[{"data":1,"prerenderedAt":259},["ShallowReactive",2],{"drug-covid-vaccine":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":23,"regimens":37,"contraindications":64,"warnings":74,"renal":82,"monitoring":83,"interactions":84,"review":85,"examples":88,"atc":94,"iran":96,"usApproval":204,"links":210,"populations":224},"covid-vaccine",1,{"fa":7,"en":8},"واکسن کووید-۱۹ (mRNA)","COVID-19 vaccine (mRNA)","anti-infectives",{"fa":11,"en":12},"واکسن mRNA","mRNA vaccine",[14],{"name":15,"market":16},"Comirnaty","US",[18,19,20,21,22],"comirnaty","pfizer","فایزر","واکسن کرونا","کووید",[24],{"id":25,"form":26,"route":27,"label":28,"concentration":29,"markets":32,"refs":33},"dose-03","injection","im","0.3 mL single dose (5–11 y vial; ≥12 y prefilled syringe)",{"amount":30,"unit":31,"perVolumeMl":30},0.3,"mL",[16],[34],{"source":35,"section":36},"fda-comirnaty","3",[38],{"id":39,"disease":40,"label":41,"population":44,"type":48,"unit":31,"dose":49,"refs":50,"durationDays":55,"notes":56},"std","covid-19",{"fa":42,"en":43},"کووید-۱۹ — ۵ سال به بالا: یک دوز ۰٫۳ mL عضلانی","COVID-19 — ≥5 y: single 0.3 mL IM dose",{"minAge":45},{"value":46,"unit":47},5,"year","fixed",{"perDose":30,"dosesPerDay":5},[51,53],{"source":35,"section":52},"2.3",{"source":35,"section":54},"2.2",{"min":5,"max":5},[57],{"text":58,"refs":61},{"fa":59,"en":60},"اگر قبلاً واکسن کووید زده، دست‌کم ۲ ماه پس از آخرین دوز. ۵ تا ۱۱ سال: ویال درپوش آبی؛ ۱۲ سال به بالا: سرنگ پرشده خاکستری.","If previously vaccinated, at least 2 months after the last COVID-19 dose. 5–11 y: blue-cap vial; ≥12 y: grey-label prefilled syringe.",[62,63],{"source":35,"section":52},{"source":35,"section":36},[65],{"id":66,"severity":67,"text":68,"refs":71},"allergy","block",{"fa":69,"en":70},"واکنش آلرژیک شدید (آنافیلاکسی) به اجزای واکسن یا دوز قبلی واکسن فایزر.","Severe allergic reaction (anaphylaxis) to a vaccine component or a previous dose of a Pfizer-BioNTech COVID-19 vaccine.",[72],{"source":35,"section":73},"4",[75],{"text":76,"refs":79},{"fa":77,"en":78},"میوکاردیت و پریکاردیت (بیشتر مردان جوان، ظرف چند روز پس از تزریق)؛ سنکوپ.","Myocarditis and pericarditis (mainly young males, within days of vaccination); syncope.",[80],{"source":35,"section":81},"5",[],[],[],{"status":86,"reviewer":87,"date":87},"unverified",null,[89],{"regimen":39,"formulation":25,"input":90,"expect":93},{"ageYears":91,"weightKg":92},40,70,{"perDose":30,"mlPerDose":30},[95],"J07BN01",{"status":97,"forms":98,"refs":199},"registered",[99,103,107,111,115,119,123,127,131,135,139,143,147,151,155,159,163,167,171,175,179,183,187,191,195],{"code":100,"en":101,"fa":102},"52773","COVID-19 VACCINE (1) (adenovirus viral vector) INJECTION PARENTERAL  5 {dose}","فرآورده تزریقی واکسن COVID–۱۹ (۱) (آدنوویروس ناقل ویروسی) ۵ { دوز }",{"code":104,"en":105,"fa":106},"52778","COVID-19 VACCINE (1) (adenovirus viral vector) INJECTION PARENTERAL  1 {dose}","فرآورده تزریقی واکسن COVID–۱۹ (۱) (آدنوویروس ناقل ویروسی) ۱ { دوز }",{"code":108,"en":109,"fa":110},"52849","COVID-19 VACCINE (1) (adenovirus viral vector) INJECTION PARENTERAL  2 {dose}","فرآورده تزریقی واکسن COVID–۱۹ (۱) (آدنوویروس ناقل ویروسی) ۲ { دوز }",{"code":112,"en":113,"fa":114},"52774","COVID-19 VACCINE (2) (adenovirus viral vector) INJECTION PARENTERAL  5 {dose}","فرآورده تزریقی واکسن COVID–۱۹ (۲) (آدنوویروس ناقل ویروسی) ۵ { دوز }",{"code":116,"en":117,"fa":118},"52779","COVID-19 VACCINE (2) (adenovirus viral vector) INJECTION PARENTERAL  1 {dose}","فرآورده تزریقی واکسن COVID–۱۹ (۲) (آدنوویروس ناقل ویروسی) ۱ { دوز }",{"code":120,"en":121,"fa":122},"52850","COVID-19 VACCINE (2) (adenovirus viral vector) INJECTION PARENTERAL  2 {dose}","فرآورده تزریقی واکسن COVID–۱۹ (۲) (آدنوویروس ناقل ویروسی) ۲ { دوز }",{"code":124,"en":125,"fa":126},"52796","COVID-19 VACCINE, CONJUGATE INJECTION PARENTERAL  1 {dose}","فرآورده تزریقی واکسن COVID–۱۹ کونژوگه ۱ { دوز }",{"code":128,"en":129,"fa":130},"52804","COVID-19 VACCINE, CONJUGATE INJECTION PARENTERAL  10 {dose}","فرآورده تزریقی واکسن COVID–۱۹ کونژوگه ۱۰ { دوز }",{"code":132,"en":133,"fa":134},"52874","COVID-19 VACCINE, NON CONJUGATE, RECOMBINANT INJECTION INTRAMUSCULAR  10 {dose}","فرآورده تزریقی واکسن COVID–۱۹ نون کونژوگه نوترکیب ۱۰ { دوز }",{"code":136,"en":137,"fa":138},"52873","COVID-19 VACCINE, NON CONJUGATE, RECOMBINANT INJECTION INTRAMUSCULAR  1 {dose}","فرآورده تزریقی واکسن COVID–۱۹ نون کونژوگه نوترکیب ۱ { دوز }",{"code":140,"en":141,"fa":142},"52935","COVID-19 VACCINE, RECOMBINANT INJECTION, SUSPENSION INTRAMUSCULAR 80 ug\u002F0.5mL 1 {dose}","فرآورده تزریقی واکسن COVID–۱۹ نوترکیب ۸۰ میکروگرم \u002F ۰٫۵ میلی‌لیتر ۱ { دوز }",{"code":144,"en":145,"fa":146},"52929","COVID-19 VACCINE, RECOMBINANT INJECTION, SUSPENSION INTRAMUSCULAR 80 ug\u002F0.5mL 10 {dose}","فرآورده تزریقی واکسن COVID–۱۹ نوترکیب ۸۰ میکروگرم \u002F ۰٫۵ میلی‌لیتر ۱۰ { دوز }",{"code":148,"en":149,"fa":150},"52814","COVID-19 VACCINE, RECOMBINANT (Non-replicating adenovirus vector) INJECTION, SOLUTION INTRAMUSCULAR  10 {dose}","فرآورده تزریقی واکسن COVID–۱۹ نوترکیب (نون–رپلیکاتینگ آدنوویروس وکتور) ۱۰ { دوز }",{"code":152,"en":153,"fa":154},"52895","COVID-19 VACCINE, RECOMBINANT (Protein Subunit) INJECTION, EMULSION INTRAMUSCULAR 25 ug\u002F0.5mL 16 {dose}","فرآورده تزریقی واکسن COVID–۱۹ نوترکیب (زیرواحد پروتئینی) ۲۵ میکروگرم \u002F ۰٫۵ میلی‌لیتر ۱۶ { دوز }",{"code":156,"en":157,"fa":158},"52857","COVID-19 VACCINE, RECOMBINANT (Protein Subunit) INJECTION, EMULSION INTRAMUSCULAR 10 ug\u002F0.2mL 20 {dose}","فرآورده تزریقی واکسن COVID–۱۹ نوترکیب (زیرواحد پروتئینی) ۱۰ میکروگرم \u002F ۰٫۲ میلی‌لیتر ۲۰ { دوز }",{"code":160,"en":161,"fa":162},"52856","COVID-19 VACCINE, RECOMBINANT (Protein Subunit) EMULSION RESPIRATORY 10 ug\u002F0.2mL 20 {dose}","واکسن COVID–۱۹ نوترکیب (زیرواحد پروتئینی) ۱۰ میکروگرم \u002F ۰٫۲ میلی‌لیتر ۲۰ { دوز }",{"code":164,"en":165,"fa":166},"52915","COVID-19 VACCINE, RECOMBINANT (Protein Subunit) INJECTION, EMULSION INTRAMUSCULAR 10 ug\u002F0.2mL 5 {dose}","فرآورده تزریقی واکسن COVID–۱۹ نوترکیب (زیرواحد پروتئینی) ۱۰ میکروگرم \u002F ۰٫۲ میلی‌لیتر ۵ { دوز }",{"code":168,"en":169,"fa":170},"52926","COVID-19 VACCINE, RECOMBINANT (Protein Subunit) INJECTION, EMULSION INTRAMUSCULAR 25 ug\u002F0.5mL 1 {dose}","فرآورده تزریقی واکسن COVID–۱۹ نوترکیب (زیرواحد پروتئینی) ۲۵ میکروگرم \u002F ۰٫۵ میلی‌لیتر ۱ { دوز }",{"code":172,"en":173,"fa":174},"52927","COVID-19 VACCINE, RECOMBINANT (Protein Subunit) INJECTION, EMULSION INTRAMUSCULAR 25 ug\u002F0.5mL 4 {dose}","فرآورده تزریقی واکسن COVID–۱۹ نوترکیب (زیرواحد پروتئینی) ۲۵ میکروگرم \u002F ۰٫۵ میلی‌لیتر ۴ { دوز }",{"code":176,"en":177,"fa":178},"52800","COVID-19 VACCINE, WHOLE VIRION, INACTIVATED, VERO CELL-DERIVED INJECTION PARENTERAL  1 {dose}","فرآورده تزریقی واکسن COVID–۱۹ ویریون کامل غیرفعال‌شده ورو سلولی–مشتق‌شده ۱ { دوز }",{"code":180,"en":181,"fa":182},"52803","COVID-19 VACCINE, WHOLE VIRION, INACTIVATED, VERO CELL-DERIVED INJECTION PARENTERAL  10 {dose}","فرآورده تزریقی واکسن COVID–۱۹ ویریون کامل غیرفعال‌شده ورو سلولی–مشتق‌شده ۱۰ { دوز }",{"code":184,"en":185,"fa":186},"52823","COVID-19 VACCINE, WHOLE VIRION, INACTIVATED, VERO CELL-DERIVED INJECTION PARENTERAL  2 {dose}","فرآورده تزریقی واکسن COVID–۱۹ ویریون کامل غیرفعال‌شده ورو سلولی–مشتق‌شده ۲ { دوز }",{"code":188,"en":189,"fa":190},"52872","COVID-19 VACCINE, WHOLE VIRION, INACTIVATED, VERO CELL-DERIVED INJECTION PARENTERAL  5 {dose}","فرآورده تزریقی واکسن COVID–۱۹ ویریون کامل غیرفعال‌شده ورو سلولی–مشتق‌شده ۵ { دوز }",{"code":192,"en":193,"fa":194},"52884","COVID-19 VACCINE, WHOLE VIRION, INACTIVATED, VERO CELL-DERIVED INJECTION PARENTERAL  20 {dose}","فرآورده تزریقی واکسن COVID–۱۹ ویریون کامل غیرفعال‌شده ورو سلولی–مشتق‌شده ۲۰ { دوز }",{"code":196,"en":197,"fa":198},"52901","COVID-19 VACCINE, WHOLE VIRION, INACTIVATED, VERO CELL-DERIVED INJECTION PARENTERAL  4 {dose}","فرآورده تزریقی واکسن COVID–۱۹ ویریون کامل غیرفعال‌شده ورو سلولی–مشتق‌شده ۴ { دوز }",[200],{"source":201,"section":202,"url":203},"darooyab-generic","G-5434\u002FCovid-19-Vaccine","https:\u002F\u002Fwww.darooyab.ir\u002FG-5434\u002FCovid-19-Vaccine",{"kind":205,"refs":206,"id":209},"BLA",[207],{"source":35,"section":208},"SPL approval \u002F marketing category","BLA125742",[211,214,218,221],{"kind":212,"url":213,"label":209},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=125742",{"kind":215,"url":216,"label":217},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=48c86164-de07-4041-b9dc-f2b5744714e5","FDA Comirnaty",{"kind":219,"url":220,"label":95},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=J07BN01",{"kind":222,"url":203,"label":223},"darooyab","Covid-19-Vaccine",{"pregnancy":225,"lactation":234,"pediatric":242,"geriatric":250},{"level":226,"text":227,"quote":230,"refs":231},"caution",{"fa":228,"en":229},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary All pregnancies have a risk of birth defect, loss, or other adverse outcomes.",[232],{"source":35,"section":233},"8.1",{"level":226,"text":235,"quote":238,"refs":239},{"fa":236,"en":237},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Data are not available to assess the effects of COMIRNATY on the breastfed infant or on milk production\u002Fexcretion.",[240],{"source":35,"section":241},"8.2",{"level":226,"text":243,"quote":246,"refs":247},{"fa":244,"en":245},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","Safety and effectiveness of COMIRNATY in individuals 5 years through 17 years of age with at least one underlying condition that puts them at high risk for severe outcomes from COVID-19 is based on safety and effectiveness data in this age group and in adults [see Adverse Reactions (6) and Clinical Studies (14) ] .",[248],{"source":35,"section":249},"8.4",{"level":251,"text":252,"quote":255,"refs":256},"ok",{"fa":253,"en":254},"برچسب: در سالمندان تفاوت یا تنظیم دوز خاصی ذکر نشده.","Label: no specific difference or dose adjustment stated for older adults.","No overall differences in safety or effectiveness were observed between these recipients and younger recipients.",[257],{"source":35,"section":258},"8.5",1792156172226]