[{"data":1,"prerenderedAt":184},["ShallowReactive",2],{"drug-dexmethylphenidate":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":21,"regimens":52,"contraindications":83,"warnings":93,"renal":108,"monitoring":109,"interactions":110,"review":111,"examples":114,"atc":120,"iran":122,"links":129,"populations":146,"usApproval":179},"dexmethylphenidate",1,{"fa":7,"en":8},"دکس‌متیل‌فنیدیت","Dexmethylphenidate","nervous-system",{"fa":11,"en":12},"محرک CNS","CNS stimulant",[14],{"name":15,"market":16},"Focalin","US",[18,19,20],"focalin","فوکالین","دکسمتیلفنیدیت",[22,36,44],{"id":23,"form":24,"route":25,"label":26,"concentration":27,"markets":31,"refs":32},"tab-2-5","tablet","oral","2.5 mg tablet",{"amount":28,"unit":29,"perUnit":24,"scored":30},2.5,"mg",false,[16],[33],{"source":34,"section":35},"fda-focalin","3",{"id":37,"form":24,"route":25,"label":38,"concentration":39,"markets":41,"refs":42},"tab-5","5 mg tablet",{"amount":40,"unit":29,"perUnit":24,"scored":30},5,[16],[43],{"source":34,"section":35},{"id":45,"form":24,"route":25,"label":46,"concentration":47,"markets":49,"refs":50},"tab-10","10 mg tablet",{"amount":48,"unit":29,"perUnit":24,"scored":30},10,[16],[51],{"source":34,"section":35},[53],{"id":54,"disease":54,"label":55,"population":58,"type":62,"unit":29,"dose":63,"refs":65,"limits":68,"notes":72},"adhd",{"fa":56,"en":57},"ADHD (۶ سال به بالا) تازه‌شروع — ۲٫۵ mg دو بار در روز با ۴ ساعت فاصله؛ تا ۱۰ mg دو بار","ADHD (≥6 y), new to methylphenidate — 2.5 mg twice daily 4 h apart; up to 10 mg twice daily",{"minAge":59},{"value":60,"unit":61},6,"year","fixed",{"perDose":28,"perDoseMax":48,"dosesPerDay":64},2,[66],{"source":34,"section":67},"2.2",{"maxPerDay":69,"refs":70},20,[71],{"source":34,"section":67},[73],{"text":74,"refs":77},{"fa":75,"en":76},"هفتگی ۲٫۵ تا ۵ mg افزایش. اگر متیل‌فنیدیت مصرف می‌کند: نصف دوز روزانه متیل‌فنیدیت. پیش از شروع بیماری قلبی و تیک بررسی. اگر طی یک ماه بهبود نیافت قطع.","Increase by 2.5–5 mg weekly. If already on methylphenidate: half the daily methylphenidate dose. Screen for cardiac disease and tics first. Stop if no improvement within a month.",[78,79,81],{"source":34,"section":67},{"source":34,"section":80},"2.1",{"source":34,"section":82},"2.4",[84],{"id":85,"severity":86,"text":87,"refs":90},"ci","block",{"fa":88,"en":89},"حساسیت به متیل‌فنیدیت؛ MAOI همزمان یا ظرف ۱۴ روز (بحران فشار خون).","Hypersensitivity to methylphenidate; MAOIs concomitantly or within 14 days (hypertensive crisis).",[91],{"source":34,"section":92},"4",[94,101],{"text":95,"refs":98},{"fa":96,"en":97},"هشدار جعبه‌ای: پتانسیل بالای سوءمصرف، اعتیاد، بیش‌مصرفی و مرگ.","Boxed warning: high potential for abuse, misuse and addiction, overdose and death.",[99],{"source":34,"section":100},"Boxed Warning",{"text":102,"refs":105},{"fa":103,"en":104},"خطر در بیماری قلبی جدی؛ افزایش فشار و ضربان؛ عوارض روانی؛ پریاپیسم؛ رینود؛ مهار رشد در کودک؛ گلوکوم؛ تیک.","Risk in serious cardiac disease; raised BP and HR; psychiatric reactions; priapism; Raynaud; growth suppression in children; glaucoma; tics.",[106],{"source":34,"section":107},"5",[],[],[],{"status":112,"reviewer":113,"date":113},"unverified",null,[115],{"regimen":54,"formulation":23,"input":116,"expect":119},{"ageYears":117,"weightKg":118},8,25,{"perDose":28,"tabletsPerDoseRounded":5,"perDay":40},[121],"N06BA11",{"status":123,"refs":124},"not-found",[125],{"source":126,"section":127,"url":128},"darooyab-generic","G-3375\u002FDexmethylphenidate","https:\u002F\u002Fwww.darooyab.ir\u002FG-3375\u002FDexmethylphenidate",[130,134,138,141,144],{"kind":131,"url":132,"label":133},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=021278","NDA021278",{"kind":135,"url":136,"label":137},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=2016f5c2-95d2-4655-af65-c588c2bf5e6d","FDA Focalin",{"kind":139,"url":140,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa603014.html",{"kind":142,"url":143,"label":121},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=N06BA11",{"kind":145,"url":128,"label":8},"darooyab",{"pregnancy":147,"lactation":156,"pediatric":163,"geriatric":171},{"level":148,"text":149,"quote":152,"refs":153},"caution",{"fa":150,"en":151},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary Dexmethylphenidate is the d-threo enantiomer of racemic methylphenidate.",[154],{"source":34,"section":155},"8.1",{"level":148,"text":157,"quote":152,"refs":160},{"fa":158,"en":159},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.",[161],{"source":34,"section":162},"8.2",{"level":148,"text":164,"quote":167,"refs":168},{"fa":165,"en":166},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","The safety and effectiveness of Focalin have been established in pediatric patients aged 6 to 17 years in two adequate and well-controlled clinical trials [see Clinical Studies ( 14 )] .",[169],{"source":34,"section":170},"8.4",{"level":148,"text":172,"quote":175,"refs":176},{"fa":173,"en":174},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Focalin has not been studied in the geriatric population.",[177],{"source":34,"section":178},"8.5",{"kind":180,"refs":181,"id":133},"NDA",[182],{"source":34,"section":183},"SPL approval \u002F marketing category",1792191537139]