[{"data":1,"prerenderedAt":126},["ShallowReactive",2],{"drug-efinaconazole":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":20,"regimens":33,"contraindications":53,"warnings":54,"renal":55,"monitoring":56,"interactions":57,"review":58,"examples":61,"atc":62,"iran":64,"usApproval":71,"links":77,"populations":92},"efinaconazole",1,{"fa":7,"en":8},"افیناکونازول","Efinaconazole","dermatology",{"fa":11,"en":12},"ضدقارچ آزولی موضعی ناخن","Topical azole for nails",[14],{"name":15,"market":16},"Jublia","US",[18,19,7],"jublia","جوبلیا",[21],{"id":22,"form":23,"route":24,"label":25,"concentration":26,"markets":28,"refs":29},"sol","solution","topical","10% topical solution with flow-through brush",{"amount":5,"unit":27,"perUnit":27},"application",[16],[30],{"source":31,"section":32},"fda-jublia","3",[34],{"id":35,"disease":36,"label":37,"population":40,"type":44,"unit":45,"dose":46,"refs":50},"ony","onychomycosis",{"fa":38,"en":39},"اونیکومایکوز ناخن پا — روزانه یک بار روی ناخن مبتلا، ۴۸ هفته","Toenail onychomycosis — apply to affected toenails once daily for 48 weeks",{"minAge":41},{"value":42,"unit":43},6,"year","notCalculated","mg",{"reason":47},{"fa":48,"en":49},"کل ناخن، چین‌ها، بستر ناخن، هیپونیکیوم و زیر صفحه ناخن پوشانده شود. فقط موضعی.","Cover the whole nail, nail folds, nail bed, hyponychium and underside of the nail plate. Topical use only.",[51],{"source":31,"section":52},"2",[],[],[],[],[],{"status":59,"reviewer":60,"date":60},"unverified",null,[],[63],"D01AC19",{"status":65,"refs":66},"not-found",[67],{"source":68,"section":69,"url":70},"darooyab-generic","search","https:\u002F\u002Fwww.darooyab.ir\u002FSearch?q=Efinaconazole",{"kind":72,"refs":73,"id":76},"NDA",[74],{"source":31,"section":75},"SPL approval \u002F marketing category","NDA203567",[78,81,85,89],{"kind":79,"url":80,"label":76},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=203567",{"kind":82,"url":83,"label":84},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=922d4d25-c530-11e1-9b21-0800200c9a66","FDA Jublia",{"kind":86,"url":87,"label":88},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa614050.html","Efinaconazole Topical",{"kind":90,"url":91,"label":63},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=D01AC19",{"pregnancy":93,"lactation":102,"pediatric":110,"geriatric":118},{"level":94,"text":95,"quote":98,"refs":99},"caution",{"fa":96,"en":97},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary There are no available human data for the use of JUBLIA during pregnancy to inform any drug associated risks of major birth defects, miscarriage, or adverse maternal or fetal outcomes.",[100],{"source":31,"section":101},"8.1",{"level":94,"text":103,"quote":106,"refs":107},{"fa":104,"en":105},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Because many drugs are excreted in human milk, caution should be exercised when JUBLIA is administered to nursing women.",[108],{"source":31,"section":109},"8.2",{"level":94,"text":111,"quote":114,"refs":115},{"fa":112,"en":113},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","Safety and effectiveness of JUBLIA in pediatric subjects under 6 years of age have not been established.",[116],{"source":31,"section":117},"8.4",{"level":94,"text":119,"quote":122,"refs":123},{"fa":120,"en":121},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Of the total number of subjects in clinical trials of JUBLIA, 11.3% were 65 and over, while none were 75 and over.",[124],{"source":31,"section":125},"8.5",1792191540593]