% were 75 years and over.",[179],{"source":34,"section":180},"8.5",{"kind":182,"refs":183,"id":132},"NDA",[184],{"source":34,"section":185},"SPL approval \u002F marketing category",1792111453929]