[{"data":1,"prerenderedAt":203},["ShallowReactive",2],{"drug-cyanocobalamin":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":23,"regimens":37,"contraindications":61,"warnings":71,"renal":79,"monitoring":80,"interactions":81,"review":82,"examples":85,"atc":92,"iran":94,"links":150,"populations":172,"usApproval":198},"cyanocobalamin",1,{"fa":7,"en":8},"سیانوکوبالامین (ویتامین B12)","Cyanocobalamin (vitamin B12)","blood",{"fa":11,"en":12},"ویتامین B12","Vitamin B12",[14],{"name":15,"market":16},"Cyanocobalamin","US",[18,19,20,21,22],"vitamin b12","ویتامین ب۱۲","ب 12","B12","سیانوکوبالامین",[24],{"id":25,"form":26,"route":27,"label":28,"concentration":29,"markets":32,"refs":33},"amp-1000","injection","im","1000 mcg\u002FmL injection",{"amount":30,"unit":31,"perVolumeMl":5},1000,"mcg",[16],[34],{"source":35,"section":36},"fda-cyanocobalamin","How Supplied",[38],{"id":39,"disease":40,"label":41,"population":44,"type":45,"unit":31,"dose":46,"refs":48,"durationDays":51,"notes":54},"pa","b12-deficiency",{"fa":42,"en":43},"کم‌خونی پرنیشیوز — ۱۰۰ mcg عضلانی یا زیرجلدی عمقی روزانه ۶ تا ۷ روز","Pernicious anaemia — 100 mcg IM or deep SC daily for 6–7 days",{},"fixed",{"perDose":47,"dosesPerDay":5},100,[49],{"source":35,"section":50},"Dosage and Administration",{"min":52,"max":53},6,7,[55],{"text":56,"refs":59},{"fa":57,"en":58},"اگر پاسخ رتیکولوسیت: همان دوز یک روز در میان ۷ دوز، سپس هر ۳ تا ۴ روز ۲ تا ۳ هفته، سپس ۱۰۰ mcg ماهانه مادام‌العمر. وریدی نه (دفع ادراری). در صورت نیاز اسید فولیک.","If reticulocyte response: same dose on alternate days for 7 doses, then every 3–4 days for 2–3 weeks, then 100 mcg monthly for life. Not IV (lost in urine). Folic acid if needed.",[60],{"source":35,"section":50},[62],{"id":63,"severity":64,"text":65,"refs":68},"ci","block",{"fa":66,"en":67},"حساسیت به کبالت یا ویتامین B12.","Sensitivity to cobalt and\u002For vitamin B12.",[69],{"source":35,"section":70},"Contraindications",[72],{"text":73,"refs":76},{"fa":74,"en":75},"بیماری لبر (آتروفی سریع عصب بینایی)؛ هیپوکالمی و مرگ ناگهانی در درمان شدید کم‌خونی مگالوبلاستیک؛ آنافیلاکسی (تست داخل‌جلدی در مشکوک)؛ بنزیل الکل در نوزاد نارس.","Leber's disease (rapid optic atrophy); hypokalaemia and sudden death with intensive treatment of severe megaloblastic anaemia; anaphylaxis (intradermal test if suspected); benzyl alcohol in premature infants.",[77],{"source":35,"section":78},"Warnings",[],[],[],{"status":83,"reviewer":84,"date":84},"unverified",null,[86],{"regimen":39,"formulation":25,"input":87,"expect":90},{"ageYears":88,"weightKg":89},60,70,{"perDose":47,"mlPerDose":91},0.1,[93],"B03BA01",{"status":95,"forms":96,"refs":145},"registered",[97,101,105,109,113,117,121,125,129,133,137,141],{"code":98,"en":99,"fa":100},"00646","HYDROXOCOBALAMIN 100MG\u002F1ML AMP","آمپول هیدروکسوکوبالامین ۱۰۰ میلی‌گرم \u002F ۱ میلی‌لیتر",{"code":102,"en":103,"fa":104},"10334","HYDROXOCOBALAMINE ACETATE 0.5MG\u002FML 2ML","هیدروکسوکوبالامین استات ۰٫۵ میلی‌گرم \u002F میلی‌لیتر ۲ میلی‌لیتر",{"code":106,"en":107,"fa":108},"08201","VITAMIN B12 1000MCG TAB","قرص ویتامین B ۱۲ ۱۰۰۰ میکروگرم",{"code":110,"en":111,"fa":112},"01294","VITAMIN B12 1000MCG\u002F1ML AMP","آمپول ویتامین B ۱۲ ۱۰۰۰ میکروگرم \u002F ۱ میلی‌لیتر",{"code":114,"en":115,"fa":116},"11462","VITAMIN B12 1000MCG\u002F4ML AMP","آمپول ویتامین B ۱۲ ۱۰۰۰ میکروگرم \u002F ۴ میلی‌لیتر",{"code":118,"en":119,"fa":120},"01746","VITAMIN B12 100MCG\u002F1ML AMP","آمپول ویتامین B ۱۲ ۱۰۰ میکروگرم \u002F ۱ میلی‌لیتر",{"code":122,"en":123,"fa":124},"11691","VITAMIN B12 1MG\u002F2ML ORAL AMP","آمپول ویتامین B ۱۲ ۱ میلی‌گرم \u002F ۲ میلی‌لیتر",{"code":126,"en":127,"fa":128},"02249","VITAMIN B12 50ML SOL","محلول ویتامین B ۱۲ ۵۰ میلی‌لیتر",{"code":130,"en":131,"fa":132},"18580","CYANOCOBOLAMIN 10ML EYE DROP","قطره چشمی سیانوکوبولامین ۱۰ میلی‌لیتر",{"code":134,"en":135,"fa":136},"23306","HYDROXOCOBALAMIN INJECTION, SOLUTION PARENTERAL 1000 ug\u002F1mL","محلول تزریقی هیدروکسوکوبالامین ۱۰۰۰ میکروگرم \u002F ۱ میلی‌لیتر",{"code":138,"en":139,"fa":140},"51899","HYDROXOCOBALAMIN INJECTION PARENTERAL 5 mg\u002F1mL 2 mL","فرآورده تزریقی هیدروکسوکوبالامین ۵ میلی‌گرم \u002F ۱ میلی‌لیتر ۲ میلی‌لیتر",{"code":142,"en":143,"fa":144},"52710","HYDROXOCOBALAMIN INJECTION, SOLUTION PARENTERAL 1500 ug\u002F1mL 1 mL","محلول تزریقی هیدروکسوکوبالامین ۱۵۰۰ میکروگرم \u002F ۱ میلی‌لیتر ۱ میلی‌لیتر",[146],{"source":147,"section":148,"url":149},"darooyab-generic","G-2950\u002FVitamin-B12","https:\u002F\u002Fwww.darooyab.ir\u002FG-2950\u002FVitamin-B12",[151,155,159,163,166,169],{"kind":152,"url":153,"label":154},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=080737","ANDA080737",{"kind":156,"url":157,"label":158},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=cdd4fd12-e214-43a6-b560-d56fc0d87190","FDA Cyanocobalamin inj",{"kind":160,"url":161,"label":162},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa605007.html","Cyanocobalamin Injection",{"kind":160,"url":164,"label":165},"https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa604029.html","Cyanocobalamin Nasal Gel",{"kind":167,"url":168,"label":93},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=B03BA01",{"kind":170,"url":149,"label":171},"darooyab","Vitamin-B12",{"pregnancy":173,"lactation":182,"pediatric":190},{"level":174,"text":175,"quote":178,"refs":179},"caution",{"fa":176,"en":177},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Category C: Adequate and well-controlled studies have not been done in pregnant women.",[180],{"source":35,"section":181},"Precautions\u002FWarnings – Pregnancy",{"level":174,"text":183,"quote":186,"refs":187},{"fa":184,"en":185},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Vitamin B 12 is known to be excreted in human milk.",[188],{"source":35,"section":189},"Precautions\u002FWarnings – Nursing Mothers",{"level":174,"text":191,"quote":194,"refs":195},{"fa":192,"en":193},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","Intake in children should be in the amount (0.5 to 3 mcg daily) recommended by the Food and Nutrition Board, National Academy of Science-National Research Council.",[196],{"source":35,"section":197},"Precautions\u002FWarnings – Pediatric Use",{"kind":199,"refs":200,"id":154},"ANDA",[201],{"source":35,"section":202},"SPL approval \u002F marketing category",1792191535310]