[{"data":1,"prerenderedAt":174},["ShallowReactive",2],{"drug-dobutamine":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":19,"regimens":49,"contraindications":76,"warnings":86,"renal":87,"monitoring":88,"interactions":89,"review":90,"examples":93,"atc":103,"iran":105,"usApproval":125,"links":131,"populations":148},"dobutamine",1,{"fa":7,"en":8},"دوبوتامین","Dobutamine","cardiovascular",{"fa":11,"en":12},"اینوتروپ (آگونیست بتا-۱)","Inotrope (beta-1 agonist)",[14],{"name":15,"market":16},"Dobutrex","US",[18,7],"dobutrex",[20,33,41],{"id":21,"form":22,"route":23,"label":24,"concentration":25,"markets":28,"refs":29},"dil-250","injection","iv","Diluted to 250 mcg\u002FmL (label Table 1)",{"amount":26,"unit":27,"perVolumeMl":5},250,"mcg",[16],[30],{"source":31,"section":32},"fda-dobutamine","Dosage and Administration — Table 1",{"id":34,"form":22,"route":23,"label":35,"concentration":36,"markets":38,"refs":39},"dil-500","Diluted to 500 mcg\u002FmL (label Table 1)",{"amount":37,"unit":27,"perVolumeMl":5},500,[16],[40],{"source":31,"section":32},{"id":42,"form":22,"route":23,"label":43,"concentration":44,"markets":46,"refs":47},"dil-1000","Diluted to 1000 mcg\u002FmL (label Table 1)",{"amount":45,"unit":27,"perVolumeMl":5},1000,[16],[48],{"source":31,"section":32},[50],{"id":51,"disease":52,"label":53,"population":56,"type":60,"unit":27,"dose":61,"refs":64,"notes":67},"std","shock",{"fa":54,"en":55},"افزایش برون‌ده قلب — بزرگسال: معمولاً ۲٫۵ تا ۱۵ mcg\u002Fkg\u002Fدقیقه","Increase cardiac output — adult: usually 2.5–15 mcg\u002Fkg\u002Fmin",{"minAge":57},{"value":58,"unit":59},18,"year","infusion",{"perKgPerMin":62,"perKgPerMinMax":63},2.5,15,[65],{"source":31,"section":66},"Dosage and Administration — Recommended Dosage",[68],{"text":69,"refs":72},{"fa":70,"en":71},"به‌ندرت تا ۴۰ mcg\u002Fkg\u002Fدقیقه. ویال ۱۲٫۵ mg\u002FmL باید دست‌کم در ۵۰ mL رقیق شود؛ با بیکربنات یا محلول قلیایی مخلوط نشود.","Rarely up to 40 mcg\u002Fkg\u002Fmin. The 12.5 mg\u002FmL vial must be diluted to at least 50 mL; not with bicarbonate or alkaline solutions.",[73,74],{"source":31,"section":66},{"source":31,"section":75},"Dosage and Administration",[77],{"id":78,"severity":79,"text":80,"refs":83},"ci","block",{"fa":81,"en":82},"تنگی ساب‌آئورتیک هیپرتروفیک ایدیوپاتیک؛ حساسیت.","Idiopathic hypertrophic subaortic stenosis; hypersensitivity.",[84],{"source":31,"section":85},"Contraindications",[],[],[],[],{"status":91,"reviewer":92,"date":92},"unverified",null,[94],{"regimen":51,"formulation":42,"input":95,"expect":98},{"ageYears":96,"weightKg":97},60,70,{"perMin":99,"mlPerHour":100,"upperPerMin":101,"upperMlPerHour":102},175,10.5,1050,63,[104],"C01CA07",{"status":106,"forms":107,"refs":120},"registered",[108,112,116],{"code":109,"en":110,"fa":111},"20686","DOBUTAMINE 250MG\u002F20ML INJ","فرآورده تزریقی دوبوتامین ۲۵۰ میلی‌گرم \u002F ۲۰ میلی‌لیتر",{"code":113,"en":114,"fa":115},"12984","DOBUTAMINE 250MG\u002F5ML  AMP","آمپول دوبوتامین ۲۵۰ میلی‌گرم \u002F ۵ میلی‌لیتر",{"code":117,"en":118,"fa":119},"00466","DOBUTAMINE HCL 250MG INJ","فرآورده تزریقی دوبوتامین هیدروکلراید ۲۵۰ میلی‌گرم",[121],{"source":122,"section":123,"url":124},"darooyab-generic","G-1648\u002FDobutamine","https:\u002F\u002Fwww.darooyab.ir\u002FG-1648\u002FDobutamine",{"kind":126,"refs":127,"id":130},"ANDA",[128],{"source":31,"section":129},"SPL approval \u002F marketing category","ANDA074086",[132,135,139,143,146],{"kind":133,"url":134,"label":130},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=074086",{"kind":136,"url":137,"label":138},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=89becb0c-da60-4f43-0a98-29ff7a9eca58","FDA Dobutamine",{"kind":140,"url":141,"label":142},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa625018.html","Dobutamine Injection",{"kind":144,"url":145,"label":104},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=C01CA07",{"kind":147,"url":124,"label":8},"darooyab",{"pregnancy":149,"lactation":158,"pediatric":166},{"level":150,"text":151,"quote":154,"refs":155},"caution",{"fa":152,"en":153},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.",[156],{"source":31,"section":157},"Precautions\u002FWarnings – Pregnancy",{"level":150,"text":159,"quote":162,"refs":163},{"fa":160,"en":161},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Because many drugs are excreted in human milk, caution should be exercised when dobutamine hydrochloride is administered to a nursing woman.",[164],{"source":31,"section":165},"Precautions\u002FWarnings – Nursing Mothers",{"level":150,"text":167,"quote":170,"refs":171},{"fa":168,"en":169},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","– The safety and effectiveness of Dobutamine Injection, USP for use in pediatric patients have not been studied.",[172],{"source":31,"section":173},"Precautions\u002FWarnings – Pediatric Use",1792115177643]